Variation in mobility and exercise adaptations between Drosophila species.
Adaptation, Physiological
Adrenergic Uptake Inhibitors
/ pharmacology
Adrenergic alpha-Agonists
/ pharmacology
Animals
Drosophila
/ classification
Female
Locomotion
/ drug effects
Male
Neurons
/ drug effects
Octopamine
/ pharmacology
Physical Conditioning, Animal
Species Specificity
Tyramine
/ pharmacology
Drosophila
Exercise
Mobility
Octopamine
Journal
Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology
ISSN: 1432-1351
Titre abrégé: J Comp Physiol A Neuroethol Sens Neural Behav Physiol
Pays: Germany
ID NLM: 101141792
Informations de publication
Date de publication:
07 2020
07 2020
Historique:
received:
07
10
2019
accepted:
15
04
2020
revised:
08
04
2020
pubmed:
27
4
2020
medline:
8
9
2021
entrez:
27
4
2020
Statut:
ppublish
Résumé
Locomotion and mobility have been studied extensively in Drosophila melanogaster but less is known about the locomotor capacity of other Drosophila species, while the response to chronic exercise in other species has yet to be examined. We have shown that adult male D. melanogaster adapt to exercise training with improved running endurance, climbing speed, and flight ability compared to unexercised flies. Here, we examine baseline mobility of D. sechellia, D. simulans, and D. virilis, and their response to chronic exercise training. We found significant interspecific differences in mobility and in the response to exercise. Although there is a significant sex difference in exercise adaptations in D. melanogaster, intraspecific analysis reveals few sex differences in other Drosophila species. As octopamine has been shown to be important for exercise adaptations in D. melanogaster, we also asked if any observed differences could be attributed to baseline octopamine levels. We find that octopamine and tyramine levels have the same rank order as baseline climbing speed and endurance in males, but do not predict the response to chronic exercise in males or females. Future research should focus on determining the mechanisms responsible for the inter- and intraspecific differences in mobility and the response to exercise.
Identifiants
pubmed: 32335730
doi: 10.1007/s00359-020-01421-x
pii: 10.1007/s00359-020-01421-x
pmc: PMC7314734
doi:
Substances chimiques
Adrenergic Uptake Inhibitors
0
Adrenergic alpha-Agonists
0
Octopamine
14O50WS8JD
Tyramine
X8ZC7V0OX3
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
611-621Subventions
Organisme : NIDDK NIH HHS
ID : P30 DK020572
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG059683
Pays : United States
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