Novel Insights into the Thioesterolytic Activity of


Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
21 May 2020
Historique:
received: 21 04 2020
revised: 15 05 2020
accepted: 19 05 2020
entrez: 28 5 2020
pubmed: 28 5 2020
medline: 12 2 2021
Statut: epublish

Résumé

The pyridinium oximes are known esterolytic agents, usually classified in the literature as catalysts, which mimic the catalytic mode of hydrolases. Herein, we combined kinetic and computational studies of the pyridinium-4-oxime-mediated acetylthiocholine (AcSCh

Identifiants

pubmed: 32455554
pii: molecules25102385
doi: 10.3390/molecules25102385
pmc: PMC7287890
pii:
doi:

Substances chimiques

Cholinesterase Inhibitors 0
Cholinesterase Reactivators 0
Oximes 0
Pyridinium Compounds 0
Acetylthiocholine 4468-05-7

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Références

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Auteurs

Blaženka Foretić (B)

Department of Chemistry and Biochemistry, School of Medicine, University of Zagreb, Šalata 3, HR-10000 Zagreb, Croatia.

Vladimir Damjanović (V)

Department of Chemistry and Biochemistry, School of Medicine, University of Zagreb, Šalata 3, HR-10000 Zagreb, Croatia.

Robert Vianello (R)

Division of Organic Chemistry and Biochemistry, Ruđer Bošković Institute, Bijenička 54, HR-10000 Zagreb, Croatia.

Igor Picek (I)

Department of Chemistry and Biochemistry, School of Medicine, University of Zagreb, Šalata 3, HR-10000 Zagreb, Croatia.

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Classifications MeSH