[PRIMARY PROSTATIC RHABDOMYOSARCOMA WITH REPEATING CEREBRAL HEMORRHAGE FROM BRAIN METASTASES IN AN ADULT: A CASE REPORT].
Adult
Antineoplastic Combined Chemotherapy Protocols
/ therapeutic use
Brain Neoplasms
/ secondary
Cerebral Hemorrhage
Cyclophosphamide
Dactinomycin
/ administration & dosage
Fatal Outcome
Humans
Male
Prostatic Neoplasms
/ drug therapy
Recurrence
Rhabdomyosarcoma
/ drug therapy
Vincristine
/ administration & dosage
Rhabdomyosarcoma
VAC
prostate
Journal
Nihon Hinyokika Gakkai zasshi. The japanese journal of urology
ISSN: 1884-7110
Titre abrégé: Nihon Hinyokika Gakkai Zasshi
Pays: Japan
ID NLM: 2984841R
Informations de publication
Date de publication:
2019
2019
Historique:
entrez:
21
4
2020
pubmed:
1
1
2019
medline:
4
8
2020
Statut:
ppublish
Résumé
A 28-year-old man visited a nearby doctor with a chief complaint of hematospermia. Magnetic resonance imaging showed a tumor 12-cm in diameter in his pelvis and he was introduced to our hospital. The tumor had replaced the prostate and infiltrated the rectum. He already had multiple lung, pelvic lymph, and bone metastases. He was diagnosed with embryonal rhabdomyosarcoma based on pathological findings after needle tumor biopsy. His disease was stage IV rhabdomyosarcoma according to the Intergroup Rhabdomyosarcoma Study, and he received a VAC (vincristine, actinomycin D, cyclophosphamide) chemotherapy regimen. Despite a partial response with 44% shrinkage in tumor diameter after seven cycles of chemotherapy, he experienced cerebral hemorrhage from small brain metastases during preparation for the eighth course. During gamma knife planning, the cerebral hemorrhage from small brain metastases repeated four times. The patient died 8 months after the introduction of chemotherapy.
Identifiants
pubmed: 32307379
doi: 10.5980/jpnjurol.110.119
doi:
Substances chimiques
Dactinomycin
1CC1JFE158
Vincristine
5J49Q6B70F
Cyclophosphamide
8N3DW7272P
Types de publication
Case Reports
Journal Article
Langues
jpn
Sous-ensembles de citation
IM