Earliest cases of coronavirus disease 2019 (COVID-19) identified in solid organ transplant recipients in the United States.
Aged
COVID-19
Coronavirus Infections
/ complications
End Stage Liver Disease
/ complications
Female
Heart Failure
/ complications
Heart Transplantation
Hospitalization
Humans
Immunosuppression Therapy
/ adverse effects
Kidney Failure, Chronic
/ complications
Kidney Transplantation
Liver Transplantation
Lung Diseases
/ complications
Lung Transplantation
Male
Middle Aged
Outpatients
Pandemics
Pneumonia, Viral
/ complications
Transplant Recipients
United States
/ epidemiology
Vulnerable Populations
Washington
clinical research/practice
infection and infectious agents - viral
infectious disease
lung disease: infectious
organ transplantation in general
outpatient care
Journal
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
ISSN: 1600-6143
Titre abrégé: Am J Transplant
Pays: United States
ID NLM: 100968638
Informations de publication
Date de publication:
Jul 2020
Jul 2020
Historique:
received:
22
03
2020
revised:
16
04
2020
accepted:
20
04
2020
pubmed:
25
4
2020
medline:
21
7
2020
entrez:
25
4
2020
Statut:
ppublish
Résumé
With the rapidly expanding pandemic of SARS-CoV-2, there is concern that solid organ transplant recipients will be particularly vulnerable to infection and may experience a more severe clinical course. We report four cases of COVID-19 in solid organ transplant recipients including recipients of kidney, liver, lung, and heart transplants. We describe each patient's medical history including transplantation history, their clinical presentation and workup, and their course from diagnosis to either hospital discharge or to improvement in symptoms. These reports demonstrate a range of symptoms, clinical severity, and disease course in solid organ transplant recipients with COVID-19, including two hospitalized patients and two patients managed entirely in the outpatient setting.
Identifiants
pubmed: 32330356
doi: 10.1111/ajt.15944
pmc: PMC7264737
pii: S1600-6135(22)22428-9
doi:
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
1885-1890Subventions
Organisme : NHLBI NIH HHS
ID : K23 HL143050
Pays : United States
Organisme : NIAID NIH HHS
ID : T32 AI118690
Pays : United States
Organisme : NIAID NIH HHS
ID : U19 AI113173
Pays : United States
Informations de copyright
© 2020 The American Society of Transplantation and the American Society of Transplant Surgeons.
Références
Am J Transplant. 2020 Jul;20(7):1907-1910
pubmed: 32277591
JAMA. 2020 Mar 17;323(11):1061-1069
pubmed: 32031570
Clin Infect Dis. 2020 Jul 28;71(15):732-739
pubmed: 32150618
Am J Transplant. 2020 Jul;20(7):1941-1943
pubmed: 32233067
Int J Antimicrob Agents. 2020 Mar;55(3):105924
pubmed: 32081636
Intensive Care Med. 2020 May;46(5):846-848
pubmed: 32125452
Eur Urol. 2020 Jun;77(6):742-747
pubmed: 32249089
Lancet Gastroenterol Hepatol. 2020 Jun;5(6):532-533
pubmed: 32278366
Am J Transplant. 2020 Jul;20(7):1864-1868
pubmed: 32277555
Hepatology. 2020 Oct;72(4):1491-1493
pubmed: 32220017
BMJ. 2020 Feb 19;368:m606
pubmed: 32075786
Am J Transplant. 2020 Jul;20(7):1859-1863
pubmed: 32181990
J Heart Lung Transplant. 2020 May;39(5):496-497
pubmed: 32362394
J Clin Microbiol. 2020 May 26;58(6):
pubmed: 32269100
Eur Urol. 2020 Jun;77(6):769-770
pubmed: 32273181
J Biol Regul Homeost Agents. 2020 Mar 14;34(2):327-331
pubmed: 32171193
J Infect. 2020 May;80(5):e1-e6
pubmed: 32171869
Am J Transplant. 2020 Jul;20(7):1869-1874
pubmed: 32243690
Am J Transplant. 2020 Jul;20(7):1944-1946
pubmed: 32282977
Lancet. 2020 Feb 15;395(10223):507-513
pubmed: 32007143