Michal Pyzik

Affiliations

Division of Gastroenterology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

ORCID: 0000-0003-2591-6202

Publications (9)

Embryonic macrophages function during early life to determine invariant natural killer T cell levels at barrier surfaces.

Nature immunology

Avec: Thomas Gensollen , Xi Lin , Ting Zhang , Michal Pyzik , Peter See , Jonathan N Glickman , Florent Ginhoux , Matthew Waldor , Marko Salmi , Pia Rantakari , Richard S Blumberg

FcRn is a CD32a coreceptor that determines susceptibility to IgG immune complex-driven autoimmunity.

The Journal of experimental medicine

Avec: Jonathan J Hubbard , Michal Pyzik , Timo Rath , Lisa K Kozicky , Kine M K Sand , Amit K Gandhi , Algirdas Grevys , Stian Foss , Susan C Menzies , Jonathan N Glickman , Edda Fiebiger , Derry C Roopenian , Inger Sandlie , Jan Terje Andersen , Laura M Sly , Kristi Baker , Richard S Blumberg

FcRn augments induction of tissue factor activity by IgG-containing immune complexes.

Blood

Avec: Douglas B Cines , Sergei Zaitsev , Lubica Rauova , Ann H Rux , Victoria Stepanova , Sriram Krishnaswamy , Amrita Sarkar , M Anna Kowalska , Guohua Zhao , Alan E Mast , Laurence J Blumberg , Keith R McCrae , Mortimer Poncz , Jonathan J Hubbard , Michal Pyzik , Richard S Blumberg

Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut.

Immunity

Avec: Jinzhi Duan , Juan D Matute , Lukas W Unger , Thomas Hanley , Alexandra Schnell , Xi Lin , Niklas Krupka , Paul Griebel , Conner Lambden , Brandon Sit , Joep Grootjans , Michal Pyzik , Felix Sommer , Sina Kaiser , Maren Falk-Paulsen , Helmut Grasberger , John Y Kao , Tobias Fuhrer , Hai Li , Donggi Paik , Yunjin Lee , Samuel Refetoff , Jonathan N Glickman , Adrienne W Paton , Lynn Bry , James C Paton , Uwe Sauer , Andrew J Macpherson , Philip Rosenstiel , Vijay K Kuchroo , Matthew K Waldor , Jun R Huh , Arthur Kaser , Richard S Blumberg

Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex-mediated immune responses.

Science advances

Avec: L J Blumberg , J E Humphries , S D Jones , L B Pearce , R Holgate , A Hearn , J Cheung , A Mahmood , B Del Tito , J S Graydon , L E Stolz , A Bitonti , S Purohit , D de Graaf , K Kacena , J T Andersen , G J Christianson , D C Roopenian , J J Hubbard , A K Gandhi , K Lasseter , M Pyzik , R S Blumberg

The Neonatal Fc Receptor (FcRn): A Misnomer?

Frontiers in immunology

Avec: Michal Pyzik , Kine M K Sand , Jonathan J Hubbard , Jan Terje Andersen , Inger Sandlie , Richard S Blumberg

Estimating probabilistic context-free grammars for proteins using contact map constraints.

PeerJ

Avec: Witold Dyrka , Mateusz Pyzik , François Coste , Hugo Talibart

Safety, Tolerability, and Activity of ALXN1830 Targeting the Neonatal Fc Receptor in Chronic Pemphigus.

The Journal of investigative dermatology

Avec: Victoria P Werth , Donna A Culton , Josef S S Concha , James S Graydon , Laurence J Blumberg , Joyce Okawa , Michal Pyzik , Richard S Blumberg , Russell P Hall

The therapeutic age of the neonatal Fc receptor.

Nature reviews. Immunology

Avec: Michal Pyzik , Lisa K Kozicky , Amit K Gandhi , Richard S Blumberg

Réseau de co-auteurs

Richard S Blumberg 7 collaborations

Jonathan N Glickman 3 collaborations

Jonathan J Hubbard 3 collaborations

Xi Lin 2 collaborations

Lisa K Kozicky 2 collaborations

Kine M K Sand 2 collaborations

Amit K Gandhi 2 collaborations

Inger Sandlie 2 collaborations

Jan Terje Andersen 2 collaborations

Laurence J Blumberg 2 collaborations

Thomas Gensollen 1 collaboration

Ting Zhang 1 collaboration

Peter See 1 collaboration

Florent Ginhoux 1 collaboration

Matthew Waldor 1 collaboration

Marko Salmi 1 collaboration

Pia Rantakari 1 collaboration

Timo Rath 1 collaboration

Algirdas Grevys 1 collaboration

Stian Foss 1 collaboration

Susan C Menzies 1 collaboration

Edda Fiebiger 1 collaboration

Derry C Roopenian 1 collaboration

Laura M Sly 1 collaboration

Kristi Baker 1 collaboration

Douglas B Cines 1 collaboration

Sergei Zaitsev 1 collaboration

Lubica Rauova 1 collaboration

Ann H Rux 1 collaboration

Victoria Stepanova 1 collaboration

Sriram Krishnaswamy 1 collaboration

Amrita Sarkar 1 collaboration

M Anna Kowalska 1 collaboration

Guohua Zhao 1 collaboration

Alan E Mast 1 collaboration

Keith R McCrae 1 collaboration

Mortimer Poncz 1 collaboration

Jinzhi Duan 1 collaboration

Juan D Matute 1 collaboration

Lukas W Unger 1 collaboration

Thomas Hanley 1 collaboration

Alexandra Schnell 1 collaboration

Niklas Krupka 1 collaboration

Paul Griebel 1 collaboration

Conner Lambden 1 collaboration

Brandon Sit 1 collaboration

Joep Grootjans 1 collaboration

Felix Sommer 1 collaboration

Sina Kaiser 1 collaboration

Maren Falk-Paulsen 1 collaboration

Helmut Grasberger 1 collaboration

John Y Kao 1 collaboration

Tobias Fuhrer 1 collaboration

Hai Li 1 collaboration

Donggi Paik 1 collaboration

Yunjin Lee 1 collaboration

Samuel Refetoff 1 collaboration

Adrienne W Paton 1 collaboration

Lynn Bry 1 collaboration

James C Paton 1 collaboration

Uwe Sauer 1 collaboration

Andrew J Macpherson 1 collaboration

Philip Rosenstiel 1 collaboration

Vijay K Kuchroo 1 collaboration

Matthew K Waldor 1 collaboration

Jun R Huh 1 collaboration

Arthur Kaser 1 collaboration

L J Blumberg 1 collaboration

J E Humphries 1 collaboration

S D Jones 1 collaboration

L B Pearce 1 collaboration

R Holgate 1 collaboration

A Hearn 1 collaboration

J Cheung 1 collaboration

A Mahmood 1 collaboration

B Del Tito 1 collaboration

J S Graydon 1 collaboration

L E Stolz 1 collaboration

A Bitonti 1 collaboration

S Purohit 1 collaboration

D de Graaf 1 collaboration

K Kacena 1 collaboration

J T Andersen 1 collaboration

G J Christianson 1 collaboration

D C Roopenian 1 collaboration

J J Hubbard 1 collaboration

A K Gandhi 1 collaboration

K Lasseter 1 collaboration

M Pyzik 1 collaboration

R S Blumberg 1 collaboration

Witold Dyrka 1 collaboration

Mateusz Pyzik 1 collaboration

François Coste 1 collaboration

Hugo Talibart 1 collaboration

Victoria P Werth 1 collaboration

Donna A Culton 1 collaboration

Josef S S Concha 1 collaboration

James S Graydon 1 collaboration

Joyce Okawa 1 collaboration

Russell P Hall 1 collaboration