Conner Lambden

Affiliations

Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts, USA.

Publications (8)

Differentiated agonistic antibody targeting CD137 eradicates large tumors without hepatotoxicity.

JCI insight

Avec: Ugur Eskiocak , Wilson Guzman , Benjamin Wolf , Christine Cummings , Lauren Milling , Hsin-Jung Wu , Michael Ophir , Conner Lambden , Pearl Bakhru , Dana C Gilmore , Samantha Ottinger , Lucy Liu , William K McConaughy , Sunny Q He , Chao Wang , Cheuk Lun Leung , Jason Lajoie , William F Carson , Nora Zizlsperger , Michael M Schmidt , Ana C Anderson , Piotr Bobrowicz , Thomas J Schuetz , Robert Tighe

Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut.

Immunity

Avec: Jinzhi Duan , Juan D Matute , Lukas W Unger , Thomas Hanley , Alexandra Schnell , Xi Lin , Niklas Krupka , Paul Griebel , Conner Lambden , Brandon Sit , Joep Grootjans , Michal Pyzik , Felix Sommer , Sina Kaiser , Maren Falk-Paulsen , Helmut Grasberger , John Y Kao , Tobias Fuhrer , Hai Li , Donggi Paik , Yunjin Lee , Samuel Refetoff , Jonathan N Glickman , Adrienne W Paton , Lynn Bry , James C Paton , Uwe Sauer , Andrew J Macpherson , Philip Rosenstiel , Vijay K Kuchroo , Matthew K Waldor , Jun R Huh , Arthur Kaser , Richard S Blumberg

An IL-27-Driven Transcriptional Network Identifies Regulators of IL-10 Expression across T Helper Cell Subsets.

Cell reports

Avec: Huiyuan Zhang , Asaf Madi , Nir Yosef , Norio Chihara , Amit Awasthi , Caroline Pot , Conner Lambden , Amitabh Srivastava , Patrick R Burkett , Jackson Nyman , Elena Christian , Yasaman Etminan , Annika Lee , Helene Stroh , Junrong Xia , Katarzyna Karwacz , Pratiksha I Thakore , Nandini Acharya , Alexandra Schnell , Chao Wang , Lionel Apetoh , Orit Rozenblatt-Rosen , Ana C Anderson , Aviv Regev , Vijay K Kuchroo

Calcitonin Gene-Related Peptide Negatively Regulates Alarmin-Driven Type 2 Innate Lymphoid Cell Responses.

Immunity

Avec: Antonia Wallrapp , Patrick R Burkett , Samantha J Riesenfeld , Se-Jin Kim , Elena Christian , Raja-Elie E Abdulnour , Pratiksha I Thakore , Alexandra Schnell , Conner Lambden , Rebecca H Herbst , Pavana Khan , Kazutake Tsujikawa , Ramnik J Xavier , Isaac M Chiu , Bruce D Levy , Aviv Regev , Vijay K Kuchroo

Tim-3 adapter protein Bat3 acts as an endogenous regulator of tolerogenic dendritic cell function.

Science immunology

Avec: Ruihan Tang , Nandini Acharya , Ayshwarya Subramanian , Vinee Purohit , Marcin Tabaka , Yu Hou , Danyang He , Karen O Dixon , Connor Lambden , Junrong Xia , Orit Rozenblatt-Rosen , Raymond A Sobel , Chao Wang , Aviv Regev , Ana C Anderson , Vijay K Kuchroo

Pan-cancer mapping of single CD8

Cell reports. Medicine

Avec: Katherine Tooley , Livnat Jerby , Giulia Escobar , S Harsha Krovi , Davide Mangani , Gitanjali Dandekar , Hanning Cheng , Asaf Madi , Ella Goldschmidt , Conner Lambden , Rajesh K Krishnan , Orit Rozenblatt-Rosen , Aviv Regev , Ana C Anderson

Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment.

Nature genetics

Avec: William L Hwang , Karthik A Jagadeesh , Jimmy A Guo , Hannah I Hoffman , Payman Yadollahpour , Jason W Reeves , Rahul Mohan , Eugene Drokhlyansky , Nicholas Van Wittenberghe , Orr Ashenberg , Samouil L Farhi , Denis Schapiro , Prajan Divakar , Eric Miller , Daniel R Zollinger , George Eng , Jason M Schenkel , Jennifer Su , Carina Shiau , Patrick Yu , William A Freed-Pastor , Domenic Abbondanza , Arnav Mehta , Joshua Gould , Conner Lambden , Caroline B M Porter , Alexander Tsankov , Danielle Dionne , Julia Waldman , Michael S Cuoco , Lan Nguyen , Toni Delorey , Devan Phillips , Jaimie L Barth , Marina Kem , Clifton Rodrigues , Debora Ciprani , Jorge Roldan , Piotr Zelga , Vjola Jorgji , Jonathan H Chen , Zackery Ely , Daniel Zhao , Kit Fuhrman , Robin Fropf , Joseph M Beechem , Jay S Loeffler , David P Ryan , Colin D Weekes , Cristina R Ferrone , Motaz Qadan , Martin J Aryee , Rakesh K Jain , Donna S Neuberg , Jennifer Y Wo , Theodore S Hong , Ramnik Xavier , Andrew J Aguirre , Orit Rozenblatt-Rosen , Mari Mino-Kenudson , Carlos Fernandez-Del Castillo , Andrew S Liss , David T Ting , Tyler Jacks , Aviv Regev

Neuropeptide signalling orchestrates T cell differentiation.

Nature

Avec: Yu Hou , Linyu Sun , Martin W LaFleur , Linglin Huang , Conner Lambden , Pratiksha I Thakore , Kathryn Geiger-Schuller , Kimitoshi Kimura , Longjun Yan , Yue Zang , Ruihan Tang , Jingwen Shi , Rocky Barilla , Liwen Deng , Ayshwarya Subramanian , Antonia Wallrapp , Hee Sun Choi , Yoon-Chul Kye , Orr Ashenberg , Geoffrey Schiebinger , John G Doench , Isaac M Chiu , Aviv Regev , Arlene H Sharpe , Vijay K Kuchroo

Réseau de co-auteurs

Aviv Regev 6 collaborations

Vijay K Kuchroo 5 collaborations

Ana C Anderson 4 collaborations

Orit Rozenblatt-Rosen 4 collaborations

Chao Wang 3 collaborations

Alexandra Schnell 3 collaborations

Pratiksha I Thakore 3 collaborations

Asaf Madi 2 collaborations

Patrick R Burkett 2 collaborations

Elena Christian 2 collaborations

Junrong Xia 2 collaborations

Nandini Acharya 2 collaborations

Antonia Wallrapp 2 collaborations

Isaac M Chiu 2 collaborations

Ruihan Tang 2 collaborations

Ayshwarya Subramanian 2 collaborations

Yu Hou 2 collaborations

Orr Ashenberg 2 collaborations

Ugur Eskiocak 1 collaboration

Wilson Guzman 1 collaboration

Benjamin Wolf 1 collaboration

Christine Cummings 1 collaboration

Lauren Milling 1 collaboration

Hsin-Jung Wu 1 collaboration

Michael Ophir 1 collaboration

Pearl Bakhru 1 collaboration

Dana C Gilmore 1 collaboration

Samantha Ottinger 1 collaboration

Lucy Liu 1 collaboration

William K McConaughy 1 collaboration

Sunny Q He 1 collaboration

Cheuk Lun Leung 1 collaboration

Jason Lajoie 1 collaboration

William F Carson 1 collaboration

Nora Zizlsperger 1 collaboration

Michael M Schmidt 1 collaboration

Piotr Bobrowicz 1 collaboration

Thomas J Schuetz 1 collaboration

Robert Tighe 1 collaboration

Jinzhi Duan 1 collaboration

Juan D Matute 1 collaboration

Lukas W Unger 1 collaboration

Thomas Hanley 1 collaboration

Xi Lin 1 collaboration

Niklas Krupka 1 collaboration

Paul Griebel 1 collaboration

Brandon Sit 1 collaboration

Joep Grootjans 1 collaboration

Michal Pyzik 1 collaboration

Felix Sommer 1 collaboration

Sina Kaiser 1 collaboration

Maren Falk-Paulsen 1 collaboration

Helmut Grasberger 1 collaboration

John Y Kao 1 collaboration

Tobias Fuhrer 1 collaboration

Hai Li 1 collaboration

Donggi Paik 1 collaboration

Yunjin Lee 1 collaboration

Samuel Refetoff 1 collaboration

Jonathan N Glickman 1 collaboration

Adrienne W Paton 1 collaboration

Lynn Bry 1 collaboration

James C Paton 1 collaboration

Uwe Sauer 1 collaboration

Andrew J Macpherson 1 collaboration

Philip Rosenstiel 1 collaboration

Matthew K Waldor 1 collaboration

Jun R Huh 1 collaboration

Arthur Kaser 1 collaboration

Richard S Blumberg 1 collaboration

Huiyuan Zhang 1 collaboration

Nir Yosef 1 collaboration

Norio Chihara 1 collaboration

Amit Awasthi 1 collaboration

Caroline Pot 1 collaboration

Amitabh Srivastava 1 collaboration

Jackson Nyman 1 collaboration

Yasaman Etminan 1 collaboration

Annika Lee 1 collaboration

Helene Stroh 1 collaboration

Katarzyna Karwacz 1 collaboration

Lionel Apetoh 1 collaboration

Samantha J Riesenfeld 1 collaboration

Se-Jin Kim 1 collaboration

Raja-Elie E Abdulnour 1 collaboration

Rebecca H Herbst 1 collaboration

Pavana Khan 1 collaboration

Kazutake Tsujikawa 1 collaboration

Ramnik J Xavier 1 collaboration

Bruce D Levy 1 collaboration

Vinee Purohit 1 collaboration

Marcin Tabaka 1 collaboration

Danyang He 1 collaboration

Karen O Dixon 1 collaboration

Connor Lambden 1 collaboration

Raymond A Sobel 1 collaboration

Katherine Tooley 1 collaboration

Livnat Jerby 1 collaboration

Giulia Escobar 1 collaboration

S Harsha Krovi 1 collaboration

Davide Mangani 1 collaboration

Gitanjali Dandekar 1 collaboration

Hanning Cheng 1 collaboration

Ella Goldschmidt 1 collaboration

Rajesh K Krishnan 1 collaboration

William L Hwang 1 collaboration

Karthik A Jagadeesh 1 collaboration

Jimmy A Guo 1 collaboration

Hannah I Hoffman 1 collaboration

Payman Yadollahpour 1 collaboration

Jason W Reeves 1 collaboration

Rahul Mohan 1 collaboration

Eugene Drokhlyansky 1 collaboration

Nicholas Van Wittenberghe 1 collaboration

Samouil L Farhi 1 collaboration

Denis Schapiro 1 collaboration

Prajan Divakar 1 collaboration

Eric Miller 1 collaboration

Daniel R Zollinger 1 collaboration

George Eng 1 collaboration

Jason M Schenkel 1 collaboration

Jennifer Su 1 collaboration

Carina Shiau 1 collaboration

Patrick Yu 1 collaboration

William A Freed-Pastor 1 collaboration

Domenic Abbondanza 1 collaboration

Arnav Mehta 1 collaboration

Joshua Gould 1 collaboration

Caroline B M Porter 1 collaboration

Alexander Tsankov 1 collaboration

Danielle Dionne 1 collaboration

Julia Waldman 1 collaboration

Michael S Cuoco 1 collaboration

Lan Nguyen 1 collaboration

Toni Delorey 1 collaboration

Devan Phillips 1 collaboration

Jaimie L Barth 1 collaboration

Marina Kem 1 collaboration

Clifton Rodrigues 1 collaboration

Debora Ciprani 1 collaboration

Jorge Roldan 1 collaboration

Piotr Zelga 1 collaboration

Vjola Jorgji 1 collaboration

Jonathan H Chen 1 collaboration

Zackery Ely 1 collaboration

Daniel Zhao 1 collaboration

Kit Fuhrman 1 collaboration

Robin Fropf 1 collaboration

Joseph M Beechem 1 collaboration

Jay S Loeffler 1 collaboration

David P Ryan 1 collaboration

Colin D Weekes 1 collaboration

Cristina R Ferrone 1 collaboration

Motaz Qadan 1 collaboration

Martin J Aryee 1 collaboration

Rakesh K Jain 1 collaboration

Donna S Neuberg 1 collaboration

Jennifer Y Wo 1 collaboration

Theodore S Hong 1 collaboration

Ramnik Xavier 1 collaboration

Andrew J Aguirre 1 collaboration

Mari Mino-Kenudson 1 collaboration

Carlos Fernandez-Del Castillo 1 collaboration

Andrew S Liss 1 collaboration

David T Ting 1 collaboration

Tyler Jacks 1 collaboration

Linyu Sun 1 collaboration

Martin W LaFleur 1 collaboration

Linglin Huang 1 collaboration

Kathryn Geiger-Schuller 1 collaboration

Kimitoshi Kimura 1 collaboration

Longjun Yan 1 collaboration

Yue Zang 1 collaboration

Jingwen Shi 1 collaboration

Rocky Barilla 1 collaboration

Liwen Deng 1 collaboration

Hee Sun Choi 1 collaboration

Yoon-Chul Kye 1 collaboration

Geoffrey Schiebinger 1 collaboration

John G Doench 1 collaboration

Arlene H Sharpe 1 collaboration