What do you need to know about mass spectrometry? A brief guide for endocrinologists.

Androgens / analysis Chromatography, Liquid / methods Diagnostic Techniques, Endocrine / classification Diagnostic Tests, Routine / methods Education, Medical, Continuing Endocrinologists / education Humans Hydrocortisone / analysis Mass Spectrometry / classification Metanephrine / analysis
Hormones Mass spectrometry Spectrométrie de masse

Journal

Annales d'endocrinologie
ISSN: 2213-3941
Titre abrégé: Ann Endocrinol (Paris)
Pays: France
ID NLM: 0116744

Informations de publication

Date de publication:
Jun 2020
Historique:
received: 07 01 2020
accepted: 06 03 2020
pubmed: 29 4 2020
medline: 9 9 2020
entrez: 29 4 2020
Statut: ppublish

Résumé

In routine hormonology, liquid chromatography mass spectrometry (LCMS) is now an established technique for androgen, urinary cortisol and metanephrine assay. It has the undeniable advantage of great analytical specificity, but with sensitivity that clearly depends on financial investment in a very high-end spectrometer. We describe the general principles of LCMS and the routine applications so far developed in hormonology. The purpose is to familiarise endocrinologists with the techniques under development and their pros and cons.

Identifiants

DOI: 10.1016/j.ando.2020.03.021 PMID: 32340850
pubmed: 32340850
pii: S0003-4266(20)30059-7
doi: 10.1016/j.ando.2020.03.021
pii:
doi:

Substances chimiques

Androgens 0
Metanephrine 5001-33-2
Hydrocortisone WI4X0X7BPJ

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

118-123

Informations de copyright

Copyright © 2020 Elsevier Masson SAS. All rights reserved.

Auteurs

Jean-Benoît Corcuff (JB)

Laboratoire d'hormonologie, hôpital Haut-Lévêque, CHU de Bordeaux, 33604 Pessac, France; Nutrition et neurobiologie intégrée, UMR 1286, université de Bordeaux, 33076 Bordeaux, France; Groupe de biologie spécialisée, societé française de medecine nucléaire, 5, rue Ponscarme 75013, Paris, France. Electronic address: jean-benoit.corcuff@chu-bordeaux.fr.

Dominique Ducint (D)

Plateau technique de mesures physiques, hôpital Pellegrin, CHU de Bordeaux, 33600 Bordeaux, France. Electronic address: dominique.ducint@chu-bordeaux.fr.

Julie Brossaud (J)

Laboratoire d'hormonologie, hôpital Haut-Lévêque, CHU de Bordeaux, 33604 Pessac, France; Nutrition et neurobiologie intégrée, UMR 1286, université de Bordeaux, 33076 Bordeaux, France; Groupe de biologie spécialisée, societé française de medecine nucléaire, 5, rue Ponscarme 75013, Paris, France. Electronic address: julie-brossaud@chu-bordeaux.fr.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Hormones, substituts d'hormones et antagonistes d'hormones › Hormones › Androgènes › What do you need to know about mass...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Chromatographie › Chromatographie en phase liquide › What do you need to know about mass...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic endocrinien › What do you need to know about mass...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Tests diagnostiques courants › What do you need to know about mass...
questionsmedicales.fr › Éducation › Enseignement professionnel › Enseignement médical › Formation médicale continue comme sujet › What do you need to know about mass...
questionsmedicales.fr › Établissements, main d'oeuvre et services de soins de santé › Personnel de santé › Médecins › Endocrinologues › What do you need to know about mass...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › What do you need to know about mass...
questionsmedicales.fr › Hormones corticosurrénaliennes › Hydroxycorticostéroïdes › 17-Hydroxycorticostéroïdes › Hydrocortisone › What do you need to know about mass...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Spectrométrie de masse › What do you need to know about mass...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures cycliques › Hydrocarbures aromatiques › Dérivés du benzène › Phénols › Catéchols › Catécholamines › Épinéphrine › Métanéphrine › What do you need to know about mass...