Whole genome and phylogenetic analysis of two SARS-CoV-2 strains isolated in Italy in January and February 2020: additional clues on multiple introductions and further circulation in Europe.
Betacoronavirus
/ genetics
COVID-19
China
Coronavirus
/ classification
Coronavirus Infections
/ diagnosis
Genome, Viral
/ genetics
Germany
Humans
Italy
Molecular Epidemiology
Pandemics
Phylogeny
Pneumonia, Viral
/ diagnosis
Point Mutation
RNA, Viral
/ genetics
SARS-CoV-2
Severe Acute Respiratory Syndrome
/ diagnosis
Travel
Whole Genome Sequencing
/ methods
Europe
SARS-CoV-2
Whole genome sequence
phylogenetic analysis
Journal
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
ISSN: 1560-7917
Titre abrégé: Euro Surveill
Pays: Sweden
ID NLM: 100887452
Informations de publication
Date de publication:
04 2020
04 2020
Historique:
entrez:
9
4
2020
pubmed:
9
4
2020
medline:
15
4
2020
Statut:
ppublish
Résumé
Whole genome sequences of SARS-CoV-2 obtained from two patients, a Chinese tourist visiting Rome and an Italian, were compared with sequences from Europe and elsewhere. In a phylogenetic tree, the Italian patient's sequence clustered with sequences from Germany while the tourist's sequence clustered with other European sequences. Some additional European sequences in the tree segregated outside the two clusters containing the patients' sequences. This suggests multiple SARS-CoV-2 introductions in Europe or virus evolution during circulation.
Identifiants
pubmed: 32265007
doi: 10.2807/1560-7917.ES.2020.25.13.2000305
pmc: PMC7140597
doi:
Substances chimiques
RNA, Viral
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Références
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