Andrew T Magis

Affiliations

Institute for Systems Biology, Seattle, WA, 98109, USA.

Publications (26)

Small Molecule KRAS Agonist for Mutant KRAS Cancer Therapy.

Molecular cancer

Avec: Ke Xu , Dongkyoo Park , Andrew T Magis , Jun Zhang , Wei Zhou , Gabriel L Sica , Suresh S Ramalingam , Walter J Curran , Xingming Deng

Longitudinal analysis reveals transition barriers between dominant ecological states in the gut microbiome.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Roie Levy , Andrew T Magis , John C Earls , Ohad Manor , Tomasz Wilmanski , Jennifer Lovejoy , Sean M Gibbons , Gilbert S Omenn , Leroy Hood , Nathan D Price

Heterogeneity in statin responses explained by variation in the human gut microbiome.

Med (New York, N.Y.)

Avec: Tomasz Wilmanski , Sergey A Kornilov , Christian Diener , Matthew P Conomos , Jennifer C Lovejoy , Paola Sebastiani , Eric S Orwoll , Leroy Hood , Nathan D Price , Noa Rappaport , Andrew T Magis , Sean M Gibbons

Generally-healthy individuals with aberrant bowel movement frequencies show enrichment for microbially-derived blood metabolites associated with reduced kidney function.

bioRxiv : the preprint server for biology

Avec: Johannes P Johnson-Martínez , Christian Diener , Anne E Levine , Tomasz Wilmanski , David L Suskind , Alexandra Ralevski , Jennifer Hadlock , Andrew T Magis , Leroy Hood , Noa Rappaport , Sean M Gibbons

Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19.

Cell

Avec: Yapeng Su , Daniel Chen , Dan Yuan , Christopher Lausted , Jongchan Choi , Chengzhen L Dai , Valentin Voillet , Venkata R Duvvuri , Kelsey Scherler , Pamela Troisch , Priyanka Baloni , Guangrong Qin , Brett Smith , Sergey A Kornilov , Clifford Rostomily , Alex Xu , Jing Li , Shen Dong , Alissa Rothchild , Jing Zhou , Kim Murray , Rick Edmark , Sunga Hong , John E Heath , John Earls , Rongyu Zhang , Jingyi Xie , Sarah Li , Ryan Roper , Lesley Jones , Yong Zhou , Lee Rowen , Rachel Liu , Sean Mackay , D Shane O'Mahony , Christopher R Dale , Julie A Wallick , Heather A Algren , Michael A Zager , Auteur inconnu , Wei Wei , Nathan D Price , Sui Huang , Naeha Subramanian , Kai Wang , Andrew T Magis , Jenn J Hadlock , Leroy Hood , Alan Aderem , Jeffrey A Bluestone , Lewis L Lanier , Philip D Greenberg , Raphael Gottardo , Mark M Davis , Jason D Goldman , James R Heath

Mcl-1 Interacts with Akt to Promote Lung Cancer Progression.

Cancer research

Avec: Guo Chen , Dongkyoo Park , Andrew T Magis , Madhusmita Behera , Suresh S Ramalingam , Taofeek K Owonikoko , Gabriel L Sica , Keqiang Ye , Chao Zhang , Zhengjia Chen , Walter J Curran , Xingming Deng

Multiomic blood correlates of genetic risk identify presymptomatic disease alterations.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Michael Wainberg , Andrew T Magis , John C Earls , Jennifer C Lovejoy , Nasa Sinnott-Armstrong , Gilbert S Omenn , Leroy Hood , Nathan D Price

Correction to: Small Molecule KRAS Agonist for Mutant KRAS Cancer Therapy.

Molecular cancer

Avec: Ke Xu , Dongkyoo Park , Andrew T Magis , Jun Zhang , Wei Zhou , Gabriel L Sica , Suresh S Ramalingam , Walter J Curran , Xingming Deng

Personal Dense Dynamic Data Clouds Connect Systems Biomedicine to Scientific Wellness.

Methods in molecular biology (Clifton, N.J.)

Avec: Gilbert S Omenn , Andrew T Magis , Nathan D Price , Leroy Hood

Manifestations of Alzheimer's disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90.

Scientific reports

Avec: Laura Heath , John C Earls , Andrew T Magis , Sergey A Kornilov , Jennifer C Lovejoy , Cory C Funk , Noa Rappaport , Benjamin A Logsdon , Lara M Mangravite , Brian W Kunkle , Eden R Martin , Adam C Naj , Nilüfer Ertekin-Taner , Todd E Golde , Leroy Hood , Nathan D Price , Auteur inconnu

Multiple early factors anticipate post-acute COVID-19 sequelae.

Cell

Avec: Yapeng Su , Dan Yuan , Daniel G Chen , Rachel H Ng , Kai Wang , Jongchan Choi , Sarah Li , Sunga Hong , Rongyu Zhang , Jingyi Xie , Sergey A Kornilov , Kelsey Scherler , Ana Jimena Pavlovitch-Bedzyk , Shen Dong , Christopher Lausted , Inyoul Lee , Shannon Fallen , Chengzhen L Dai , Priyanka Baloni , Brett Smith , Venkata R Duvvuri , Kristin G Anderson , Jing Li , Fan Yang , Caroline J Duncombe , Denise J McCulloch , Clifford Rostomily , Pamela Troisch , Jing Zhou , Sean Mackay , Quinn DeGottardi , Damon H May , Ruth Taniguchi , Rachel M Gittelman , Mark Klinger , Thomas M Snyder , Ryan Roper , Gladys Wojciechowska , Kim Murray , Rick Edmark , Simon Evans , Lesley Jones , Yong Zhou , Lee Rowen , Rachel Liu , William Chour , Heather A Algren , William R Berrington , Julie A Wallick , Rebecca A Cochran , Mary E Micikas , Auteur inconnu , Terri Wrin , Christos J Petropoulos , Hunter R Cole , Trevan D Fischer , Wei Wei , Dave S B Hoon , Nathan D Price , Naeha Subramanian , Joshua A Hill , Jennifer Hadlock , Andrew T Magis , Antoni Ribas , Lewis L Lanier , Scott D Boyd , Jeffrey A Bluestone , Helen Chu , Leroy Hood , Raphael Gottardo , Philip D Greenberg , Mark M Davis , Jason D Goldman , James R Heath

Baseline Gut Metagenomic Functional Gene Signature Associated with Variable Weight Loss Responses following a Healthy Lifestyle Intervention in Humans.

mSystems

Avec: Christian Diener , Shizhen Qin , Yong Zhou , Sushmita Patwardhan , Li Tang , Jennifer C Lovejoy , Andrew T Magis , Nathan D Price , Leroy Hood , Sean M Gibbons

Aberrant bowel movement frequencies coincide with increased microbe-derived blood metabolites associated with reduced organ function.

Cell reports. Medicine

Multi-Omic Biological Age Estimation and Its Correlation With Wellness and Disease Phenotypes: A Longitudinal Study of 3,558 Individuals.

The journals of gerontology. Series A, Biological sciences and medical sciences

Avec: John C Earls , Noa Rappaport , Laura Heath , Tomasz Wilmanski , Andrew T Magis , Nicholas J Schork , Gilbert S Omenn , Jennifer Lovejoy , Leroy Hood , Nathan D Price

Genetic Predisposition Impacts Clinical Changes in a Lifestyle Coaching Program.

Scientific reports

Avec: Niha Zubair , Matthew P Conomos , Leroy Hood , Gilbert S Omenn , Nathan D Price , Bonnie J Spring , Andrew T Magis , Jennifer C Lovejoy

Integrated analysis of plasma and single immune cells uncovers metabolic changes in individuals with COVID-19.

Nature biotechnology

Avec: Jihoon W Lee , Yapeng Su , Priyanka Baloni , Daniel Chen , Ana Jimena Pavlovitch-Bedzyk , Dan Yuan , Venkata R Duvvuri , Rachel H Ng , Jongchan Choi , Jingyi Xie , Rongyu Zhang , Kim Murray , Sergey Kornilov , Brett Smith , Andrew T Magis , Dave S B Hoon , Jennifer J Hadlock , Jason D Goldman , Nathan D Price , Raphael Gottardo , Mark M Davis , Leroy Hood , Philip D Greenberg , James R Heath

Characteristics and Factors Associated With Coronavirus Disease 2019 Infection, Hospitalization, and Mortality Across Race and Ethnicity.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Avec: Chengzhen L Dai , Sergey A Kornilov , Ryan T Roper , Hannah Cohen-Cline , Kathleen Jade , Brett Smith , James R Heath , George Diaz , Jason D Goldman , Andrew T Magis , Jennifer J Hadlock

Untargeted longitudinal analysis of a wellness cohort identifies markers of metastatic cancer years prior to diagnosis.

Scientific reports

Avec: Andrew T Magis , Noa Rappaport , Matthew P Conomos , Gilbert S Omenn , Jennifer C Lovejoy , Leroy Hood , Nathan D Price

Blood metabolome predicts gut microbiome α-diversity in humans.

Nature biotechnology

Avec: Tomasz Wilmanski , Noa Rappaport , John C Earls , Andrew T Magis , Ohad Manor , Jennifer Lovejoy , Gilbert S Omenn , Leroy Hood , Sean M Gibbons , Nathan D Price

Gut microbiome pattern reflects healthy ageing and predicts survival in humans.

Nature metabolism

Avec: Tomasz Wilmanski , Christian Diener , Noa Rappaport , Sushmita Patwardhan , Jack Wiedrick , Jodi Lapidus , John C Earls , Anat Zimmer , Gustavo Glusman , Max Robinson , James T Yurkovich , Deborah M Kado , Jane A Cauley , Joseph Zmuda , Nancy E Lane , Andrew T Magis , Jennifer C Lovejoy , Leroy Hood , Sean M Gibbons , Eric S Orwoll , Nathan D Price

Health and disease markers correlate with gut microbiome composition across thousands of people.

Nature communications

Avec: Ohad Manor , Chengzhen L Dai , Sergey A Kornilov , Brett Smith , Nathan D Price , Jennifer C Lovejoy , Sean M Gibbons , Andrew T Magis

Characteristics and Factors Associated with COVID-19 Infection, Hospitalization, and Mortality Across Race and Ethnicity.

medRxiv : the preprint server for health sciences

Avec: Chengzhen L Dai , Sergey A Kornilov , Ryan T Roper , Hannah Cohen-Cline , Kathleen Jade , Brett Smith , James R Heath , George Diaz , Jason D Goldman , Andrew T Magis , Jennifer J Hadlock

DUOX2 variants associate with preclinical disturbances in microbiota-immune homeostasis and increased inflammatory bowel disease risk.

The Journal of clinical investigation

Avec: Helmut Grasberger , Andrew T Magis , Elisa Sheng , Matthew P Conomos , Min Zhang , Lea S Garzotto , Guoqing Hou , Shrinivas Bishu , Hiroko Nagao-Kitamoto , Mohamad El-Zaatari , Sho Kitamoto , Nobuhiko Kamada , Ryan W Stidham , Yasutada Akiba , Jonathan Kaunitz , Yael Haberman , Subra Kugathasan , Lee A Denson , Gilbert S Omenn , John Y Kao

The geometry of clinical labs and wellness states from deeply phenotyped humans.

Nature communications

Avec: Anat Zimmer , Yael Korem , Noa Rappaport , Tomasz Wilmanski , Priyanka Baloni , Kathleen Jade , Max Robinson , Andrew T Magis , Jennifer Lovejoy , Sean M Gibbons , Leroy Hood , Nathan D Price

Genome-microbiome interplay provides insight into the determinants of the human blood metabolome.

Nature metabolism

Avec: Christian Diener , Chengzhen L Dai , Tomasz Wilmanski , Priyanka Baloni , Brett Smith , Noa Rappaport , Leroy Hood , Andrew T Magis , Sean M Gibbons

Multiomic signatures of body mass index identify heterogeneous health phenotypes and responses to a lifestyle intervention.

Nature medicine

Avec: Kengo Watanabe , Tomasz Wilmanski , Christian Diener , John C Earls , Anat Zimmer , Briana Lincoln , Jennifer J Hadlock , Jennifer C Lovejoy , Sean M Gibbons , Andrew T Magis , Leroy Hood , Nathan D Price , Noa Rappaport

Réseau de co-auteurs

Leroy Hood 19 collaborations

Nathan D Price 17 collaborations

Sean M Gibbons 11 collaborations

Noa Rappaport 11 collaborations

Tomasz Wilmanski 10 collaborations

Jennifer C Lovejoy 9 collaborations

Gilbert S Omenn 8 collaborations

John C Earls 7 collaborations

Sergey A Kornilov 7 collaborations

Christian Diener 7 collaborations

Brett Smith 7 collaborations

Chengzhen L Dai 6 collaborations

Priyanka Baloni 5 collaborations

Jason D Goldman 5 collaborations

James R Heath 5 collaborations

Jennifer Lovejoy 4 collaborations

Matthew P Conomos 4 collaborations

Jennifer J Hadlock 4 collaborations

Dongkyoo Park 3 collaborations

Gabriel L Sica 3 collaborations

Suresh S Ramalingam 3 collaborations

Walter J Curran 3 collaborations

Xingming Deng 3 collaborations

Ohad Manor 3 collaborations

Jennifer Hadlock 3 collaborations

Yapeng Su 3 collaborations

Dan Yuan 3 collaborations

Jongchan Choi 3 collaborations

Venkata R Duvvuri 3 collaborations

Kim Murray 3 collaborations

Rongyu Zhang 3 collaborations

Jingyi Xie 3 collaborations

Yong Zhou 3 collaborations

None None 3 collaborations

Philip D Greenberg 3 collaborations

Raphael Gottardo 3 collaborations

Mark M Davis 3 collaborations

Kathleen Jade 3 collaborations

Anat Zimmer 3 collaborations

Ke Xu 2 collaborations

Jun Zhang 2 collaborations

Wei Zhou 2 collaborations

Eric S Orwoll 2 collaborations

Johannes P Johnson-Martínez 2 collaborations

Anne E Levine 2 collaborations

David L Suskind 2 collaborations

Alexandra Ralevski 2 collaborations

Daniel Chen 2 collaborations

Christopher Lausted 2 collaborations

Kelsey Scherler 2 collaborations

Pamela Troisch 2 collaborations

Clifford Rostomily 2 collaborations

Jing Li 2 collaborations

Shen Dong 2 collaborations

Jing Zhou 2 collaborations

Rick Edmark 2 collaborations

Sunga Hong 2 collaborations

Sarah Li 2 collaborations

Ryan Roper 2 collaborations

Lesley Jones 2 collaborations

Lee Rowen 2 collaborations

Rachel Liu 2 collaborations

Sean Mackay 2 collaborations

Julie A Wallick 2 collaborations

Heather A Algren 2 collaborations

Wei Wei 2 collaborations

Naeha Subramanian 2 collaborations

Kai Wang 2 collaborations

Jeffrey A Bluestone 2 collaborations

Lewis L Lanier 2 collaborations

Laura Heath 2 collaborations

Rachel H Ng 2 collaborations

Ana Jimena Pavlovitch-Bedzyk 2 collaborations

Dave S B Hoon 2 collaborations

Sushmita Patwardhan 2 collaborations

Ryan T Roper 2 collaborations

Hannah Cohen-Cline 2 collaborations

George Diaz 2 collaborations

Max Robinson 2 collaborations

Roie Levy 1 collaboration

Paola Sebastiani 1 collaboration

Valentin Voillet 1 collaboration

Guangrong Qin 1 collaboration

Alex Xu 1 collaboration

Alissa Rothchild 1 collaboration

John E Heath 1 collaboration

John Earls 1 collaboration

D Shane O'Mahony 1 collaboration

Christopher R Dale 1 collaboration

Michael A Zager 1 collaboration

Sui Huang 1 collaboration

Jenn J Hadlock 1 collaboration

Alan Aderem 1 collaboration

Guo Chen 1 collaboration

Madhusmita Behera 1 collaboration

Taofeek K Owonikoko 1 collaboration

Keqiang Ye 1 collaboration

Chao Zhang 1 collaboration

Zhengjia Chen 1 collaboration

Michael Wainberg 1 collaboration

Nasa Sinnott-Armstrong 1 collaboration

Cory C Funk 1 collaboration

Benjamin A Logsdon 1 collaboration

Lara M Mangravite 1 collaboration

Brian W Kunkle 1 collaboration

Eden R Martin 1 collaboration

Adam C Naj 1 collaboration

Nilüfer Ertekin-Taner 1 collaboration

Todd E Golde 1 collaboration

Daniel G Chen 1 collaboration

Inyoul Lee 1 collaboration

Shannon Fallen 1 collaboration

Kristin G Anderson 1 collaboration

Fan Yang 1 collaboration

Caroline J Duncombe 1 collaboration

Denise J McCulloch 1 collaboration

Quinn DeGottardi 1 collaboration

Damon H May 1 collaboration

Ruth Taniguchi 1 collaboration

Rachel M Gittelman 1 collaboration

Mark Klinger 1 collaboration

Thomas M Snyder 1 collaboration

Gladys Wojciechowska 1 collaboration

Simon Evans 1 collaboration

William Chour 1 collaboration

William R Berrington 1 collaboration

Rebecca A Cochran 1 collaboration

Mary E Micikas 1 collaboration

Terri Wrin 1 collaboration

Christos J Petropoulos 1 collaboration

Hunter R Cole 1 collaboration

Trevan D Fischer 1 collaboration

Joshua A Hill 1 collaboration

Antoni Ribas 1 collaboration

Scott D Boyd 1 collaboration

Helen Chu 1 collaboration

Shizhen Qin 1 collaboration

Li Tang 1 collaboration

Nicholas J Schork 1 collaboration

Niha Zubair 1 collaboration

Bonnie J Spring 1 collaboration

Jihoon W Lee 1 collaboration

Sergey Kornilov 1 collaboration

Jack Wiedrick 1 collaboration

Jodi Lapidus 1 collaboration

Gustavo Glusman 1 collaboration

James T Yurkovich 1 collaboration

Deborah M Kado 1 collaboration

Jane A Cauley 1 collaboration

Joseph Zmuda 1 collaboration

Nancy E Lane 1 collaboration

Helmut Grasberger 1 collaboration

Elisa Sheng 1 collaboration

Min Zhang 1 collaboration

Lea S Garzotto 1 collaboration

Guoqing Hou 1 collaboration

Shrinivas Bishu 1 collaboration

Hiroko Nagao-Kitamoto 1 collaboration

Mohamad El-Zaatari 1 collaboration

Sho Kitamoto 1 collaboration

Nobuhiko Kamada 1 collaboration

Ryan W Stidham 1 collaboration

Yasutada Akiba 1 collaboration

Jonathan Kaunitz 1 collaboration

Yael Haberman 1 collaboration

Subra Kugathasan 1 collaboration

Lee A Denson 1 collaboration

John Y Kao 1 collaboration

Yael Korem 1 collaboration

Kengo Watanabe 1 collaboration

Briana Lincoln 1 collaboration