Fungal Cell Wall and Methyl-β-Cyclodextrin Synergistically Enhance Paclitaxel Biosynthesis and Secretion in Corylus avellana Cell Suspension Culture.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
25 03 2020
25 03 2020
Historique:
received:
15
08
2019
accepted:
11
03
2020
entrez:
28
3
2020
pubmed:
28
3
2020
medline:
24
11
2020
Statut:
epublish
Résumé
Paclitaxel is the top-selling chemotherapeutic drug used for the treatment of lung, ovarian and breast cancer as well as Kaposi's sarcoma. Cell suspension culture (CSC) of Corylus avellana has been addressed as a promising alternative for producing paclitaxel. In this study, endophytic fungus strain YEF
Identifiants
pubmed: 32214149
doi: 10.1038/s41598-020-62196-4
pii: 10.1038/s41598-020-62196-4
pmc: PMC7096423
doi:
Substances chimiques
Culture Media
0
Suspensions
0
beta-Cyclodextrins
0
methyl-beta-cyclodextrin
0
Paclitaxel
P88XT4IS4D
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
5427Références
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