Molecular Features of Blastic Plasmacytoid Dendritic Cell Neoplasm: DNA Mutations and Epigenetics.

Animals Biomarkers, Tumor Dendritic Cells / metabolism Epigenesis, Genetic Gene Expression Regulation, Neoplastic Genetic Association Studies Genetic Predisposition to Disease High-Throughput Nucleotide Sequencing Humans Mutation Myeloproliferative Disorders / diagnosis Signal Transduction
Azacitidine BRD4 Blastic plasmacytoid dendritic cell neoplasm (BPDCN) Epigenetics Methylation NGS

Journal

Hematology/oncology clinics of North America
ISSN: 1558-1977
Titre abrégé: Hematol Oncol Clin North Am
Pays: United States
ID NLM: 8709473

Informations de publication

Date de publication:
06 2020
Historique:
entrez: 28 4 2020
pubmed: 28 4 2020
medline: 9 2 2021
Statut: ppublish

Résumé

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic neoplasm with a dismal prognosis and no standard therapy. In the past, its cellular ontogenesis was obscure, and BPDCN had been erroneously named CD56

Identifiants

DOI: 10.1016/j.hoc.2020.01.002 PMID: 32336416
pubmed: 32336416
pii: S0889-8588(20)30013-7
doi: 10.1016/j.hoc.2020.01.002
pii:
doi:

Substances chimiques

Biomarkers, Tumor 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

511-521

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Disclosure The authors have nothing to disclose.

Auteurs

Maria Rosaria Sapienza (MR)

Division of Diagnostic Haematopathology, European Institute of Oncology, IRCCS, Via Ripamonti 435, Milan 20141, Italy. Electronic address: mariarosaria.sapienza@ieo.it.

Stefano Pileri (S)

Division of Diagnostic Haematopathology, European Institute of Oncology, IRCCS, Via Ripamonti 435, Milan 20141, Italy.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Molecular Features of Blastic Plasmacytoid...
questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Marqueurs biologiques tumoraux › Molecular Features of Blastic Plasmacytoid...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Système phagocytaire mononucléé › Cellules dendritiques › Molecular Features of Blastic Plasmacytoid...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Épigenèse génétique › Molecular Features of Blastic Plasmacytoid...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Régulation de l'expression des gènes tumoraux › Molecular Features of Blastic Plasmacytoid...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Études d'associations génétiques › Molecular Features of Blastic Plasmacytoid...
questionsmedicales.fr › Phénomènes génétiques › Génotype › Prédisposition génétique à une maladie › Molecular Features of Blastic Plasmacytoid...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Analyse de séquence › Séquençage nucléotidique à haut débit › Molecular Features of Blastic Plasmacytoid...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Molecular Features of Blastic Plasmacytoid...
questionsmedicales.fr › Phénomènes génétiques › Variation génétique › Mutation › Molecular Features of Blastic Plasmacytoid...
questionsmedicales.fr › Hémopathies et maladies lymphatiques › Hémopathies › Maladies de la moelle osseuse › Syndromes myéloprolifératifs › Molecular Features of Blastic Plasmacytoid...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Transduction du signal › Molecular Features of Blastic Plasmacytoid...