Existence of reprogrammed lymphoma stem cells in a murine ALCL-like model.
Anaplastic Lymphoma Kinase
/ immunology
Animals
CD4-Positive T-Lymphocytes
/ immunology
CD8-Positive T-Lymphocytes
/ immunology
Cell Line
Disease Models, Animal
Female
Gene Expression
/ immunology
Ki-1 Antigen
/ immunology
Lymphoma, Large-Cell, Anaplastic
/ immunology
Lymphoma, T-Cell
/ immunology
Male
Mice
Mice, Inbred C57BL
NIH 3T3 Cells
Stem Cells
/ immunology
Translocation, Genetic
/ immunology
Journal
Leukemia
ISSN: 1476-5551
Titre abrégé: Leukemia
Pays: England
ID NLM: 8704895
Informations de publication
Date de publication:
12 2020
12 2020
Historique:
received:
20
07
2019
accepted:
25
02
2020
revised:
20
02
2020
pubmed:
24
3
2020
medline:
5
1
2021
entrez:
24
3
2020
Statut:
ppublish
Résumé
While cancer stem cells are well established in certain hematologic and solid malignancies, their existence in T cell lymphoma is unclear and the origin of disease is not fully understood. To examine the existence of lymphoma stem cells, we utilized a mouse model of anaplastic large cell lymphoma. Established NPM-ALK
Identifiants
pubmed: 32203142
doi: 10.1038/s41375-020-0789-x
pii: 10.1038/s41375-020-0789-x
pmc: PMC7685983
doi:
Substances chimiques
Ki-1 Antigen
0
Anaplastic Lymphoma Kinase
EC 2.7.10.1
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
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