The Genomic History of the Bronze Age Southern Levant.

Archaeology / methods DNA, Ancient / analysis DNA, Mitochondrial / genetics Ethnicity / genetics Gene Flow / genetics Genetic Variation / genetics Genetics, Population / methods Genome, Human / genetics Genomics / methods Haplotypes History, Ancient Human Migration / history Humans Mediterranean Region Middle East Sequence Analysis, DNA
Abel Beth Maacah Baq‛ah Tel Megiddo Tel Shadud Yehud ancient DNA archaeology demographic inference genetic ancestry population genetics

Journal

Cell
ISSN: 1097-4172
Titre abrégé: Cell
Pays: United States
ID NLM: 0413066

Informations de publication

Date de publication:
28 05 2020
Historique:
received: 25 09 2019
revised: 10 02 2020
accepted: 15 04 2020
entrez: 30 5 2020
pubmed: 30 5 2020
medline: 17 12 2020
Statut: ppublish

Résumé

We report genome-wide DNA data for 73 individuals from five archaeological sites across the Bronze and Iron Ages Southern Levant. These individuals, who share the "Canaanite" material culture, can be modeled as descending from two sources: (1) earlier local Neolithic populations and (2) populations related to the Chalcolithic Zagros or the Bronze Age Caucasus. The non-local contribution increased over time, as evinced by three outliers who can be modeled as descendants of recent migrants. We show evidence that different "Canaanite" groups genetically resemble each other more than other populations. We find that Levant-related modern populations typically have substantial ancestry coming from populations related to the Chalcolithic Zagros and the Bronze Age Southern Levant. These groups also harbor ancestry from sources we cannot fully model with the available data, highlighting the critical role of post-Bronze-Age migrations into the region over the past 3,000 years.

Identifiants

DOI: 10.1016/j.cell.2020.04.024 PMID: 32470400 PMC: PMC10212583
pubmed: 32470400
pii: S0092-8674(20)30487-6
doi: 10.1016/j.cell.2020.04.024
pmc: PMC10212583
mid: NIHMS1586612
pii:
doi:

Substances chimiques

DNA, Ancient 0
DNA, Mitochondrial 0

Types de publication

Historical Article Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

1146-1157.e11

Subventions

Organisme : NIGMS NIH HHS
ID : R01 GM100233
Pays : United States
Organisme : Howard Hughes Medical Institute
Pays : United States

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Interests The authors declare no competing interests.

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Auteurs

Lily Agranat-Tamir (L)

Department of Genetics, The Alexander Silberman Institute of Life Sciences, Faculty of Science, The Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat Ram, Jerusalem 9190401, Israel; Department of Statistics, The Hebrew University of Jerusalem, Jerusalem 9190501, Israel.

Shamam Waldman (S)

Braun School of Public Health and Community Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.

Mario A S Martin (MAS)

Institute of Archaeology, Tel Aviv University, Tel Aviv 6997801, Israel.

David Gokhman (D)

Department of Genetics, The Alexander Silberman Institute of Life Sciences, Faculty of Science, The Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat Ram, Jerusalem 9190401, Israel.

Nadav Mishol (N)

Department of Genetics, The Alexander Silberman Institute of Life Sciences, Faculty of Science, The Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat Ram, Jerusalem 9190401, Israel.

Tzilla Eshel (T)

The Fredy and Nadine Herrmann Institute of Earth Sciences, the Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat Ram, Jerusalem 9190401, Israel.

Olivia Cheronet (O)

Department of Evolutionary Anthropology, University of Vienna, Vienna, Austria.

Nadin Rohland (N)

Department of Genetics, Harvard Medical School, Boston, MA 02115, USA; Broad Institute, Cambridge, MA 02138, USA.

Swapan Mallick (S)

Department of Genetics, Harvard Medical School, Boston, MA 02115, USA; Broad Institute, Cambridge, MA 02138, USA; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, USA; Department of Human Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA.

Nicole Adamski (N)

Department of Genetics, Harvard Medical School, Boston, MA 02115, USA; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, USA.

Ann Marie Lawson (AM)

Department of Genetics, Harvard Medical School, Boston, MA 02115, USA; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, USA.

Matthew Mah (M)

Department of Genetics, Harvard Medical School, Boston, MA 02115, USA; Broad Institute, Cambridge, MA 02138, USA; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, USA.

Megan Michel (M)

Department of Genetics, Harvard Medical School, Boston, MA 02115, USA; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, USA.

Jonas Oppenheimer (J)

Department of Genetics, Harvard Medical School, Boston, MA 02115, USA; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, USA.

Kristin Stewardson (K)

Department of Genetics, Harvard Medical School, Boston, MA 02115, USA; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, USA.

Francesca Candilio (F)

School of Archaeology and Earth Institute, University College Dublin, Dublin, Ireland; Soprintendenza ABAP per la città metropolitana di Cagliari e le province di Oristano e Sud Sardegna, Cagliari, Italy.

Denise Keating (D)

School of Archaeology and Earth Institute, University College Dublin, Dublin, Ireland.

Beatriz Gamarra (B)

School of Archaeology and Earth Institute, University College Dublin, Dublin, Ireland; Institut Català de Paleoecologia Humana i Evolució Social, Tarragona, Spain; Universitat Rovira i Virgili, Àrea de Prehistòria, Tarragona, Spain.

Shay Tzur (S)

Braun School of Public Health and Community Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.

Mario Novak (M)

Institute for Anthropological Research, Zagreb, Croatia. Electronic address: mario.novak@inantro.hr.

Rachel Kalisher (R)

Joukowsky Institute for Archaeology and the Ancient World, Brown University, Providence, RI 02912, USA.

Shlomit Bechar (S)

The Institute of Archaeology, The Hebrew University of Jerusalem, Jerusalem 9190501, Israel.

Vered Eshed (V)

Israel Antiquities Authority, P.O.B 586, Jerusalem 91004, Israel.

Douglas J Kennett (DJ)

Department of Anthropology, University of California, Santa Barbara, CA 93106, USA.

Marina Faerman (M)

Laboratory of Bioanthropology and Ancient DNA, Institute of Dental Sciences, Faculty of Dental Medicine, The Hebrew University of Jerusalem, Jerusalem 9112001, Israel.

Naama Yahalom-Mack (N)

The Institute of Archaeology, The Hebrew University of Jerusalem, Jerusalem 9190501, Israel.

Janet M Monge (JM)

University of Pennsylvania Museum of Archaeology and Anthropology, Philadelphia, PA 19104, USA.

Yehuda Govrin (Y)

The Nelson Glueck School of Biblical Archaeology, Hebrew Union College, Jerusalem 9410125, Israel.

Yigal Erel (Y)

The Fredy and Nadine Herrmann Institute of Earth Sciences, the Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat Ram, Jerusalem 9190401, Israel.

Benjamin Yakir (B)

Department of Statistics, The Hebrew University of Jerusalem, Jerusalem 9190501, Israel.

Ron Pinhasi (R)

Department of Evolutionary Anthropology, University of Vienna, Vienna, Austria. Electronic address: ron.pinhasi@univie.ac.at.

Shai Carmi (S)

Braun School of Public Health and Community Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel. Electronic address: shai.carmi@mail.huji.ac.il.

Israel Finkelstein (I)

Institute of Archaeology, Tel Aviv University, Tel Aviv 6997801, Israel. Electronic address: fink2@tauex.tau.ac.il.

Liran Carmel (L)

Department of Genetics, The Alexander Silberman Institute of Life Sciences, Faculty of Science, The Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat Ram, Jerusalem 9190401, Israel. Electronic address: liran.carmel@huji.ac.il.

David Reich (D)

Department of Genetics, Harvard Medical School, Boston, MA 02115, USA; Broad Institute, Cambridge, MA 02138, USA; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, USA; Department of Human Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA. Electronic address: reich@genetics.med.harvard.edu.

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Classifications MeSH

questionsmedicales.fr › Sciences sociales › Anthropologie › Anthropologie culturelle › Archéologie › The Genomic History of the Bronze Age Southern Levant.
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ADN › ADN ancien › The Genomic History of the Bronze Age Southern Levant.
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ADN › ADN mitochondrial › The Genomic History of the Bronze Age Southern Levant.
questionsmedicales.fr › Caractéristiques de la population › Ethnies › The Genomic History of the Bronze Age Southern Levant.
questionsmedicales.fr › Phénomènes génétiques › Fréquence d'allèle › Flux des gènes › The Genomic History of the Bronze Age Southern Levant.
questionsmedicales.fr › Phénomènes génétiques › Variation génétique › The Genomic History of the Bronze Age Southern Levant.
questionsmedicales.fr › Disciplines des sciences naturelles › Disciplines des sciences biologiques › Biologie › Génétique › Génétique des populations › The Genomic History of the Bronze Age Southern Levant.
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Génome humain › The Genomic History of the Bronze Age Southern Levant.
questionsmedicales.fr › Disciplines des sciences naturelles › Disciplines des sciences biologiques › Biologie › Génétique › Génomique › The Genomic History of the Bronze Age Southern Levant.
questionsmedicales.fr › Phénomènes génétiques › Génotype › Haplotypes › The Genomic History of the Bronze Age Southern Levant.
questionsmedicales.fr › Sciences humaines › Histoire › Histoire ancienne › The Genomic History of the Bronze Age Southern Levant.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Mesures épidémiologiques › Démographie › Dynamique des populations › Migration humaine › The Genomic History of the Bronze Age Southern Levant.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › The Genomic History of the Bronze Age Southern Levant.
questionsmedicales.fr › Régions géographiques › Europe › Région méditerranéenne › The Genomic History of the Bronze Age Southern Levant.
questionsmedicales.fr › Régions géographiques › Asie › Asie de l'Ouest › Moyen Orient › The Genomic History of the Bronze Age Southern Levant.
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Analyse de séquence › Analyse de séquence d'ADN › The Genomic History of the Bronze Age Southern Levant.