Toni Delorey

Affiliations

Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142, USA; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.

Publications (10)

B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV.

Cell

Avec: Johannes F Scheid , Christopher O Barnes , Basak Eraslan , Andrew Hudak , Jennifer R Keeffe , Lisa A Cosimi , Eric M Brown , Frauke Muecksch , Yiska Weisblum , Shuting Zhang , Toni Delorey , Ann E Woolley , Fadi Ghantous , Sung-Moo Park , Devan Phillips , Betsabeh Tusi , Kathryn E Huey-Tubman , Alexander A Cohen , Priyanthi N P Gnanapragasam , Kara Rzasa , Theodora Hatziioanno , Michael A Durney , Xiebin Gu , Takuya Tada , Nathaniel R Landau , Anthony P West , Orit Rozenblatt-Rosen , Michael S Seaman , Lindsey R Baden , Daniel B Graham , Jacques Deguine , Paul D Bieniasz , Aviv Regev , Deborah Hung , Pamela J Bjorkman , Ramnik J Xavier

Induction of a colitogenic phenotype in Th1-like cells depends on interleukin-23 receptor signaling.

Immunity

Avec: Mathias Pawlak , David DeTomaso , Alexandra Schnell , Gerd Meyer Zu Horste , Youjin Lee , Jackson Nyman , Danielle Dionne , Brianna M L Regan , Vasundhara Singh , Toni Delorey , Markus A Schramm , Chao Wang , Antonia Wallrapp , Patrick R Burkett , Samantha J Riesenfeld , Ana C Anderson , Aviv Regev , Ramnik J Xavier , Nir Yosef , Vijay K Kuchroo

Spatially organized multicellular immune hubs in human colorectal cancer.

Cell

Avec: Karin Pelka , Matan Hofree , Jonathan H Chen , Siranush Sarkizova , Joshua D Pirl , Vjola Jorgji , Alborz Bejnood , Danielle Dionne , William H Ge , Katherine H Xu , Sherry X Chao , Daniel R Zollinger , David J Lieb , Jason W Reeves , Christopher A Fuhrman , Margaret L Hoang , Toni Delorey , Lan T Nguyen , Julia Waldman , Max Klapholz , Isaac Wakiro , Ofir Cohen , Julian Albers , Christopher S Smillie , Michael S Cuoco , Jingyi Wu , Mei-Ju Su , Jason Yeung , Brinda Vijaykumar , Angela M Magnuson , Natasha Asinovski , Tabea Moll , Max N Goder-Reiser , Anise S Applebaum , Lauren K Brais , Laura K DelloStritto , Sarah L Denning , Susannah T Phillips , Emma K Hill , Julia K Meehan , Dennie T Frederick , Tatyana Sharova , Abhay Kanodia , Ellen Z Todres , Judit Jané-Valbuena , Moshe Biton , Benjamin Izar , Conner D Lambden , Thomas E Clancy , Ronald Bleday , Nelya Melnitchouk , Jennifer Irani , Hiroko Kunitake , David L Berger , Amitabh Srivastava , Jason L Hornick , Shuji Ogino , Asaf Rotem , Sébastien Vigneau , Bruce E Johnson , Ryan B Corcoran , Arlene H Sharpe , Vijay K Kuchroo , Kimmie Ng , Marios Giannakis , Linda T Nieman , Genevieve M Boland , Andrew J Aguirre , Ana C Anderson , Orit Rozenblatt-Rosen , Aviv Regev , Nir Hacohen

Emergence of a High-Plasticity Cell State during Lung Cancer Evolution.

Cancer cell

Avec: Nemanja Despot Marjanovic , Matan Hofree , Jason E Chan , David Canner , Katherine Wu , Marianna Trakala , Griffin G Hartmann , Olivia C Smith , Jonathan Y Kim , Kelly Victoria Evans , Anna Hudson , Orr Ashenberg , Caroline B M Porter , Alborz Bejnood , Ayshwarya Subramanian , Kenneth Pitter , Yan Yan , Toni Delorey , Devan R Phillips , Nisargbhai Shah , Ojasvi Chaudhary , Alexander Tsankov , Travis Hollmann , Natasha Rekhtman , Pierre P Massion , John T Poirier , Linas Mazutis , Ruifang Li , Joo-Hyeon Lee , Angelika Amon , Charles M Rudin , Tyler Jacks , Aviv Regev , Tuomas Tammela

The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer.

Cancer cell

Avec: William A Freed-Pastor , Laurens J Lambert , Zackery A Ely , Nimisha B Pattada , Arjun Bhutkar , George Eng , Kim L Mercer , Ana P Garcia , Lin Lin , William M Rideout , William L Hwang , Jason M Schenkel , Alex M Jaeger , Roderick T Bronson , Peter M K Westcott , Tyler D Hether , Prajan Divakar , Jason W Reeves , Vikram Deshpande , Toni Delorey , Devan Phillips , Omer H Yilmaz , Aviv Regev , Tyler Jacks

Functional analyses and single cell immunoprofiling uncover sex-specific differences in SARS-CoV2 immune memory development.

Research square

Avec: Basak Eraslan , Eric Brown , Maura Benson , Liat Amir-Zilberstein , Sung-Moo Park , Betsabeh Tusi , Vladislav Pokatayev , Cody Hecht , Novalia Pishesha , Devan Phillips , Andy Kim , Shuting Zhang , Anthony Gaca , Fadi Ghantous , Toni Delorey , Jonathan Livny , Lindsey Baden , Orit Rozenblatt-Rosen , Daniel Graham , Aviv Regev , Michael Seaman , Ann Woolley , Lisa Cosimi , Deborah Hung , Jacques Deguine , Ramnik Xavier

Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment.

Nature genetics

Avec: William L Hwang , Karthik A Jagadeesh , Jimmy A Guo , Hannah I Hoffman , Payman Yadollahpour , Jason W Reeves , Rahul Mohan , Eugene Drokhlyansky , Nicholas Van Wittenberghe , Orr Ashenberg , Samouil L Farhi , Denis Schapiro , Prajan Divakar , Eric Miller , Daniel R Zollinger , George Eng , Jason M Schenkel , Jennifer Su , Carina Shiau , Patrick Yu , William A Freed-Pastor , Domenic Abbondanza , Arnav Mehta , Joshua Gould , Conner Lambden , Caroline B M Porter , Alexander Tsankov , Danielle Dionne , Julia Waldman , Michael S Cuoco , Lan Nguyen , Toni Delorey , Devan Phillips , Jaimie L Barth , Marina Kem , Clifton Rodrigues , Debora Ciprani , Jorge Roldan , Piotr Zelga , Vjola Jorgji , Jonathan H Chen , Zackery Ely , Daniel Zhao , Kit Fuhrman , Robin Fropf , Joseph M Beechem , Jay S Loeffler , David P Ryan , Colin D Weekes , Cristina R Ferrone , Motaz Qadan , Martin J Aryee , Rakesh K Jain , Donna S Neuberg , Jennifer Y Wo , Theodore S Hong , Ramnik Xavier , Andrew J Aguirre , Orit Rozenblatt-Rosen , Mari Mino-Kenudson , Carlos Fernandez-Del Castillo , Andrew S Liss , David T Ting , Tyler Jacks , Aviv Regev

Coordinated host-pathogen transcriptional dynamics revealed using sorted subpopulations and single macrophages infected with Candida albicans.

Nature communications

Avec: José F Muñoz , Toni Delorey , Christopher B Ford , Bi Yu Li , Dawn A Thompson , Reeta P Rao , Christina A Cuomo

Integrated multi-omics analyses reveal homology-directed repair pathway as a unique dependency in near-haploid leukemia.

Blood cancer journal

Avec: Yunpeng Liu-Lupo , James Dongjoo Ham , Swarna K A Jeewajee , Lan Nguyen , Toni Delorey , Azucena Ramos , David M Weinstock , Aviv Regev , Michael T Hemann

Systematically characterizing the roles of E3-ligase family members in inflammatory responses with massively parallel Perturb-seq.

bioRxiv : the preprint server for biology

Avec: Kathryn Geiger-Schuller , Basak Eraslan , Olena Kuksenko , Kushal K Dey , Karthik A Jagadeesh , Pratiksha I Thakore , Ozge Karayel , Andrea R Yung , Anugraha Rajagopalan , Ana M Meireles , Karren Dai Yang , Liat Amir-Zilberstein , Toni Delorey , Devan Phillips , Raktima Raychowdhury , Christine Moussion , Alkes L Price , Nir Hacohen , John G Doench , Caroline Uhler , Orit Rozenblatt-Rosen , Aviv Regev

Réseau de co-auteurs

Aviv Regev 9 collaborations

Devan Phillips 5 collaborations

Orit Rozenblatt-Rosen 5 collaborations

Basak Eraslan 3 collaborations

Danielle Dionne 3 collaborations

Jason W Reeves 3 collaborations

Tyler Jacks 3 collaborations

Shuting Zhang 2 collaborations

Fadi Ghantous 2 collaborations

Sung-Moo Park 2 collaborations

Betsabeh Tusi 2 collaborations

Jacques Deguine 2 collaborations

Deborah Hung 2 collaborations

Ramnik J Xavier 2 collaborations

Ana C Anderson 2 collaborations

Vijay K Kuchroo 2 collaborations

Matan Hofree 2 collaborations

Jonathan H Chen 2 collaborations

Vjola Jorgji 2 collaborations

Alborz Bejnood 2 collaborations

Daniel R Zollinger 2 collaborations

Julia Waldman 2 collaborations

Michael S Cuoco 2 collaborations

Andrew J Aguirre 2 collaborations

Nir Hacohen 2 collaborations

Orr Ashenberg 2 collaborations

Caroline B M Porter 2 collaborations

Alexander Tsankov 2 collaborations

William A Freed-Pastor 2 collaborations

George Eng 2 collaborations

William L Hwang 2 collaborations

Jason M Schenkel 2 collaborations

Prajan Divakar 2 collaborations

Liat Amir-Zilberstein 2 collaborations

Ramnik Xavier 2 collaborations

Karthik A Jagadeesh 2 collaborations

Lan Nguyen 2 collaborations

Johannes F Scheid 1 collaboration

Christopher O Barnes 1 collaboration

Andrew Hudak 1 collaboration

Jennifer R Keeffe 1 collaboration

Lisa A Cosimi 1 collaboration

Eric M Brown 1 collaboration

Frauke Muecksch 1 collaboration

Yiska Weisblum 1 collaboration

Ann E Woolley 1 collaboration

Kathryn E Huey-Tubman 1 collaboration

Alexander A Cohen 1 collaboration

Priyanthi N P Gnanapragasam 1 collaboration

Kara Rzasa 1 collaboration

Theodora Hatziioanno 1 collaboration

Michael A Durney 1 collaboration

Xiebin Gu 1 collaboration

Takuya Tada 1 collaboration

Nathaniel R Landau 1 collaboration

Anthony P West 1 collaboration

Michael S Seaman 1 collaboration

Lindsey R Baden 1 collaboration

Daniel B Graham 1 collaboration

Paul D Bieniasz 1 collaboration

Pamela J Bjorkman 1 collaboration

Mathias Pawlak 1 collaboration

David DeTomaso 1 collaboration

Alexandra Schnell 1 collaboration

Gerd Meyer Zu Horste 1 collaboration

Youjin Lee 1 collaboration

Jackson Nyman 1 collaboration

Brianna M L Regan 1 collaboration

Vasundhara Singh 1 collaboration

Markus A Schramm 1 collaboration

Chao Wang 1 collaboration

Antonia Wallrapp 1 collaboration

Patrick R Burkett 1 collaboration

Samantha J Riesenfeld 1 collaboration

Nir Yosef 1 collaboration

Karin Pelka 1 collaboration

Siranush Sarkizova 1 collaboration

Joshua D Pirl 1 collaboration

William H Ge 1 collaboration

Katherine H Xu 1 collaboration

Sherry X Chao 1 collaboration

David J Lieb 1 collaboration

Christopher A Fuhrman 1 collaboration

Margaret L Hoang 1 collaboration

Lan T Nguyen 1 collaboration

Max Klapholz 1 collaboration

Isaac Wakiro 1 collaboration

Ofir Cohen 1 collaboration

Julian Albers 1 collaboration

Christopher S Smillie 1 collaboration

Jingyi Wu 1 collaboration

Mei-Ju Su 1 collaboration

Jason Yeung 1 collaboration

Brinda Vijaykumar 1 collaboration

Angela M Magnuson 1 collaboration

Natasha Asinovski 1 collaboration

Tabea Moll 1 collaboration

Max N Goder-Reiser 1 collaboration

Anise S Applebaum 1 collaboration

Lauren K Brais 1 collaboration

Laura K DelloStritto 1 collaboration

Sarah L Denning 1 collaboration

Susannah T Phillips 1 collaboration

Emma K Hill 1 collaboration

Julia K Meehan 1 collaboration

Dennie T Frederick 1 collaboration

Tatyana Sharova 1 collaboration

Abhay Kanodia 1 collaboration

Ellen Z Todres 1 collaboration

Judit Jané-Valbuena 1 collaboration

Moshe Biton 1 collaboration

Benjamin Izar 1 collaboration

Conner D Lambden 1 collaboration

Thomas E Clancy 1 collaboration

Ronald Bleday 1 collaboration

Nelya Melnitchouk 1 collaboration

Jennifer Irani 1 collaboration

Hiroko Kunitake 1 collaboration

David L Berger 1 collaboration

Amitabh Srivastava 1 collaboration

Jason L Hornick 1 collaboration

Shuji Ogino 1 collaboration

Asaf Rotem 1 collaboration

Sébastien Vigneau 1 collaboration

Bruce E Johnson 1 collaboration

Ryan B Corcoran 1 collaboration

Arlene H Sharpe 1 collaboration

Kimmie Ng 1 collaboration

Marios Giannakis 1 collaboration

Linda T Nieman 1 collaboration

Genevieve M Boland 1 collaboration

Nemanja Despot Marjanovic 1 collaboration

Jason E Chan 1 collaboration

David Canner 1 collaboration

Katherine Wu 1 collaboration

Marianna Trakala 1 collaboration

Griffin G Hartmann 1 collaboration

Olivia C Smith 1 collaboration

Jonathan Y Kim 1 collaboration

Kelly Victoria Evans 1 collaboration

Anna Hudson 1 collaboration

Ayshwarya Subramanian 1 collaboration

Kenneth Pitter 1 collaboration

Yan Yan 1 collaboration

Devan R Phillips 1 collaboration

Nisargbhai Shah 1 collaboration

Ojasvi Chaudhary 1 collaboration

Travis Hollmann 1 collaboration

Natasha Rekhtman 1 collaboration

Pierre P Massion 1 collaboration

John T Poirier 1 collaboration

Linas Mazutis 1 collaboration

Ruifang Li 1 collaboration

Joo-Hyeon Lee 1 collaboration

Angelika Amon 1 collaboration

Charles M Rudin 1 collaboration

Tuomas Tammela 1 collaboration

Laurens J Lambert 1 collaboration

Zackery A Ely 1 collaboration

Nimisha B Pattada 1 collaboration

Arjun Bhutkar 1 collaboration

Kim L Mercer 1 collaboration

Ana P Garcia 1 collaboration

Lin Lin 1 collaboration

William M Rideout 1 collaboration

Alex M Jaeger 1 collaboration

Roderick T Bronson 1 collaboration

Peter M K Westcott 1 collaboration

Tyler D Hether 1 collaboration

Vikram Deshpande 1 collaboration

Omer H Yilmaz 1 collaboration

Eric Brown 1 collaboration

Maura Benson 1 collaboration

Vladislav Pokatayev 1 collaboration

Cody Hecht 1 collaboration

Novalia Pishesha 1 collaboration

Andy Kim 1 collaboration

Anthony Gaca 1 collaboration

Jonathan Livny 1 collaboration

Lindsey Baden 1 collaboration

Daniel Graham 1 collaboration

Michael Seaman 1 collaboration

Ann Woolley 1 collaboration

Lisa Cosimi 1 collaboration

Jimmy A Guo 1 collaboration

Hannah I Hoffman 1 collaboration

Payman Yadollahpour 1 collaboration

Rahul Mohan 1 collaboration

Eugene Drokhlyansky 1 collaboration

Nicholas Van Wittenberghe 1 collaboration

Samouil L Farhi 1 collaboration

Denis Schapiro 1 collaboration

Eric Miller 1 collaboration

Jennifer Su 1 collaboration

Carina Shiau 1 collaboration

Patrick Yu 1 collaboration

Domenic Abbondanza 1 collaboration

Arnav Mehta 1 collaboration

Joshua Gould 1 collaboration

Conner Lambden 1 collaboration

Jaimie L Barth 1 collaboration

Marina Kem 1 collaboration

Clifton Rodrigues 1 collaboration

Debora Ciprani 1 collaboration

Jorge Roldan 1 collaboration

Piotr Zelga 1 collaboration

Zackery Ely 1 collaboration

Daniel Zhao 1 collaboration

Kit Fuhrman 1 collaboration

Robin Fropf 1 collaboration

Joseph M Beechem 1 collaboration

Jay S Loeffler 1 collaboration

David P Ryan 1 collaboration

Colin D Weekes 1 collaboration

Cristina R Ferrone 1 collaboration

Motaz Qadan 1 collaboration

Martin J Aryee 1 collaboration

Rakesh K Jain 1 collaboration

Donna S Neuberg 1 collaboration

Jennifer Y Wo 1 collaboration

Theodore S Hong 1 collaboration

Mari Mino-Kenudson 1 collaboration

Carlos Fernandez-Del Castillo 1 collaboration

Andrew S Liss 1 collaboration

David T Ting 1 collaboration

José F Muñoz 1 collaboration

Christopher B Ford 1 collaboration

Bi Yu Li 1 collaboration

Dawn A Thompson 1 collaboration

Reeta P Rao 1 collaboration

Christina A Cuomo 1 collaboration

Yunpeng Liu-Lupo 1 collaboration

James Dongjoo Ham 1 collaboration

Swarna K A Jeewajee 1 collaboration

Azucena Ramos 1 collaboration

David M Weinstock 1 collaboration

Michael T Hemann 1 collaboration

Kathryn Geiger-Schuller 1 collaboration

Olena Kuksenko 1 collaboration

Kushal K Dey 1 collaboration

Pratiksha I Thakore 1 collaboration

Ozge Karayel 1 collaboration

Andrea R Yung 1 collaboration

Anugraha Rajagopalan 1 collaboration

Ana M Meireles 1 collaboration

Karren Dai Yang 1 collaboration

Raktima Raychowdhury 1 collaboration

Christine Moussion 1 collaboration

Alkes L Price 1 collaboration

John G Doench 1 collaboration

Caroline Uhler 1 collaboration