Aortic root valve-sparing repair and dissections in Marfans syndrome during pregnancy: A case series.
Adult
Aortic Dissection
/ surgery
Aorta
/ surgery
Aortic Aneurysm
/ surgery
Aortic Valve
/ surgery
Blood Vessel Prosthesis Implantation
/ methods
Counseling
Female
Humans
Interdisciplinary Communication
Marfan Syndrome
/ surgery
Organ Sparing Treatments
/ methods
Patient Care Team
Perinatal Care
Pregnancy
Pregnancy Complications, Cardiovascular
Pregnancy Outcome
Retrospective Studies
Journal
Journal of cardiac surgery
ISSN: 1540-8191
Titre abrégé: J Card Surg
Pays: United States
ID NLM: 8908809
Informations de publication
Date de publication:
Jul 2020
Jul 2020
Historique:
pubmed:
6
5
2020
medline:
3
11
2020
entrez:
6
5
2020
Statut:
ppublish
Résumé
Marfan syndrome is a connective tissue disorder caused by mutations in the fibrillar FBN-1 gene. Aortic dissection and rupture are major causes of morbidity and mortality and are of special concern during pregnancy. The authors report four cases of aortic root repair with preservation of the native aortic valve that have has created a discussion between cardiothoracic surgeons, obstetricians, and gynecologists regarding the best care for Marfan syndrome patients. We present these cases here with a review of the literature. Surgery of the aorta and valves in Marfan syndrome is less risky than in previous eras and surgical management guidelines are generally accepted. Yet, we may be unnecessarily referring women to terminate pregnancies or to avoid pregnancy. We believe there may be alternative options for these patients. Marfan syndrome during pregnancy can be navigated with preconception counseling, antepartum care, and close postpartum follow-up involving an appropriate multidisciplinary team.
Types de publication
Case Reports
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1439-1443Subventions
Organisme : Mississippi Center for Clinical and Translational Research (MCCTR)
ID : NIGMS U54 GM-115428
Informations de copyright
© 2020 Wiley Periodicals, Inc.
Références
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