Patients with atrial fibrillation and mid-range ejection fraction differ in anticoagulation pattern, thrombotic and mortality risk independently of CHA
Aged
Aged, 80 and over
Anticoagulants
/ administration & dosage
Atrial Fibrillation
/ diagnosis
Clinical Decision Rules
Female
Heart Disease Risk Factors
Hemorrhage
/ chemically induced
Humans
Male
Middle Aged
Predictive Value of Tests
Retrospective Studies
Risk Assessment
Stroke
/ diagnosis
Stroke Volume
Thrombosis
/ diagnosis
Time Factors
Treatment Outcome
Ventricular Function, Left
Atrial fibrillation
Bleeding
Stroke
Survival
Thrombosis
Journal
Heart and vessels
ISSN: 1615-2573
Titre abrégé: Heart Vessels
Pays: Japan
ID NLM: 8511258
Informations de publication
Date de publication:
Sep 2020
Sep 2020
Historique:
received:
24
01
2020
accepted:
27
03
2020
pubmed:
6
4
2020
medline:
15
12
2020
entrez:
6
4
2020
Statut:
ppublish
Résumé
Atrial fibrillation (AF) patients with mid-range left ventricular ejection fraction (mrEF) of 40-49% have neither preserved (pEF > 50%) nor reduced (rEF < 40%) EF and are increasingly being recognized as a distinct group with specific clinical risks. We aimed to retrospectively investigate clinical characteristics and associated thrombotic, bleeding and mortality risks of mrEF in comparison to pEF and rEF in a cohort of 1000 non-valvular AF patients presenting in our institution during the period 2013-2018. Patients with mrEF presented with older age (P < 0.001) and a higher frequency of arterial hypertension (P = 0.001) in comparison to both pEF and rEF patients. In comparison to pEF, mrEF patients were more likely to have diabetes mellitus (P = 0.004), lower HDL-cholesterol (P < 0.001) and lower estimated glomerular filtration rate (P < 0.001), significantly higher CHA
Identifiants
pubmed: 32248252
doi: 10.1007/s00380-020-01603-2
pii: 10.1007/s00380-020-01603-2
doi:
Substances chimiques
Anticoagulants
0
Types de publication
Comparative Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM