Phylogenetic analysis of the first four SARS-CoV-2 cases in Chile.


Journal

Journal of medical virology
ISSN: 1096-9071
Titre abrégé: J Med Virol
Pays: United States
ID NLM: 7705876

Informations de publication

Date de publication:
09 2020
Historique:
received: 13 03 2020
revised: 25 03 2020
accepted: 26 03 2020
pubmed: 31 3 2020
medline: 29 12 2020
entrez: 31 3 2020
Statut: ppublish

Résumé

The current pandemic caused by the new coronavirus is a worldwide public health concern. To aboard this emergency, and like never before, scientific groups around the world have been working in a fast and coordinated way to get the maximum of information about this virus when it has been almost 3 months since the first cases were detected in Wuhan province in China. The complete genome sequences of around 450 isolates are available, and studies about similarities and differences among them and with the close related viruses that caused similar epidemics in this century. In this work, we studied the complete genome of the first four cases of the new coronavirus disease in Chile, from patients who traveled to Europe and Southeast Asia. Our findings reveal at least two different viral variants entries to Chilean territory, coming from Europe and Asia. We also sub-classified the isolates into variants according to punctual mutations in the genome. Our work contributes to global information about transmission dynamics and the importance to take control measures to stop the spread of the infection.

Identifiants

pubmed: 32222995
doi: 10.1002/jmv.25797
pmc: PMC7228331
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1562-1566

Subventions

Organisme : Institute of Public Health of Chile
Pays : International

Informations de copyright

© 2020 Wiley Periodicals, Inc.

Références

Lancet. 2020 Feb 22;395(10224):565-574
pubmed: 32007145
J Med Virol. 2020 Apr;92(4):455-459
pubmed: 31994738
J Med Virol. 2020 May;92(5):522-528
pubmed: 32027036
J Med Virol. 2020 Sep;92(9):1562-1566
pubmed: 32222995
Chin Med J (Engl). 2020 May 5;133(9):1015-1024
pubmed: 32004165
N Engl J Med. 2020 Feb 20;382(8):692-694
pubmed: 31978293
BMJ. 2020 Jan 8;368:m56
pubmed: 31915179
Nature. 2020 Mar;579(7798):265-269
pubmed: 32015508
Int J Infect Dis. 2020 Apr;93:192-197
pubmed: 32112966
Natl Sci Rev. 2020 Jun;7(6):1012-1023
pubmed: 34676127

Auteurs

Andrés E Castillo (AE)

Molecular Genetics Sub Department, Institute of Public Health of Chile, Santiago, Chile.

Bárbara Parra (B)

Molecular Genetics Sub Department, Institute of Public Health of Chile, Santiago, Chile.

Paz Tapia (P)

Molecular Genetics Sub Department, Institute of Public Health of Chile, Santiago, Chile.

Alejandra Acevedo (A)

Section of Respiratory and Exanthematic Viruses, Institute of Public Health of Chile, Santiago, Chile.

Jaime Lagos (J)

Molecular Genetics Sub Department, Institute of Public Health of Chile, Santiago, Chile.

Winston Andrade (W)

Section of Respiratory and Exanthematic Viruses, Institute of Public Health of Chile, Santiago, Chile.

Loredana Arata (L)

Molecular Genetics Sub Department, Institute of Public Health of Chile, Santiago, Chile.

Gabriel Leal (G)

Section of Respiratory and Exanthematic Viruses, Institute of Public Health of Chile, Santiago, Chile.

Gisselle Barra (G)

Molecular Genetics Sub Department, Institute of Public Health of Chile, Santiago, Chile.

Carolina Tambley (C)

Section of Respiratory and Exanthematic Viruses, Institute of Public Health of Chile, Santiago, Chile.

Javier Tognarelli (J)

Molecular Genetics Sub Department, Institute of Public Health of Chile, Santiago, Chile.

Patricia Bustos (P)

Section of Respiratory and Exanthematic Viruses, Institute of Public Health of Chile, Santiago, Chile.

Soledad Ulloa (S)

Molecular Genetics Sub Department, Institute of Public Health of Chile, Santiago, Chile.

Rodrigo Fasce (R)

Section of Respiratory and Exanthematic Viruses, Institute of Public Health of Chile, Santiago, Chile.

Jorge Fernández (J)

Molecular Genetics Sub Department, Institute of Public Health of Chile, Santiago, Chile.

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Classifications MeSH