Surgery for Crohn's disease during pregnancy: A nationwide survey.
Adult
Birth Weight
Clinical Decision-Making
Colonoscopy
/ adverse effects
Crohn Disease
/ diagnosis
Female
France
/ epidemiology
Gestational Age
Humans
Infant, Newborn
Maternal Mortality
Perinatal Mortality
Postoperative Complications
/ epidemiology
Pregnancy
Pregnancy Complications
/ diagnosis
Pregnancy Outcome
Retrospective Studies
Severity of Illness Index
Young Adult
Crohn’s disease
pregnancy
surgery
Journal
United European gastroenterology journal
ISSN: 2050-6414
Titre abrégé: United European Gastroenterol J
Pays: England
ID NLM: 101606807
Informations de publication
Date de publication:
07 2020
07 2020
Historique:
pubmed:
25
4
2020
medline:
29
6
2021
entrez:
25
4
2020
Statut:
ppublish
Résumé
Crohn's disease (CD) frequently affects young women and may require surgery during pregnancy. Data regarding operation for CD in expectant mothers are scare. This was a retrospective nationwide survey from the GETAID Chirurgie. Any woman with CD undergoing surgery during pregnancy was eligible. A total of 15 cases were collected between 1992 and 2015. Most operations were performed due to penetrating or stricturing complications. Mean gestational age at delivery was 34 weeks, with a mean birth weight of 2507 g. Maternal post-operative complications occurred in two-thirds of cases. Maternal mortality rate was 6.7% and neonatal mortality rate 9.1%. This is the largest case series of surgery for CD during pregnancy. This operation may have significant morbidity and mortality for mother, fetus, and newborn. Indication needs to be tailored to maternal status, disease severity, and gestational age. Surgery should be managed by experienced gynecologists, physicians, and surgeons. Active CD may be associated with a greater risk to the fetus than the surgical procedure itself.
Sections du résumé
BACKGROUND AND AIMS
Crohn's disease (CD) frequently affects young women and may require surgery during pregnancy. Data regarding operation for CD in expectant mothers are scare.
MATERIALS AND METHODS
This was a retrospective nationwide survey from the GETAID Chirurgie. Any woman with CD undergoing surgery during pregnancy was eligible.
RESULTS
A total of 15 cases were collected between 1992 and 2015. Most operations were performed due to penetrating or stricturing complications. Mean gestational age at delivery was 34 weeks, with a mean birth weight of 2507 g. Maternal post-operative complications occurred in two-thirds of cases. Maternal mortality rate was 6.7% and neonatal mortality rate 9.1%.
CONCLUSIONS
This is the largest case series of surgery for CD during pregnancy. This operation may have significant morbidity and mortality for mother, fetus, and newborn. Indication needs to be tailored to maternal status, disease severity, and gestational age. Surgery should be managed by experienced gynecologists, physicians, and surgeons. Active CD may be associated with a greater risk to the fetus than the surgical procedure itself.
Identifiants
pubmed: 32326876
doi: 10.1177/2050640620921060
pmc: PMC7437090
doi:
Types de publication
Journal Article
Multicenter Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
736-740Commentaires et corrections
Type : CommentIn
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