Patterns of infection following transrectal ultrasound-guided biopsy of the prostate in a regional New South Wales Centre.
Aged
Aged, 80 and over
Bacterial Infections
/ epidemiology
Humans
Image-Guided Biopsy
/ adverse effects
Male
Middle Aged
New South Wales
/ epidemiology
Patient Readmission
/ statistics & numerical data
Postoperative Complications
Prostate
/ pathology
Prostatic Neoplasms
/ diagnosis
Retrospective Studies
Ultrasonography, Interventional
/ adverse effects
antimicrobial resistance
elderly
older persons
prostate cancer
sepsis
Journal
The Australian journal of rural health
ISSN: 1440-1584
Titre abrégé: Aust J Rural Health
Pays: Australia
ID NLM: 9305903
Informations de publication
Date de publication:
Jun 2020
Jun 2020
Historique:
received:
02
12
2018
revised:
13
08
2019
accepted:
16
12
2019
pubmed:
2
6
2020
medline:
16
6
2021
entrez:
2
6
2020
Statut:
ppublish
Résumé
To determine the rates, severity and patterns of resistance in patients presenting with post-transrectal ultrasound infection in a regional centre in New South Wales, Australia. A single-centre retrospective review from August 2013 until August 2017. Murrumbidgee Local Health District, New South Wales. All patients who underwent transrectal ultrasonography biopsy of the prostate in the public health system. Rate of infection and sepsis following biopsy of the prostate requiring readmission to hospital within 30 days from the procedure. A total of 317 men underwent transrectal ultrasound-guided biopsy of the prostate over the study period. Nineteen (6%) patients presented with clinical signs of post-transrectal ultrasound infection, of which 18 (5.7%) required readmission for intravenous antibiotics. Median time to readmission was 2 days (0-7), and the average length of hospital stay was 5 days (1-15). Three (0.3%) patients required admission to intensive care for inotropic support. Thirteen patients (68%) had positive blood cultures, and all were positive for Escherichia coli. Four of these patients (21%) had extended spectrum beta-lactamase producing isolates resistant to their preoperative antibiotics. Prostate cancer is common in the elderly community with worse outcomes in regional settings. Infective complications from transrectal ultrasound biopsy were 6% in this regional setting with high rates of multi-resistant organisms. Awareness of this is important for rural health practitioners who are likely to be exposed to this patient population.
Types de publication
Journal Article
Langues
eng
Pagination
301-306Informations de copyright
© 2020 National Rural Health Alliance Ltd.
Références
Ferlay J, Soerjomataram I, Dikshit R, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer. 2015;136:359-386.
Cancer Council Australia. Prostate Cancer. Australia. https://www.cancer.org.au/about-cancer/types-of-cancer/prostate-cancer.html. Accessed December 2, 2018.
Huang T, Lin A, Chen K. Bacteriology profile of febrile infectious complications after transrectal ultrasound-guided prostate biopsy. Uro Sci. 2014;25:83-86.
Gilchrist B. The Murrumbidgee Local Health District 2018 Summary Population and Health Profile Population, Hospitalisation and Potentially Preventable Hospitalisations update, June 2018. https://www.mlhd.health.nsw.gov.au/getmedia/6dd77cb1-27e0-4fa2-afc0-48af0823e869/Report-Murrumbidgee-Summary-Health-and-Population-Profile. Accessed November 26, 2018.
Australian Bureau of Statistics. Regional Population by Age and Sex, Australia, 2017. http://www.abs.gov.au/ausstats/abs@.nsf/mf/3235.0. Accessed December 2, 2018.
Cancer Australia. Prostate cancer statistics. https://prostate-cancer.canceraustralia.gov.au/statistics. Accessed December 1, 2018.
Cancer Statistics NSW. Prostate Cancer Statistics. https://www.cancer.nsw.gov.au/cancer-statistics-nsw#/analysis/incidence/. Accessed December 2, 2018.
Levy M, Evans L, Rhodes A. The surviving sepsis Campaign bundle: 2018 update. Intensive Care Med. 2018;44(6):925-928.
Williamson D, Barrett L, Rogers B, et al. Infectious complications following transrectal ultrasound-guided prostate biopsy: new challenges in the era of multidrug-resistant Escherichia coli. Clinical infectious disease. 2013;57(2):267-274.
Australian Commission on Safety and Quality in Health Care (ACSQHC). AURA 2017: Second Australian Report on Antimicrobial Use and Resistance in Human Health. Sydney: ACSQHC; 2017.
Borghesi M, Ahmed N, Nam R, et al. Complications after systematic, random, and image-guided prostate biopsy. Eur Urol. 2016;71(3):353-365.
Harris P, Paterson D, Rogers B. Facing the challenge of multidrug resistant gram-negative bacilli in Australia. Med J Aust. 2015;202(5):243-246.
Patel U, Dasgupta P, Amoroso P, et al. Infection after transrectal ultrasonography-guided prostate biopsy: increased relative risks after recent international travel or antibiotic use. BJU Int. 2011;109(12):1781-1785.
Gummet J, Weerakoon M, Huang S, et al. Sepsis and ‘superbugs’: should we favour the transperineal over the transrectal approach for prostate biopsy? BJU Int. 2014;114(3):384-388.
Davis P, Paul E, Grummet J. Current practice of prostate biopsy in Australia and New Zealand: a survey. Urol Ann. 2015;7(3):315-319.