Helmut Grasberger

Affiliations

Department of Medicine, University of Michigan, Ann Arbor, MI 48109; and.

Publications (12)

Essential Role of NADPH Oxidase-Dependent Production of Reactive Oxygen Species in Maintenance of Sustained B Cell Receptor Signaling and B Cell Proliferation.

Journal of immunology (Baltimore, Md. : 1950)

Avec: Yang-Yang Feng , Miao Tang , Mitsuhiro Suzuki , Chinthika Gunasekara , Yuki Anbe , Yuichi Hiraoka , Jun Liu , Helmut Grasberger , Mamoru Ohkita , Yasuo Matsumura , Ji-Yang Wang , Takeshi Tsubata

Dual NADPH oxidases DUOX1 and DUOX2 synthesize NAADP and are necessary for Ca

Science signaling

Avec: Feng Gu , Aileen Krüger , Hannes G Roggenkamp , Rick Alpers , Dmitri Lodygin , Vincent Jaquet , Franziska Möckl , Lola C Hernandez C , Kai Winterberg , Andreas Bauche , Anette Rosche , Helmut Grasberger , John Y Kao , Daniel Schetelig , René Werner , Katrin Schröder , Michael Carty , Andrew G Bowie , Samuel Huber , Chris Meier , Hans-Willi Mittrücker , Joerg Heeren , Karl-Heinz Krause , Alexander Flügel , Björn-Philipp Diercks , Andreas H Guse

Citrobacter rodentium Induces Tissue-Resident Memory CD4

Infection and immunity

Avec: S Bishu , G Hou , M El Zaatari , S R Bishu , D Popke , M Zhang , H Grasberger , W Zou , R W Stidham , P D R Higgins , J R Spence , N Kamada , J Y Kao

DUOX2 variants associate with preclinical disturbances in microbiota-immune homeostasis and increased inflammatory bowel disease risk.

The Journal of clinical investigation

Avec: Helmut Grasberger , Andrew T Magis , Elisa Sheng , Matthew P Conomos , Min Zhang , Lea S Garzotto , Guoqing Hou , Shrinivas Bishu , Hiroko Nagao-Kitamoto , Mohamad El-Zaatari , Sho Kitamoto , Nobuhiko Kamada , Ryan W Stidham , Yasutada Akiba , Jonathan Kaunitz , Yael Haberman , Subra Kugathasan , Lee A Denson , Gilbert S Omenn , John Y Kao

CD4+ Tissue-resident Memory T Cells Expand and Are a Major Source of Mucosal Tumour Necrosis Factor α in Active Crohn's Disease.

Journal of Crohn's & colitis

Avec: Shrinivas Bishu , Mohammed El Zaatari , Atsushi Hayashi , Guoqing Hou , Nicole Bowers , Jami Kinnucan , Beth Manoogian , Michelle Muza-Moons , Min Zhang , Helmut Grasberger , Charlie Bourque , Weiping Zou , Peter D R Higgins , Jason R Spence , Ryan W Stidham , Nobuhiko Kamada , John Y Kao

Aim2-mediated/IFN-β-independent regulation of gastric metaplastic lesions via CD8+ T cells.

JCI insight

Avec: Mohamad El-Zaatari , Shrinivas Bishu , Min Zhang , Helmut Grasberger , Guoqing Hou , Henry Haley , Brock Humphries , Li-Jyun Syu , Andrzej A Dlugosz , Kathy Luker , Gary D Luker , Kathryn Eaton , Nobuhiko Kamada , Marilia Cascalho , John Y Kao

Dendritic cell-derived TGF-β mediates the induction of mucosal regulatory T-cell response to Helicobacter infection essential for maintenance of immune tolerance in mice.

Helicobacter

Avec: Stephanie Y Owyang , Min Zhang , Mohamad El-Zaatari , Kathryn A Eaton , Shrinivas Bishu , Guoqing Hou , Helmut Grasberger , John Y Kao

Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut.

Immunity

Avec: Jinzhi Duan , Juan D Matute , Lukas W Unger , Thomas Hanley , Alexandra Schnell , Xi Lin , Niklas Krupka , Paul Griebel , Conner Lambden , Brandon Sit , Joep Grootjans , Michal Pyzik , Felix Sommer , Sina Kaiser , Maren Falk-Paulsen , Helmut Grasberger , John Y Kao , Tobias Fuhrer , Hai Li , Donggi Paik , Yunjin Lee , Samuel Refetoff , Jonathan N Glickman , Adrienne W Paton , Lynn Bry , James C Paton , Uwe Sauer , Andrew J Macpherson , Philip Rosenstiel , Vijay K Kuchroo , Matthew K Waldor , Jun R Huh , Arthur Kaser , Richard S Blumberg

Dietary L-serine confers a competitive fitness advantage to Enterobacteriaceae in the inflamed gut.

Nature microbiology

Avec: Sho Kitamoto , Christopher J Alteri , Michael Rodrigues , Hiroko Nagao-Kitamoto , Kohei Sugihara , Stephanie D Himpsl , Malak Bazzi , Mao Miyoshi , Tatsuki Nishioka , Atsushi Hayashi , Tina L Morhardt , Peter Kuffa , Helmut Grasberger , Mohamad El-Zaatari , Shrinivas Bishu , Chiharu Ishii , Akiyoshi Hirayama , Kathryn A Eaton , Belgin Dogan , Kenneth W Simpson , Naohiro Inohara , Harry L T Mobley , John Y Kao , Shinji Fukuda , Nicolas Barnich , Nobuhiko Kamada

Effects of Anti-Helicobacter pylori Therapy on Incidence of Autoimmune Diseases, Including Inflammatory Bowel Diseases.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Avec: Kun-Der Lin , Guei-Fen Chiu , Akbar K Waljee , Stephanie Y Owyang , Mohamad El-Zaatari , Shrinivas Bishu , Helmut Grasberger , Min Zhang , Deng-Chyang Wu , John Y Kao

The Cxcr2

Frontiers in immunology

Avec: Krystal D Kao , Helmut Grasberger , Mohamad El-Zaatari

STR mutations on chromosome 15q cause thyrotropin resistance by activating a primate-specific enhancer of MIR7-2/MIR1179.

Nature genetics

Avec: Helmut Grasberger , Alexandra M Dumitrescu , Xiao-Hui Liao , Elliott G Swanson , Roy E Weiss , Panudda Srichomkwun , Theodora Pappa , Junfeng Chen , Takashi Yoshimura , Phillip Hoffmann , Monica Malheiros França , Rebecca Tagett , Kazumichi Onigata , Sabine Costagliola , Jane Ranchalis , Mitchell R Vollger , Andrew B Stergachis , Jessica X Chong , Michael J Bamshad , Guillaume Smits , Gilbert Vassart , Samuel Refetoff

Réseau de co-auteurs

John Y Kao 8 collaborations

Shrinivas Bishu 6 collaborations

Mohamad El-Zaatari 6 collaborations

Min Zhang 5 collaborations

Guoqing Hou 4 collaborations

Nobuhiko Kamada 4 collaborations

Hiroko Nagao-Kitamoto 2 collaborations

Sho Kitamoto 2 collaborations

Ryan W Stidham 2 collaborations

Atsushi Hayashi 2 collaborations

Stephanie Y Owyang 2 collaborations

Kathryn A Eaton 2 collaborations

Samuel Refetoff 2 collaborations

Yang-Yang Feng 1 collaboration

Miao Tang 1 collaboration

Mitsuhiro Suzuki 1 collaboration

Chinthika Gunasekara 1 collaboration

Yuki Anbe 1 collaboration

Yuichi Hiraoka 1 collaboration

Jun Liu 1 collaboration

Mamoru Ohkita 1 collaboration

Yasuo Matsumura 1 collaboration

Ji-Yang Wang 1 collaboration

Takeshi Tsubata 1 collaboration

Feng Gu 1 collaboration

Aileen Krüger 1 collaboration

Hannes G Roggenkamp 1 collaboration

Rick Alpers 1 collaboration

Dmitri Lodygin 1 collaboration

Vincent Jaquet 1 collaboration

Franziska Möckl 1 collaboration

Lola C Hernandez C 1 collaboration

Kai Winterberg 1 collaboration

Andreas Bauche 1 collaboration

Anette Rosche 1 collaboration

Daniel Schetelig 1 collaboration

René Werner 1 collaboration

Katrin Schröder 1 collaboration

Michael Carty 1 collaboration

Andrew G Bowie 1 collaboration

Samuel Huber 1 collaboration

Chris Meier 1 collaboration

Hans-Willi Mittrücker 1 collaboration

Joerg Heeren 1 collaboration

Karl-Heinz Krause 1 collaboration

Alexander Flügel 1 collaboration

Björn-Philipp Diercks 1 collaboration

Andreas H Guse 1 collaboration

S Bishu 1 collaboration

G Hou 1 collaboration

M El Zaatari 1 collaboration

S R Bishu 1 collaboration

D Popke 1 collaboration

M Zhang 1 collaboration

H Grasberger 1 collaboration

W Zou 1 collaboration

R W Stidham 1 collaboration

P D R Higgins 1 collaboration

J R Spence 1 collaboration

N Kamada 1 collaboration

J Y Kao 1 collaboration

Andrew T Magis 1 collaboration

Elisa Sheng 1 collaboration

Matthew P Conomos 1 collaboration

Lea S Garzotto 1 collaboration

Yasutada Akiba 1 collaboration

Jonathan Kaunitz 1 collaboration

Yael Haberman 1 collaboration

Subra Kugathasan 1 collaboration

Lee A Denson 1 collaboration

Gilbert S Omenn 1 collaboration

Mohammed El Zaatari 1 collaboration

Nicole Bowers 1 collaboration

Jami Kinnucan 1 collaboration

Beth Manoogian 1 collaboration

Michelle Muza-Moons 1 collaboration

Charlie Bourque 1 collaboration

Weiping Zou 1 collaboration

Peter D R Higgins 1 collaboration

Jason R Spence 1 collaboration

Henry Haley 1 collaboration

Brock Humphries 1 collaboration

Li-Jyun Syu 1 collaboration

Andrzej A Dlugosz 1 collaboration

Kathy Luker 1 collaboration

Gary D Luker 1 collaboration

Kathryn Eaton 1 collaboration

Marilia Cascalho 1 collaboration

Jinzhi Duan 1 collaboration

Juan D Matute 1 collaboration

Lukas W Unger 1 collaboration

Thomas Hanley 1 collaboration

Alexandra Schnell 1 collaboration

Xi Lin 1 collaboration

Niklas Krupka 1 collaboration

Paul Griebel 1 collaboration

Conner Lambden 1 collaboration

Brandon Sit 1 collaboration

Joep Grootjans 1 collaboration

Michal Pyzik 1 collaboration

Felix Sommer 1 collaboration

Sina Kaiser 1 collaboration

Maren Falk-Paulsen 1 collaboration

Tobias Fuhrer 1 collaboration

Hai Li 1 collaboration

Donggi Paik 1 collaboration

Yunjin Lee 1 collaboration

Jonathan N Glickman 1 collaboration

Adrienne W Paton 1 collaboration

Lynn Bry 1 collaboration

James C Paton 1 collaboration

Uwe Sauer 1 collaboration

Andrew J Macpherson 1 collaboration

Philip Rosenstiel 1 collaboration

Vijay K Kuchroo 1 collaboration

Matthew K Waldor 1 collaboration

Jun R Huh 1 collaboration

Arthur Kaser 1 collaboration

Richard S Blumberg 1 collaboration

Christopher J Alteri 1 collaboration

Michael Rodrigues 1 collaboration

Kohei Sugihara 1 collaboration

Stephanie D Himpsl 1 collaboration

Malak Bazzi 1 collaboration

Mao Miyoshi 1 collaboration

Tatsuki Nishioka 1 collaboration

Tina L Morhardt 1 collaboration

Peter Kuffa 1 collaboration

Chiharu Ishii 1 collaboration

Akiyoshi Hirayama 1 collaboration

Belgin Dogan 1 collaboration

Kenneth W Simpson 1 collaboration

Naohiro Inohara 1 collaboration

Harry L T Mobley 1 collaboration

Shinji Fukuda 1 collaboration

Nicolas Barnich 1 collaboration

Kun-Der Lin 1 collaboration

Guei-Fen Chiu 1 collaboration

Akbar K Waljee 1 collaboration

Deng-Chyang Wu 1 collaboration

Krystal D Kao 1 collaboration

Alexandra M Dumitrescu 1 collaboration

Xiao-Hui Liao 1 collaboration

Elliott G Swanson 1 collaboration

Roy E Weiss 1 collaboration

Panudda Srichomkwun 1 collaboration

Theodora Pappa 1 collaboration

Junfeng Chen 1 collaboration

Takashi Yoshimura 1 collaboration

Phillip Hoffmann 1 collaboration

Monica Malheiros França 1 collaboration

Rebecca Tagett 1 collaboration

Kazumichi Onigata 1 collaboration

Sabine Costagliola 1 collaboration

Jane Ranchalis 1 collaboration

Mitchell R Vollger 1 collaboration

Andrew B Stergachis 1 collaboration

Jessica X Chong 1 collaboration

Michael J Bamshad 1 collaboration

Guillaume Smits 1 collaboration

Gilbert Vassart 1 collaboration