Case of using mycophenolate in combination with steroids for concurrent macrophage activation syndrome and lupus flare.
connective tissue disease
haematology (incl blood transfusion)
rheumatology
systemic lupus erythematosus
Journal
BMJ case reports
ISSN: 1757-790X
Titre abrégé: BMJ Case Rep
Pays: England
ID NLM: 101526291
Informations de publication
Date de publication:
07 Apr 2020
07 Apr 2020
Historique:
entrez:
10
4
2020
pubmed:
10
4
2020
medline:
1
1
2021
Statut:
epublish
Résumé
This report highlights the importance of tailored treatment strategies in severe systemic lupus erythematosus (SLE) flares driving the life-threatening condition, macrophage activation syndrome (MAS). We report the case of a 42-year-old woman with active systemic lupus erythematosus (SLE) who was diagnosed with MAS within 3 days of onset of lethargy, rash, joint pain and significant cytopenias. This early diagnosis meant that her condition was managed with less intensive immunosuppression with only modest doses of steroids and mycophenolate mofetil.
Identifiants
pubmed: 32269047
pii: 13/4/e231554
doi: 10.1136/bcr-2019-231554
pmc: PMC7167458
pii:
doi:
Substances chimiques
Enzyme Inhibitors
0
Glucocorticoids
0
Prednisolone
9PHQ9Y1OLM
Mycophenolic Acid
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Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
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