KIR Variation in Iranians Combines High Haplotype and Allotype Diversity With an Abundance of Functional Inhibitory Receptors.

Alleles Arabs / genetics Haplotypes Histocompatibility Antigens Class I / genetics Humans Iran Killer Cells, Natural / immunology Polymorphism, Genetic / genetics Receptors, KIR / genetics
HLA class I Iranian populations KIR NK cells immune diversity

Journal

Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960

Informations de publication

Date de publication:
2020
Historique:
received: 04 12 2019
accepted: 11 03 2020
entrez: 18 4 2020
pubmed: 18 4 2020
medline: 27 3 2021
Statut: epublish

Résumé

Natural killer (NK) cells are innate lymphocytes that eliminate infected and transformed cells. They discriminate healthy from diseased tissue through killer cell Ig-like receptor (KIR) recognition of HLA class I ligands. Directly impacting NK cell function,

Identifiants

DOI: 10.3389/fimmu.2020.00556 PMID: 32300348 PMC: PMC7142237
pubmed: 32300348
doi: 10.3389/fimmu.2020.00556
pmc: PMC7142237
doi:

Substances chimiques

Histocompatibility Antigens Class I 0
Receptors, KIR 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

556

Subventions

Organisme : NIAID NIH HHS
ID : R01 AI017892
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI128775
Pays : United States
Organisme : NIAID NIH HHS
ID : U01 AI090905
Pays : United States

Informations de copyright

Copyright © 2020 Alicata, Ashouri, Nemat-Gorgani, Guethlein, Marin, Tao, Moretta, Hollenbach, Trowsdale, Traherne, Ghaderi, Parham and Norman.

Références

Blood. 2009 Dec 10;114(25):5182-90
pubmed: 19828694
J Immunol. 2003 Sep 1;171(5):2192-5
pubmed: 12928362
Saudi J Gastroenterol. 2011 May-Jun;17(3):180-4
pubmed: 21546720
J Immunol. 2005 Apr 1;174(7):3859-63
pubmed: 15778339
J Exp Med. 2016 May 2;213(5):791-807
pubmed: 27045007
Nat Genet. 2007 Sep;39(9):1092-9
pubmed: 17694054
J Immunol. 2019 Sep 15;203(6):1629-1635
pubmed: 31405953
J Immunol. 1998 Jul 15;161(2):571-7
pubmed: 9670929
Proc Natl Acad Sci U S A. 2009 Nov 3;106(44):18692-7
pubmed: 19837691
Tissue Antigens. 2003 Jul;62(1):79-86
pubmed: 12859599
PLoS Genet. 2019 Sep 24;15(9):e1008385
pubmed: 31550250
Nucleic Acids Res. 2015 Jan;43(Database issue):D423-31
pubmed: 25414341
Proc Natl Acad Sci U S A. 2000 Apr 25;97(9):4778-83
pubmed: 10781084
Hum Mol Genet. 2010 Mar 1;19(5):737-51
pubmed: 19959527
Tissue Antigens. 2009 Jul;74(1):22-31
pubmed: 19392787
J Immunol. 2005 Oct 15;175(8):5222-9
pubmed: 16210627
J Immunol. 2019 May 1;202(9):2636-2647
pubmed: 30918042
Front Immunol. 2018 Dec 04;9:2843
pubmed: 30564239
Immunogenetics. 2009 Jul;61(7):483-92
pubmed: 19521696
Science. 2011 Oct 7;334(6052):89-94
pubmed: 21868630
J Exp Med. 2006 Mar 20;203(3):633-45
pubmed: 16533882
Trends Immunol. 2018 Jul;39(7):577-590
pubmed: 29793748
J Exp Med. 1995 Mar 1;181(3):1133-44
pubmed: 7532677
Proc Natl Acad Sci U S A. 2019 Jun 25;116(26):12964-12973
pubmed: 31138701
Hum Immunol. 2011 Nov;72(11):1079-83
pubmed: 21867738
Nat Commun. 2019 Jan 31;10(1):514
pubmed: 30705279
Blood. 2010 Oct 7;116(14):2411-9
pubmed: 20581313
J Immunol. 2008 Mar 1;180(5):2922-32
pubmed: 18292514
Front Immunol. 2019 Apr 05;10:605
pubmed: 31024524
Genes Immun. 2009 Mar;10(2):162-73
pubmed: 19005473
Lancet. 1973 Dec 15;2(7842):1383-4
pubmed: 4128069
Annu Rev Genomics Hum Genet. 2006;7:277-300
pubmed: 16824023
J Immunol. 2003 Dec 15;171(12):6640-9
pubmed: 14662867
PLoS Genet. 2013 Oct;9(10):e1003938
pubmed: 24204327
Immunol Rev. 2015 Sep;267(1):259-82
pubmed: 26284483
Curr Opin Immunol. 2017 Feb;44:43-51
pubmed: 27984782
PLoS One. 2012;7(11):e47491
pubmed: 23139747
Blood. 2014 Oct 23;124(17):2744-7
pubmed: 25115891
Immunogenetics. 2010 Feb;62(2):65-73
pubmed: 19936734
J Immunol. 2011 Jan 1;186(1):62-72
pubmed: 21115737
J Immunol. 2002 Nov 1;169(9):5118-29
pubmed: 12391228
Front Immunol. 2012 Aug 20;3:258
pubmed: 22934097
Nat Methods. 2012 Mar 04;9(4):357-9
pubmed: 22388286
Immunity. 1997 Dec;7(6):753-63
pubmed: 9430221
J Exp Med. 1994 Oct 1;180(4):1235-42
pubmed: 7931060
Am J Hum Genet. 2016 Aug 4;99(2):375-91
pubmed: 27486779
Genome Res. 2004 Jun;14(6):1147-59
pubmed: 15140833
Immunity. 2006 Aug;25(2):331-42
pubmed: 16901727
Am J Hum Genet. 1967 May;19(3 Pt 1):233-57
pubmed: 6026583
Sci Immunol. 2017 Jan 13;2(7):
pubmed: 28783669
J Immunol. 2018 Apr 15;200(8):2640-2655
pubmed: 29549179
Front Immunol. 2014 Mar 07;5:87
pubmed: 24639677
J Immunol. 2008 Mar 15;180(6):3969-79
pubmed: 18322206
PLoS One. 2010 Dec 29;5(12):e15115
pubmed: 21206914
Genome Res. 2009 May;19(5):757-69
pubmed: 19411600
J Immunol. 2015 Oct 1;195(7):3160-70
pubmed: 26311903
Immunogenetics. 2014 Nov;66(11):597-611
pubmed: 25139336
Nat Rev Immunol. 2013 Feb;13(2):133-44
pubmed: 23334245
Science. 2016 Jul 29;353(6298):499-503
pubmed: 27417496
Hum Immunol. 2018 Dec;79(12):825-833
pubmed: 30321631
Iran J Public Health. 2014 Jun;43(6):778-86
pubmed: 26110148
HLA. 2016 Sep;88(3):87-99
pubmed: 27558013
Bioinformatics. 2010 Jul 15;26(14):1699-703
pubmed: 20513662
Br J Ophthalmol. 2003 Sep;87(9):1175-83
pubmed: 12928293
Immunogenetics. 2007 Feb;59(2):145-58
pubmed: 17200871
Immunogenetics. 2012 Oct;64(10):719-37
pubmed: 22752190
Brief Bioinform. 2013 Mar;14(2):178-92
pubmed: 22517427
Curr Top Microbiol Immunol. 2006;298:1-21
pubmed: 16329183
Annu Rev Immunol. 2013;31:227-58
pubmed: 23516982
Am J Hum Genet. 2003 Nov;73(5):1162-9
pubmed: 14574645

Auteurs

Claudia Alicata (C)

Department of Immunology, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.

Elham Ashouri (E)

Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, United States.
Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, United States.
Hematology-Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran.
School of Medicine, Shiraz Institute for Cancer Research, Shiraz University of Medical Sciences, Shiraz, Iran.

Neda Nemat-Gorgani (N)

Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, United States.
Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, United States.
Division of Immunology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom.

Lisbeth A Guethlein (LA)

Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, United States.
Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, United States.

Wesley M Marin (WM)

Department of Neurology, University of California, San Francisco, San Francisco, CA, United States.

Sudan Tao (S)

Blood Center of Zhejiang Province, Hangzhou, China.
Division of Personalized Medicine, Department of Immunology and Microbiology, University of Colorado, Anschutz Medical Campus, Aurora, CO, United States.

Lorenzo Moretta (L)

Department of Immunology, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.

Jill A Hollenbach (JA)

Department of Neurology, University of California, San Francisco, San Francisco, CA, United States.

John Trowsdale (J)

Division of Immunology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom.

James A Traherne (JA)

Division of Immunology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom.

Abbas Ghaderi (A)

School of Medicine, Shiraz Institute for Cancer Research, Shiraz University of Medical Sciences, Shiraz, Iran.

Peter Parham (P)

Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, United States.
Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, United States.

Paul J Norman (PJ)

Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, United States.
Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, United States.
Division of Personalized Medicine, Department of Immunology and Microbiology, University of Colorado, Anschutz Medical Campus, Aurora, CO, United States.

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Classifications MeSH

questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Composants de génome › Gènes › Allèles › KIR Variation in Iranians Combines High...
questionsmedicales.fr › Personnes › Disparités en matière de santé, minorités et populations vulnérables › Arabes › KIR Variation in Iranians Combines High...
questionsmedicales.fr › Phénomènes génétiques › Génotype › Haplotypes › KIR Variation in Iranians Combines High...
questionsmedicales.fr › Facteurs biologiques › Antigènes › Isoantigènes › Antigènes d'histocompatibilité › Antigènes d'histocompatibilité de classe I › KIR Variation in Iranians Combines High...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › KIR Variation in Iranians Combines High...
questionsmedicales.fr › Régions géographiques › Asie › Asie de l'Ouest › Moyen Orient › Iran › KIR Variation in Iranians Combines High...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Cellules tueuses naturelles › KIR Variation in Iranians Combines High...
questionsmedicales.fr › Phénomènes génétiques › Variation génétique › Polymorphisme génétique › KIR Variation in Iranians Combines High...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs immunologiques › Récepteurs de cellules tueuses naturelles › Récepteurs KIR › KIR Variation in Iranians Combines High...