Marilia Cascalho

Affiliations

Department of Surgery, University of Michigan, Ann Arbor, MI, United States.
Department of Microbiology & Immunology, University of Michigan, Ann Arbor, MI, United States.

Publications (27)

Human Ovarian Follicles Xenografted in Immunoisolating Capsules Survive Long Term Implantation in Mice.

Frontiers in endocrinology

Avec: Margaret A Brunette , Hadrian M Kinnear , Prianka H Hashim , Colleen L Flanagan , James R Day , Marilia Cascalho , Vasantha Padmanabhan , Ariella Shikanov

The role of B cell immunity in VCA graft rejection and acceptance.

Human immunology

Avec: Christina L Kaufman , Marilia Cascalho , Tuna Ozyurekoglu , Christopher M Jones , Allan Ramirez , Tiffany Roberts , Huey Y Tien , Rodrigo Moreno , Elkin Galvis , Tsu-Min Tsai , Michelle Palazzo , Scott Farner , Jeffrey L Platt

A Combination Adjuvant for the Induction of Potent Antiviral Immune Responses for a Recombinant SARS-CoV-2 Protein Vaccine.

Frontiers in immunology

Avec: Sonia Jangra , Jeffrey J Landers , Raveen Rathnasinghe , Jessica J O'Konek , Katarzyna W Janczak , Marilia Cascalho , Andrew A Kennedy , Andrew W Tai , James R Baker , Michael Schotsaert , Pamela T Wong

Differential inflammatory responses of the native left and right ventricle associated with donor heart preservation.

Physiological reports

Avec: Ienglam Lei , Wei Huang , Peter A Ward , Jordan S Pober , George Tellides , Gorav Ailawadi , Francis D Pagani , Andrew P Landstrom , Zhong Wang , Richard M Mortensen , Marilia Cascalho , Jeffrey Platt , Yuqing Eugene Chen , Hugo Yu Kor Lam , Paul C Tang

The five dimensions of B cell tolerance.

Immunological reviews

Avec: Jeffrey L Platt , Mayara Garcia de Mattos Barbosa , Marilia Cascalho

Aim2-mediated/IFN-β-independent regulation of gastric metaplastic lesions via CD8+ T cells.

JCI insight

Avec: Mohamad El-Zaatari , Shrinivas Bishu , Min Zhang , Helmut Grasberger , Guoqing Hou , Henry Haley , Brock Humphries , Li-Jyun Syu , Andrzej A Dlugosz , Kathy Luker , Gary D Luker , Kathryn Eaton , Nobuhiko Kamada , Marilia Cascalho , John Y Kao

Engineered Multivalent Nanobodies Potently and Broadly Neutralize SARS-CoV-2 Variants.

Advanced therapeutics

Avec: Jennifer M Zupancic , John S Schardt , Alec A Desai , Emily K Makowski , Matthew D Smith , Ghasidit Pornnoppadol , Mayara Garcia de Mattos Barbosa , Marilia Cascalho , Thomas M Lanigan , Peter M Tessier

TNFRSF13B in B cell responses to organ transplantation.

Human immunology

Avec: Marilia Cascalho , Jeffrey L Platt

Metabolic reprogramming by immune-responsive gene 1 up-regulation improves donor heart preservation and function.

Science translational medicine

Avec: Ienglam Lei , Wei Huang , Pierre Emmanuel Noly , Suyash Naik , Miriyam Ghali , Liu Liu , Francis D Pagani , Ashraf Abou El Ela , Jordan S Pober , Bertram Pitt , Jeffrey L Platt , Marilia Cascalho , Zhong Wang , Y Eugene Chen , Richard M Mortensen , Paul C Tang

Complement C3d enables protective immunity capable of distinguishing spontaneously transformed from non-transformed cells.

bioRxiv : the preprint server for biology

Avec: Jeffrey L Platt , Chong Zhao , Jeffrey Chicca , Matthew J Pianko , Joshua Han , Stephanie The , Arvind Rao , Evan Keller , Mayara Garcia de Mattos Barbosa , Lwar Naing , Tracy Pasieka-Axenov , Lev Axenov , Simon Schaefer , Evan Farkash , Marilia Cascalho

Non-canonical B cell functions in transplantation.

Human immunology

Avec: Jeffrey L Platt , Marilia Cascalho

Cell Fusion in Malignancy: A Cause or Consequence? A Provocateur or Cure?

Cells

Avec: Jeffrey L Platt , Marilia Cascalho

TNFRSF13B polymorphisms counter microbial adaptation to enteric IgA.

JCI insight

Avec: Jeffrey L Platt , Mayara Garcia de Mattos Barbosa , Daniel Huynh , Adam R Lefferts , Juhi Katta , Cyra Kharas , Peter Freddolino , Christine M Bassis , Christiane Wobus , Raif Geha , Richard Bram , Gabriel Nunez , Nobuhiko Kamada , Marilia Cascalho

TNFRSF13B genotypes control immune-mediated pathology by regulating the functions of innate B cells.

JCI insight

Avec: Mayara Garcia de Mattos Barbosa , Adam R Lefferts , Daniel Huynh , Hui Liu , Yu Zhang , Beverly Fu , Jenna Barnes , Milagros Samaniego , Richard J Bram , Raif S Geha , Ariella Shikanov , Eline T Luning Prak , Evan A Farkash , Jeffrey L Platt , Marilia Cascalho

A non-human primate model of acute liver failure suitable for testing liver support systems.

Frontiers in medicine

Avec: Ranjeet S Kalsi , Alina Ostrowska , Adam Olson , Mubina Quader , Melvin Deutsch , Norma J Arbujas-Silva , Jen Symmonds , Alejandro Soto-Gutierrez , John J Crowley , Miguel Reyes-Mugica , Giselle Sanchez-Guerrero , Hartmut Jaeschke , Bruce P Amiot , Marilia Cascalho , Scott L Nyberg , Jeffrey L Platt , Edgar N Tafaleng , Ira J Fox

Accommodation in allogeneic and xenogeneic organ transplantation: Prevalence, impact, and implications for monitoring and for therapeutics.

Human immunology

Avec: Jeffrey L Platt , Marilia Cascalho

Encapsulated Allografts Preclude Host Sensitization and Promote Ovarian Endocrine Function in Ovariectomized Young Rhesus Monkeys and Sensitized Mice.

Bioengineering (Basel, Switzerland)

Avec: James R Day , Colleen L Flanagan , Anu David , Dennis J Hartigan-O'Connor , Mayara Garcia de Mattos Barbosa , Michele L Martinez , Charles Lee , Jenna Barnes , Evan Farkash , Mary Zelinski , Alice Tarantal , Marilia Cascalho , Ariella Shikanov

Effect of Donor Age on Endocrine Function of and Immune Response to Ovarian Grafts.

International journal of molecular sciences

Avec: Monica A Wall , Mayara Garcia de Mattos Barbosa , Natalie Hanby , Michelle M Cai , Margaret Brunette , Despina I Pavlidis , Paula Arrowsmith , Ansen Q Tan , Marilia Cascalho , Ariella Shikanov

Encapsulation of ovarian allograft precludes immune rejection and promotes restoration of endocrine function in immune-competent ovariectomized mice.

Scientific reports

Avec: James Ronald Day , Anu David , Mayara Garcia de Mattos Barbosa , Margaret Ann Brunette , Marilia Cascalho , Ariella Shikanov

Intestinal non-canonical NFκB signaling shapes the local and systemic immune response.

Nature communications

Avec: Sadeesh K Ramakrishnan , Huabing Zhang , Xiaoya Ma , Inkyung Jung , Andrew J Schwartz , Daniel Triner , Samantha N Devenport , Nupur K Das , Xiang Xue , Melody Y Zeng , Yinling Hu , Richard M Mortensen , Joel K Greenson , Marilia Cascalho , Christiane E Wobus , Justin A Colacino , Gabriel Nunez , Liangyou Rui , Yatrik M Shah

Frontiers in immunology

Avec: Marilia Cascalho , Jeffrey L Platt

IgV somatic mutation of human anti-SARS-CoV-2 monoclonal antibodies governs neutralization and breadth of reactivity.

JCI insight

Avec: Mayara Garcia de Mattos Barbosa , Hui Liu , Daniel Huynh , Greg Shelley , Evan T Keller , Brian T Emmer , Emily Sherman , David Ginsburg , Andrew A Kennedy , Andrew W Tai , Christiane Wobus , Carmen Mirabeli , Thomas M Lanigan , Milagros Samaniego , Wenzhao Meng , Aaron M Rosenfeld , Eline T Luning Prak , Jeffrey L Platt , Marilia Cascalho

A Combination Adjuvant for the Induction of Potent Antiviral Immune Responses for a Recombinant SARS-CoV-2 Protein Vaccine.

bioRxiv : the preprint server for biology

Discovery and characterization of high-affinity, potent SARS-CoV-2 neutralizing antibodies via single B cell screening.

Scientific reports

Avec: John S Schardt , Ghasidit Pornnoppadol , Alec A Desai , Kyung Soo Park , Jennifer M Zupancic , Emily K Makowski , Matthew D Smith , Hongwei Chen , Mayara Garcia de Mattos Barbosa , Marilia Cascalho , Thomas M Lanigan , James J Moon , Peter M Tessier

Directed evolution of potent neutralizing nanobodies against SARS-CoV-2 using CDR-swapping mutagenesis.

Cell chemical biology

Avec: Jennifer M Zupancic , Alec A Desai , John S Schardt , Ghasidit Pornnoppadol , Emily K Makowski , Matthew D Smith , Andrew A Kennedy , Mayara Garcia de Mattos Barbosa , Marilia Cascalho , Thomas M Lanigan , Andrew W Tai , Peter M Tessier

Somatic Cell Fusion in Host Defense and Adaptation.

Results and problems in cell differentiation

Avec: Jeffrey L Platt , Marilia Cascalho

Antigen-Clustered Nanovaccine Achieves Long-Term Tumor Remission by Promoting B/CD 4 T Cell Crosstalk.

ACS nano

Avec: Chengyi Li , Ryan Clauson , Luke F Bugada , Fang Ke , Bing He , Zhixin Yu , Hongwei Chen , Binyamin Jacobovitz , Hongxiang Hu , Polina Chuikov , Brett Dallas Hill , Syed M Rizvi , Yudong Song , Kai Sun , Pasieka Axenov , Daniel Huynh , Xinyi Wang , Lana Garmire , Yu Leo Lei , Irina Grigorova , Fei Wen , Marilia Cascalho , Wei Gao , Duxin Sun

Réseau de co-auteurs

Jeffrey L Platt 14 collaborations

Mayara Garcia de Mattos Barbosa 11 collaborations

Ariella Shikanov 5 collaborations

Andrew A Kennedy 4 collaborations

Andrew W Tai 4 collaborations

Thomas M Lanigan 4 collaborations

Daniel Huynh 4 collaborations

Richard M Mortensen 3 collaborations

Jennifer M Zupancic 3 collaborations

John S Schardt 3 collaborations

Alec A Desai 3 collaborations

Emily K Makowski 3 collaborations

Matthew D Smith 3 collaborations

Ghasidit Pornnoppadol 3 collaborations

Peter M Tessier 3 collaborations

Colleen L Flanagan 2 collaborations

James R Day 2 collaborations

Sonia Jangra 2 collaborations

Jeffrey J Landers 2 collaborations

Raveen Rathnasinghe 2 collaborations

Jessica J O'Konek 2 collaborations

Katarzyna W Janczak 2 collaborations

James R Baker 2 collaborations

Michael Schotsaert 2 collaborations

Pamela T Wong 2 collaborations

Ienglam Lei 2 collaborations

Wei Huang 2 collaborations

Jordan S Pober 2 collaborations

Francis D Pagani 2 collaborations

Zhong Wang 2 collaborations

Paul C Tang 2 collaborations

Nobuhiko Kamada 2 collaborations

Evan Farkash 2 collaborations

Adam R Lefferts 2 collaborations

Christiane Wobus 2 collaborations

Gabriel Nunez 2 collaborations

Hui Liu 2 collaborations

Jenna Barnes 2 collaborations

Milagros Samaniego 2 collaborations

Eline T Luning Prak 2 collaborations

Anu David 2 collaborations

Hongwei Chen 2 collaborations

Margaret A Brunette 1 collaboration

Hadrian M Kinnear 1 collaboration

Prianka H Hashim 1 collaboration

Vasantha Padmanabhan 1 collaboration

Christina L Kaufman 1 collaboration

Tuna Ozyurekoglu 1 collaboration

Christopher M Jones 1 collaboration

Allan Ramirez 1 collaboration

Tiffany Roberts 1 collaboration

Huey Y Tien 1 collaboration

Rodrigo Moreno 1 collaboration

Elkin Galvis 1 collaboration

Tsu-Min Tsai 1 collaboration

Michelle Palazzo 1 collaboration

Scott Farner 1 collaboration

Peter A Ward 1 collaboration

George Tellides 1 collaboration

Gorav Ailawadi 1 collaboration

Andrew P Landstrom 1 collaboration

Jeffrey Platt 1 collaboration

Yuqing Eugene Chen 1 collaboration

Hugo Yu Kor Lam 1 collaboration

Mohamad El-Zaatari 1 collaboration

Shrinivas Bishu 1 collaboration

Min Zhang 1 collaboration

Helmut Grasberger 1 collaboration

Guoqing Hou 1 collaboration

Henry Haley 1 collaboration

Brock Humphries 1 collaboration

Li-Jyun Syu 1 collaboration

Andrzej A Dlugosz 1 collaboration

Kathy Luker 1 collaboration

Gary D Luker 1 collaboration

Kathryn Eaton 1 collaboration

John Y Kao 1 collaboration

Pierre Emmanuel Noly 1 collaboration

Suyash Naik 1 collaboration

Miriyam Ghali 1 collaboration

Liu Liu 1 collaboration

Ashraf Abou El Ela 1 collaboration

Bertram Pitt 1 collaboration

Y Eugene Chen 1 collaboration

Chong Zhao 1 collaboration

Jeffrey Chicca 1 collaboration

Matthew J Pianko 1 collaboration

Joshua Han 1 collaboration

Stephanie The 1 collaboration

Arvind Rao 1 collaboration

Evan Keller 1 collaboration

Lwar Naing 1 collaboration

Tracy Pasieka-Axenov 1 collaboration

Lev Axenov 1 collaboration

Simon Schaefer 1 collaboration

Juhi Katta 1 collaboration

Cyra Kharas 1 collaboration

Peter Freddolino 1 collaboration

Christine M Bassis 1 collaboration

Raif Geha 1 collaboration

Richard Bram 1 collaboration

Yu Zhang 1 collaboration

Beverly Fu 1 collaboration

Richard J Bram 1 collaboration

Raif S Geha 1 collaboration

Evan A Farkash 1 collaboration

Ranjeet S Kalsi 1 collaboration

Alina Ostrowska 1 collaboration

Adam Olson 1 collaboration

Mubina Quader 1 collaboration

Melvin Deutsch 1 collaboration

Norma J Arbujas-Silva 1 collaboration

Jen Symmonds 1 collaboration

Alejandro Soto-Gutierrez 1 collaboration

John J Crowley 1 collaboration

Miguel Reyes-Mugica 1 collaboration

Giselle Sanchez-Guerrero 1 collaboration

Hartmut Jaeschke 1 collaboration

Bruce P Amiot 1 collaboration

Scott L Nyberg 1 collaboration

Edgar N Tafaleng 1 collaboration

Ira J Fox 1 collaboration

Dennis J Hartigan-O'Connor 1 collaboration

Michele L Martinez 1 collaboration

Charles Lee 1 collaboration

Mary Zelinski 1 collaboration

Alice Tarantal 1 collaboration

Monica A Wall 1 collaboration

Natalie Hanby 1 collaboration

Michelle M Cai 1 collaboration

Margaret Brunette 1 collaboration

Despina I Pavlidis 1 collaboration

Paula Arrowsmith 1 collaboration

Ansen Q Tan 1 collaboration

James Ronald Day 1 collaboration

Margaret Ann Brunette 1 collaboration

Sadeesh K Ramakrishnan 1 collaboration

Huabing Zhang 1 collaboration

Xiaoya Ma 1 collaboration

Inkyung Jung 1 collaboration

Andrew J Schwartz 1 collaboration

Daniel Triner 1 collaboration

Samantha N Devenport 1 collaboration

Nupur K Das 1 collaboration

Xiang Xue 1 collaboration

Melody Y Zeng 1 collaboration

Yinling Hu 1 collaboration

Joel K Greenson 1 collaboration

Christiane E Wobus 1 collaboration

Justin A Colacino 1 collaboration

Liangyou Rui 1 collaboration

Yatrik M Shah 1 collaboration

Greg Shelley 1 collaboration

Evan T Keller 1 collaboration

Brian T Emmer 1 collaboration

Emily Sherman 1 collaboration

David Ginsburg 1 collaboration

Carmen Mirabeli 1 collaboration

Wenzhao Meng 1 collaboration

Aaron M Rosenfeld 1 collaboration

Kyung Soo Park 1 collaboration

James J Moon 1 collaboration

Chengyi Li 1 collaboration

Ryan Clauson 1 collaboration

Luke F Bugada 1 collaboration

Fang Ke 1 collaboration

Bing He 1 collaboration

Zhixin Yu 1 collaboration

Binyamin Jacobovitz 1 collaboration

Hongxiang Hu 1 collaboration

Polina Chuikov 1 collaboration

Brett Dallas Hill 1 collaboration

Syed M Rizvi 1 collaboration

Yudong Song 1 collaboration

Kai Sun 1 collaboration

Pasieka Axenov 1 collaboration

Xinyi Wang 1 collaboration

Lana Garmire 1 collaboration

Yu Leo Lei 1 collaboration

Irina Grigorova 1 collaboration

Fei Wen 1 collaboration

Wei Gao 1 collaboration

Duxin Sun 1 collaboration