Differences in fetal fractional limb volume changes in normal and gestational diabetic pregnancies: an exploratory observational study.
Adult
Arm
/ diagnostic imaging
Diabetes, Gestational
/ diagnostic imaging
Diaphyses
/ diagnostic imaging
Female
Femur
/ diagnostic imaging
Fetal Development
/ physiology
Fetus
/ diagnostic imaging
Gestational Age
Humans
Humerus
/ diagnostic imaging
Japan
Organ Size
Pregnancy
Thigh
/ diagnostic imaging
Ultrasonography, Prenatal
Fractional arm volume
fractional thigh volume
gestational diabetes
third trimester of gestation
Journal
BJOG : an international journal of obstetrics and gynaecology
ISSN: 1471-0528
Titre abrégé: BJOG
Pays: England
ID NLM: 100935741
Informations de publication
Date de publication:
01 2021
01 2021
Historique:
accepted:
07
04
2020
pubmed:
17
4
2020
medline:
5
3
2021
entrez:
17
4
2020
Statut:
ppublish
Résumé
Fetal fractional limb volume has been proposed as a useful measure for quantifying fetal soft tissue development. The aim of this study was to investigate the growth of fractional arm volume (AVol) and fractional thigh volume (TVol) of fetuses with maternal gestational diabetes (GDM) compared with those of fetuses with normal glucose tolerance (NGT). We hypothesised fetal fractional limb volume would be larger in the GDM group than in the NGT group in late gestation. Exploratory observational study. Saitama Municipal Hospital. A total of 165 (125 NGT and 40 GDM) singleton Japanese pregnant women. AVol and TVol were assessed between 20 and 37 weeks' gestation as cylindrical limb volumes based on 50% of the fetal humeral or femoral diaphysis length. Women were diagnosed as GDM based on the criteria of the Japan Society of Obstetrics and Gynecology. AVol and TVol were compared between women with NGT and those with GDM at each gestational age period (2-week intervals from 20 to 37 weeks' gestation). Overall, 287 ultrasound scans were performed (NGT group, 205 scans; GDM group, 82 scans). There was no significant difference of AVol between the groups before 32 weeks' gestation. AVol was significantly larger in the GDM group than in the NGT group after 32 weeks' gestation (P < 0.05). TVol was not statistically different between the groups across gestation. Detection of variations in fetal AVol may provide greater insight into understanding the origins of altered fetal body proportion in GDM. AVol, but not TVol, is significantly larger in fetuses with GDM than in those with NGT after 32 weeks' gestation.
Identifiants
pubmed: 32298518
doi: 10.1111/1471-0528.16265
doi:
Types de publication
Journal Article
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
329-335Subventions
Organisme : Japan Society for the Promotion of Science
ID : JP19K09761
Commentaires et corrections
Type : CommentIn
Informations de copyright
© 2020 Royal College of Obstetricians and Gynaecologists.
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