Relationship between T cell receptor clonotype and PD-1 expression of tumor-infiltrating lymphocytes in colorectal cancer.
Aged
Aged, 80 and over
Breast Neoplasms
/ immunology
CD8-Positive T-Lymphocytes
/ immunology
Clone Cells
Colorectal Neoplasms
/ immunology
Female
Genes, T-Cell Receptor beta
Humans
Immunotherapy, Adoptive
/ methods
Lymphocytes, Tumor-Infiltrating
/ immunology
Male
Middle Aged
Programmed Cell Death 1 Receptor
/ genetics
Receptors, Antigen, T-Cell
/ genetics
PD-1
TCR
TIL
colorectal cancer
repertoire
Journal
European journal of immunology
ISSN: 1521-4141
Titre abrégé: Eur J Immunol
Pays: Germany
ID NLM: 1273201
Informations de publication
Date de publication:
10 2020
10 2020
Historique:
received:
09
09
2019
revised:
15
04
2020
accepted:
19
05
2020
pubmed:
23
5
2020
medline:
12
1
2021
entrez:
23
5
2020
Statut:
ppublish
Résumé
Adoptive T cell therapy using tumor-specific T cells or TCR-modified T cells is a promising next-generation immunotherapy. The major source of tumor-reactive T cells is PD-1
Identifiants
pubmed: 32441316
doi: 10.1002/eji.201948399
doi:
Substances chimiques
Programmed Cell Death 1 Receptor
0
Receptors, Antigen, T-Cell
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1580-1590Informations de copyright
© 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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