Meningococcaemia causing necrotizing cellulitis associated with acquired complement deficiency after gastric bypass surgery: a case report.
Case report
Meningococcus; necrotizing fasciitis
Serogroup W
Journal
BMC infectious diseases
ISSN: 1471-2334
Titre abrégé: BMC Infect Dis
Pays: England
ID NLM: 100968551
Informations de publication
Date de publication:
20 May 2020
20 May 2020
Historique:
received:
10
12
2019
accepted:
11
05
2020
entrez:
22
5
2020
pubmed:
22
5
2020
medline:
3
7
2020
Statut:
epublish
Résumé
Neisseria meningitidis has rarely been described as an agent of necrotic soft tissue infection. We report a case of a septic shock with necrotizing cellulitis due to Neisseria meningitidis serogroup W, treated by urgent extensive surgical debridement followed by skin grafts. The invasive meningococcal disease occurred together with a complement deficiency, possibly acquired after bypass surgery that took place 1 year before. Necrotic tissue infections should be considered part of the invasive meningococcal diseases spectrum and should prompt clinicians to look for complement deficiencies. Gastric bypass surgery associated malnutrition may be implicated but further verification is needed.
Sections du résumé
BACKGROUND
BACKGROUND
Neisseria meningitidis has rarely been described as an agent of necrotic soft tissue infection.
CASE PRESENTATION
METHODS
We report a case of a septic shock with necrotizing cellulitis due to Neisseria meningitidis serogroup W, treated by urgent extensive surgical debridement followed by skin grafts. The invasive meningococcal disease occurred together with a complement deficiency, possibly acquired after bypass surgery that took place 1 year before.
CONCLUSIONS
CONCLUSIONS
Necrotic tissue infections should be considered part of the invasive meningococcal diseases spectrum and should prompt clinicians to look for complement deficiencies. Gastric bypass surgery associated malnutrition may be implicated but further verification is needed.
Identifiants
pubmed: 32434466
doi: 10.1186/s12879-020-05079-3
pii: 10.1186/s12879-020-05079-3
pmc: PMC7240913
doi:
Substances chimiques
Complement System Proteins
9007-36-7
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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