A Paleogenomic Reconstruction of the Deep Population History of the Andes.

Anthropology / methods Central America DNA, Ancient / analysis DNA, Mitochondrial / genetics Gene Flow / genetics Genetics, Population / methods Haplotypes Humans Sequence Analysis, DNA South America
Andes ancient DNA anthropology archaeology population genetics

Journal

Cell
ISSN: 1097-4172
Titre abrégé: Cell
Pays: United States
ID NLM: 0413066

Informations de publication

Date de publication:
28 05 2020
Historique:
received: 29 08 2019
revised: 11 01 2020
accepted: 13 04 2020
pubmed: 11 5 2020
medline: 17 12 2020
entrez: 11 5 2020
Statut: ppublish

Résumé

There are many unanswered questions about the population history of the Central and South Central Andes, particularly regarding the impact of large-scale societies, such as the Moche, Wari, Tiwanaku, and Inca. We assembled genome-wide data on 89 individuals dating from ∼9,000-500 years ago (BP), with a particular focus on the period of the rise and fall of state societies. Today's genetic structure began to develop by 5,800 BP, followed by bi-directional gene flow between the North and South Highlands, and between the Highlands and Coast. We detect minimal admixture among neighboring groups between ∼2,000-500 BP, although we do detect cosmopolitanism (people of diverse ancestries living side-by-side) in the heartlands of the Tiwanaku and Inca polities. We also highlight cases of long-range mobility connecting the Andes to Argentina and the Northwest Andes to the Amazon Basin. VIDEO ABSTRACT.

Identifiants

DOI: 10.1016/j.cell.2020.04.015 PMID: 32386546 PMC: PMC7304944
pubmed: 32386546
pii: S0092-8674(20)30477-3
doi: 10.1016/j.cell.2020.04.015
pmc: PMC7304944
mid: NIHMS1585754
pii:
doi:

Substances chimiques

DNA, Ancient 0
DNA, Mitochondrial 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

1131-1145.e21

Subventions

Organisme : NIGMS NIH HHS
ID : R01 GM100233
Pays : United States
Organisme : Howard Hughes Medical Institute
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM007753
Pays : United States
Organisme : Medical Research Council
Pays : United Kingdom
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Arthritis Research UK
ID : FC001595
Pays : United Kingdom
Organisme : Cancer Research UK
Pays : United Kingdom

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Interests The authors declare no competing interests.

Auteurs

Nathan Nakatsuka (N)

Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA; Harvard-MIT Division of Health Sciences and Technology, Boston, MA 02115, USA. Electronic address: nathan_nakatsuka@hms.harvard.edu.

Iosif Lazaridis (I)

Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.

Chiara Barbieri (C)

Max Planck Institute for the Science of Human History, Jena 07745, Germany; Department of Evolutionary Biology and Environmental Studies, University of Zurich, Zurich 8057, Switzerland.

Pontus Skoglund (P)

Francis Crick Institute, London NW1 1AT, UK.

Nadin Rohland (N)

Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.

Swapan Mallick (S)

Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02446, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.

Cosimo Posth (C)

Max Planck Institute for the Science of Human History, Jena 07745, Germany.

Kelly Harkins-Kinkaid (K)

UCSC Paleogenomics, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.

Matthew Ferry (M)

Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02446, USA.

Éadaoin Harney (É)

Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02446, USA.

Megan Michel (M)

Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02446, USA.

Kristin Stewardson (K)

Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02446, USA.

Jannine Novak-Forst (J)

UCSC Paleogenomics, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.

José M Capriles (JM)

Department of Anthropology, The Pennsylvania State University, University Park, PA 16802, USA.

Marta Alfonso Durruty (MA)

Department of Sociology, Anthropology and Social Work, Kansas State University, Manhattan, KS 66506, USA.

Karina Aranda Álvarez (KA)

Sociedad de Arqueología de La Paz, 5294 La Paz, Bolivia.

David Beresford-Jones (D)

McDonald Institute for Archaeological Research, University of Cambridge, Downing St., Cambridge, CB2 3ER, UK.

Richard Burger (R)

Department of Anthropology, Yale University, New Haven, CT 06511, USA.

Lauren Cadwallader (L)

Office of Scholarly Communication, Cambridge University Library, Cambridge CB3 9DR, UK.

Ricardo Fujita (R)

Centro de Genética y Biología Molecular, Facultdad de Medicina, Universidad de San Martín de Porres, Lima 15011, Peru.

Johny Isla (J)

Peruvian Ministry of Culture, DDC Ica, Directos of the Nasca-Palpa Management Plan, Calle Juan Matta 880, Nasca 11401, Peru.

George Lau (G)

Sainsbury Research Unit, University of East Anglia, Norwich Research Park, Norwich NR4 7TJ, UK.

Carlos Lémuz Aguirre (CL)

Carrera de Arqueología, Universidad Mayor de San Andrés, Edificio Facultad de Ciencias Sociales 3er Piso, La Paz 1995, Bolivia.

Steven LeBlanc (S)

Harvard Peabody Museum, Harvard University, Cambridge, MA 02138, USA.

Sergio Calla Maldonado (SC)

Carrera de Arqueología, Universidad Mayor de San Andrés, Edificio Facultad de Ciencias Sociales 3er Piso, La Paz 1995, Bolivia.

Frank Meddens (F)

School of Archaeology, Geography and Environmental Sciences, University of Reading, Reading, Berkshire, RG6 6AH, UK.

Pablo G Messineo (PG)

INCUAPA-CONICET, Facultad de Ciencias Sociales, Universidad Nacional del Centro de la Provincia de Buenos Aires, Olavarría 7400, Argentina.

Brendan J Culleton (BJ)

Institutes for Energy and the Environment, The Pennsylvania State University, University Park, PA 16802, USA.

Thomas K Harper (TK)

Department of Anthropology, The Pennsylvania State University, University Park, PA 16802, USA.

Jeffrey Quilter (J)

Harvard Peabody Museum, Harvard University, Cambridge, MA 02138, USA.

Gustavo Politis (G)

INCUAPA-CONICET, Facultad de Ciencias Sociales, Universidad Nacional del Centro de la Provincia de Buenos Aires, Olavarría 7400, Argentina.

Kurt Rademaker (K)

Department of Anthropology, Michigan State University, East Lansing, MI 48824, USA.

Markus Reindel (M)

Commission for Archaeology of Non-European Cultures, German Archaeological Institute, Berlin 14195, Germany.

Mario Rivera (M)

Universidad de Magallanes, Punta Arenas 6210427, Chile; Field Museum Natural History 1400 S Lake Shore Dr., Chicago, IL 60605, USA.

Lucy Salazar (L)

McDonald Institute for Archaeological Research, University of Cambridge, Downing St., Cambridge, CB2 3ER, UK.

José R Sandoval (JR)

Centro de Genética y Biología Molecular, Facultdad de Medicina, Universidad de San Martín de Porres, Lima 15011, Peru.

Calogero M Santoro (CM)

Instituto de Alta Investigation, Universidad de Tarapaca, Antafogasta 1520, Arica, 1000000, Chile.

Nahuel Scheifler (N)

INCUAPA-CONICET, Facultad de Ciencias Sociales, Universidad Nacional del Centro de la Provincia de Buenos Aires, Olavarría 7400, Argentina.

Vivien Standen (V)

Departamento de Antropología, Universidad de Tarapacá, Antafogasta 1520, Arica, 1000000, Chile.

Maria Ines Barreto (MI)

Museo de Sitio Huaca Pucllana, Calle General Borgoño, Cuadra 8, Miraflores, Lima 18, Peru.

Isabel Flores Espinoza (IF)

Museo de Sitio Huaca Pucllana, Calle General Borgoño, Cuadra 8, Miraflores, Lima 18, Peru.

Elsa Tomasto-Cagigao (E)

Department of Humanities, Pontifical Catholic University of Peru, San Miguel 15088, Peru.

Guido Valverde (G)

Australian Centre for Ancient DNA, School of Biological Sciences and The Environment Institute, Adelaide University, Adelaide, SA 5005, Australia.

Douglas J Kennett (DJ)

Institutes for Energy and the Environment, The Pennsylvania State University, University Park, PA 16802, USA; Department of Anthropology, The Pennsylvania State University, University Park, PA 16802, USA; Department of Anthropology, University of California, Santa Barbara, Santa Barbara, CA 93106, USA.

Alan Cooper (A)

Australian Centre for Ancient DNA, School of Biological Sciences and The Environment Institute, Adelaide University, Adelaide, SA 5005, Australia.

Johannes Krause (J)

Max Planck Institute for the Science of Human History, Jena 07745, Germany.

Wolfgang Haak (W)

Max Planck Institute for the Science of Human History, Jena 07745, Germany.

Bastien Llamas (B)

Australian Centre for Ancient DNA, School of Biological Sciences and The Environment Institute, Adelaide University, Adelaide, SA 5005, Australia.

David Reich (D)

Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02446, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Department of Human Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA. Electronic address: reich@genetics.med.harvard.edu.

Lars Fehren-Schmitz (L)

UCSC Paleogenomics, University of California, Santa Cruz, Santa Cruz, CA 95064, USA; UCSC Genomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95064, USA. Electronic address: lfehrens@ucsc.edu.

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Classifications MeSH

questionsmedicales.fr › Sciences sociales › Anthropologie › A Paleogenomic Reconstruction of the Deep...
questionsmedicales.fr › Régions géographiques › Amériques › Amérique centrale › A Paleogenomic Reconstruction of the Deep...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ADN › ADN ancien › A Paleogenomic Reconstruction of the Deep...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ADN › ADN mitochondrial › A Paleogenomic Reconstruction of the Deep...
questionsmedicales.fr › Phénomènes génétiques › Fréquence d'allèle › Flux des gènes › A Paleogenomic Reconstruction of the Deep...
questionsmedicales.fr › Disciplines des sciences naturelles › Disciplines des sciences biologiques › Biologie › Génétique › Génétique des populations › A Paleogenomic Reconstruction of the Deep...
questionsmedicales.fr › Phénomènes génétiques › Génotype › Haplotypes › A Paleogenomic Reconstruction of the Deep...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › A Paleogenomic Reconstruction of the Deep...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Analyse de séquence › Analyse de séquence d'ADN › A Paleogenomic Reconstruction of the Deep...
questionsmedicales.fr › Régions géographiques › Amériques › Amérique du Sud › A Paleogenomic Reconstruction of the Deep...