Peripheral arterial disease and type 2 diabetes: Older patients still exhibit a survival benefit from glucose control.
Aged
Aged, 80 and over
Austria
/ epidemiology
Biomarkers
/ blood
Blood Glucose
/ drug effects
Cause of Death
Diabetes Mellitus, Type 2
/ blood
Female
Glycated Hemoglobin
/ metabolism
Humans
Hypoglycemic Agents
/ therapeutic use
Male
Middle Aged
Peripheral Arterial Disease
/ diagnosis
Risk Assessment
Risk Factors
Secondary Prevention
Time Factors
Treatment Outcome
Peripheral arterial disease
atherosclerosis
mortality
type 2 diabetes mellitus
Journal
Diabetes & vascular disease research
ISSN: 1752-8984
Titre abrégé: Diab Vasc Dis Res
Pays: England
ID NLM: 101234011
Informations de publication
Date de publication:
Historique:
entrez:
21
4
2020
pubmed:
21
4
2020
medline:
29
9
2020
Statut:
ppublish
Résumé
To investigate a possible beneficial effect of strict glycaemic control on all-cause mortality in patients with peripheral arterial disease and type 2 diabetes mellitus. A total of 367 mainly older peripheral arterial disease patients [age: 69 (62-78) years, 34% women, Fontaine stage I-II] were categorized according to glycaemic control, that is, (a) no type 2 diabetes mellitus, (b) strict glucose control (HbA1c < 53 mmol/mol) and (c) lenient glucose control (HbA1c ⩾ 53 mmol/mol) at inclusion and by mean HbA1c over the first study year. Mortality was analysed using Kaplan-Meier and Cox-regression analyses after 7 years. The combination of type 2 diabetes mellitus and peripheral arterial disease reduced survival from 78.8% to 68.9% in comparison to patients without type 2 diabetes mellitus ( Older patients with peripheral arterial disease and type 2 diabetes mellitus still benefit from strict glucose control in a cohort of patients with similar distribution of cardiovascular risk factors.
Identifiants
pubmed: 32308023
doi: 10.1177/1479164120914845
pmc: PMC7510380
doi:
Substances chimiques
Biomarkers
0
Blood Glucose
0
Glycated Hemoglobin A
0
Hypoglycemic Agents
0
hemoglobin A1c protein, human
0
Types de publication
Comparative Study
Journal Article
Observational Study
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
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