Longitudinal analysis reveals transition barriers between dominant ecological states in the gut microbiome.
Bacteroides
Prevotella
microbiome
multiomic
state transition
Journal
Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876
Informations de publication
Date de publication:
16 06 2020
16 06 2020
Historique:
pubmed:
31
5
2020
medline:
15
9
2020
entrez:
31
5
2020
Statut:
ppublish
Résumé
The Pioneer 100 Wellness Project involved quantitatively profiling 108 participants' molecular physiology over time, including genomes, gut microbiomes, blood metabolomes, blood proteomes, clinical chemistries, and data from wearable devices. Here, we present a longitudinal analysis focused specifically around the Pioneer 100 gut microbiomes. We distinguished a subpopulation of individuals with reduced gut diversity, elevated relative abundance of the genus
Identifiants
pubmed: 32471946
pii: 1922498117
doi: 10.1073/pnas.1922498117
pmc: PMC7306764
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
13839-13845Informations de copyright
Copyright © 2020 the Author(s). Published by PNAS.
Déclaration de conflit d'intérêts
The authors declare no competing interest.
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