Recent advances in properties, production, and applications of L-ribulose.
Bioconversion method
L-Ribulose
Potential application
Rare sugar
Journal
Applied microbiology and biotechnology
ISSN: 1432-0614
Titre abrégé: Appl Microbiol Biotechnol
Pays: Germany
ID NLM: 8406612
Informations de publication
Date de publication:
Jul 2020
Jul 2020
Historique:
received:
20
02
2020
accepted:
20
04
2020
revised:
15
04
2020
pubmed:
7
5
2020
medline:
27
1
2021
entrez:
7
5
2020
Statut:
ppublish
Résumé
Currently, due to the special functions and potential application values, rare sugars become the hot topic in carbohydrate fields. L-Ribulose, an isomer of L-ribose, is an expensive rare ketopentose. As an important precursor for other rare sugars and L-nucleoside analogue synthesis, L-ribulose attracts more and more attention in recent days. Compared with complicated chemical synthesis, the bioconversion method becomes a good alternative approach to L-ribulose production. Generally, the bioconversion of L-ribulose was linked with ribitol, L-arabinose, L-ribose, L-xylulose, and L-arabitol. Herein, an overview of recent advances in the metabolic pathway, chemical synthesis, bioproduction of L-ribulose, and the potential application of L-ribulose is reviewed in detail in this paper. KEY POINTS: 1. L-Ribulose is a rare sugar and the key precursor for L-ribose production. 2. L-Ribulose is the starting material for L-nucleoside derivative synthesis. 3. Chemical synthesis, bioproduction, and applications of L-ribulose are reviewed.
Identifiants
pubmed: 32372201
doi: 10.1007/s00253-020-10637-5
pii: 10.1007/s00253-020-10637-5
doi:
Substances chimiques
Bacterial Proteins
0
Pentoses
0
Sugar Alcohols
0
Ribitol
488-81-3
ribulose
5556-48-9
Xylulose
5962-29-8
Ribose
681HV46001
Arabinose
B40ROO395Z
arabitol
YFV05Y57M9
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
5663-5672Subventions
Organisme : National Natural Science Foundation of China
ID : 31801583
Organisme : National Natural Science Foundation of China
ID : 31922073
Organisme : Natural Science Foundation of Jiangsu Province
ID : BK20180607
Organisme : Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project
ID : TSBICIP-KJGG-003
Organisme : the National First-Class Discipline Program of Food Science and Technology of China
ID : JUFSTR20180203
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