Recent advances in domesticating non-model microorganisms.
CRISPR
genetic elements
metabolic engineering
non-model microorganism
synthetic biology
Journal
Biotechnology progress
ISSN: 1520-6033
Titre abrégé: Biotechnol Prog
Pays: United States
ID NLM: 8506292
Informations de publication
Date de publication:
09 2020
09 2020
Historique:
received:
22
02
2020
revised:
14
04
2020
accepted:
18
04
2020
pubmed:
25
4
2020
medline:
29
9
2021
entrez:
25
4
2020
Statut:
ppublish
Résumé
Non-model microorganisms have been increasingly explored as microbial cell factories for production of chemicals, fuels, and materials owing to their unique physiology and metabolic capabilities. However, these microorganisms often lack facile genetic tools for strain development, which hinders their adoption as production hosts. In this review, we describe recent advances in domestication of non-model microorganisms, including bacteria, actinobacteria, cyanobacteria, yeast, and fungi, with a focus on the development of genetic tools. In addition, we highlight some successful applications of non-model microorganisms as microbial cell factories.
Types de publication
Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
e3008Subventions
Organisme : U.S. Department of Energy
ID : SC0018420
Pays : International
Organisme : U.S. Department of Energy
ID : SC0018260
Pays : International
Informations de copyright
© 2020 American Institute of Chemical Engineers.
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