SIRPα on CD11c
Animals
CD11c Antigen
/ metabolism
Cell Differentiation
Cells, Cultured
Central Nervous System
/ immunology
Dendritic Cells
/ immunology
Disease Models, Animal
Encephalomyelitis, Autoimmune, Experimental
/ immunology
Humans
Inflammation
/ immunology
Lymphocyte Activation
Mice
Mice, Inbred C57BL
Mice, Knockout
Multiple Sclerosis
/ immunology
Receptors, Immunologic
/ genetics
Th17 Cells
/ immunology
Autoimmunity
CD47
Dendritic Cells
EAE
SIRPα
Journal
European journal of immunology
ISSN: 1521-4141
Titre abrégé: Eur J Immunol
Pays: Germany
ID NLM: 1273201
Informations de publication
Date de publication:
10 2020
10 2020
Historique:
received:
17
09
2019
revised:
12
04
2020
pubmed:
22
5
2020
medline:
12
1
2021
entrez:
22
5
2020
Statut:
ppublish
Résumé
Signal regulatory protein α (SIRPα) is expressed predominantly on type 2 conventional dendritic cells (cDC2s) and macrophages. We previously showed that mice systemically lacking SIRPα were resistant to experimental autoimmune encephalomyelitis (EAE). Here, we showed that deletion of SIRPα in CD11c
Identifiants
pubmed: 32438469
doi: 10.1002/eji.201948410
doi:
Substances chimiques
CD11c Antigen
0
Ptpns1 protein, mouse
0
Receptors, Immunologic
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1560-1570Informations de copyright
© 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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