Evaluation of length of stay after transfemoral transcatheter aortic valve implantation with SAPIEN 3 prosthesis: A French multicentre prospective observational trial.


Journal

Archives of cardiovascular diseases
ISSN: 1875-2128
Titre abrégé: Arch Cardiovasc Dis
Pays: Netherlands
ID NLM: 101465655

Informations de publication

Date de publication:
Historique:
received: 23 09 2019
revised: 29 10 2019
accepted: 13 11 2019
pubmed: 19 5 2020
medline: 2 9 2020
entrez: 19 5 2020
Statut: ppublish

Résumé

Complications decrease after transfemoral transcatheter aortic valve implantation (TAVI), and early discharge is feasible and safe in selected populations. To evaluate length of stay (LOS) and reasons for prolonged hospitalisation after transfemoral TAVI in unselected patients. Patients with severe aortic stenosis, who had transfemoral TAVI with the SAPIEN 3 prosthesis using exclusively local anaesthesia, were prospectively and consecutively included at five French high-volume centres. LOS was calculated from TAVI procedure to discharge. Reasons for prolonged hospitalisation (i.e.>3 days) were evaluated. Between 2017 and 2018, 293 patients were included, with a mean age of 82.4±6.5 years and a mean logistic EuroSCORE of 13.7±9.0%. The in-hospital mortality rate was 1.4%. The median LOS was 5 (3-7) days, and varied considerably between centres (from 2 to 7 days). Sixty-four (21.8%) patients were discharged within 3 days after transfemoral TAVI. Reported reasons for prolonged hospitalisation were complications in 62.2%, loss of autonomy in 3.1%, discharge refusal in 2.2% and logistical reasons in 0.9%. In 31.6% of cases, the investigators reported no apparent reasons. The results of our study suggest that LOS after transfemoral TAVI, using the SAPIEN 3 prosthesis and a minimalist approach, varies considerably between centres. In almost a third of cases, hospitalisation was prolonged without any apparent reason. Efforts should be made to educate centres to reduce LOS.

Sections du résumé

BACKGROUND BACKGROUND
Complications decrease after transfemoral transcatheter aortic valve implantation (TAVI), and early discharge is feasible and safe in selected populations.
AIMS OBJECTIVE
To evaluate length of stay (LOS) and reasons for prolonged hospitalisation after transfemoral TAVI in unselected patients.
METHODS METHODS
Patients with severe aortic stenosis, who had transfemoral TAVI with the SAPIEN 3 prosthesis using exclusively local anaesthesia, were prospectively and consecutively included at five French high-volume centres. LOS was calculated from TAVI procedure to discharge. Reasons for prolonged hospitalisation (i.e.>3 days) were evaluated.
RESULTS RESULTS
Between 2017 and 2018, 293 patients were included, with a mean age of 82.4±6.5 years and a mean logistic EuroSCORE of 13.7±9.0%. The in-hospital mortality rate was 1.4%. The median LOS was 5 (3-7) days, and varied considerably between centres (from 2 to 7 days). Sixty-four (21.8%) patients were discharged within 3 days after transfemoral TAVI. Reported reasons for prolonged hospitalisation were complications in 62.2%, loss of autonomy in 3.1%, discharge refusal in 2.2% and logistical reasons in 0.9%. In 31.6% of cases, the investigators reported no apparent reasons.
CONCLUSIONS CONCLUSIONS
The results of our study suggest that LOS after transfemoral TAVI, using the SAPIEN 3 prosthesis and a minimalist approach, varies considerably between centres. In almost a third of cases, hospitalisation was prolonged without any apparent reason. Efforts should be made to educate centres to reduce LOS.

Identifiants

pubmed: 32418883
pii: S1875-2136(20)30117-0
doi: 10.1016/j.acvd.2019.11.010
pii:
doi:

Types de publication

Journal Article Multicenter Study Observational Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

391-400

Informations de copyright

Copyright © 2020 Elsevier Masson SAS. All rights reserved.

Auteurs

Eric Durand (E)

Normandie University, UNIROUEN, INSERM U1096, Department of Cardiology, Rouen University Hospital, FHU REMOD-VHF, 76000 Rouen, France. Electronic address: eric.durand@chu-rouen.fr.

Hervé Le Breton (H)

Rennes University, CHU de Rennes, INSERM LTSI U1099, 35000 Rennes, France.

Thierry Lefevre (T)

Department of Cardiology, Institut Hospitalier Jacques-Cartier-Ramsay Générale de Santé, 91300 Massy, France.

Martine Gilard (M)

Department of Cardiology, Brest University Hospital, 29200 Brest, France.

Dominique Himbert (D)

Department of Cardiology, Bichat Hospital, AP-HP, Faculté de Médecine Paris-Diderot University, 75018 Paris, France.

Marina Urena Alcazar (MU)

Department of Cardiology, Bichat Hospital, AP-HP, Faculté de Médecine Paris-Diderot University, 75018 Paris, France.

Nicolas Bettinger (N)

Normandie University, UNIROUEN, INSERM U1096, Department of Cardiology, Rouen University Hospital, FHU REMOD-VHF, 76000 Rouen, France.

Vincent Auffret (V)

Rennes University, CHU de Rennes, INSERM LTSI U1099, 35000 Rennes, France.

Romain Didier (R)

Department of Cardiology, Brest University Hospital, 29200 Brest, France.

Bernard Chevalier (B)

Department of Cardiology, Institut Hospitalier Jacques-Cartier-Ramsay Générale de Santé, 91300 Massy, France.

Delphine M Béziau (DM)

Normandie University, UNIROUEN, INSERM U1096, Department of Cardiology, Rouen University Hospital, FHU REMOD-VHF, 76000 Rouen, France.

Bernard Iung (B)

Department of Cardiology, Bichat Hospital, AP-HP, Faculté de Médecine Paris-Diderot University, 75018 Paris, France.

Hélène Eltchaninoff (H)

Normandie University, UNIROUEN, INSERM U1096, Department of Cardiology, Rouen University Hospital, FHU REMOD-VHF, 76000 Rouen, France.

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