Hip Fracture Outcomes During the COVID-19 Pandemic: Early Results From New York.


Journal

Journal of orthopaedic trauma
ISSN: 1531-2291
Titre abrégé: J Orthop Trauma
Pays: United States
ID NLM: 8807705

Informations de publication

Date de publication:
08 2020
Historique:
pubmed: 3 6 2020
medline: 6 8 2020
entrez: 3 6 2020
Statut: ppublish

Résumé

To evaluate inpatient outcomes among patients with hip fracture treated during the COVID-19 pandemic in New York City. Multicenter retrospective cohort study. One Level 1 trauma center and one orthopaedic specialty hospital in New York City. Fifty-nine consecutive patients (average age 85 years, range: 65-100 years) treated for a hip fracture (OTA/AO 31, 32.1) over a 5-week period, March 20, 2020, to April 24, 2020, during the height of the COVID-19 crisis. COVID-19 infection status was used to stratify patients. The primary outcome was inpatient mortality. Secondary outcomes were admission to the intensive care unit, unexpected intubation, pneumonia, deep vein thrombosis, pulmonary embolus, myocardial infarction, cerebrovascular accident, urinary tract infection, and transfusion. Baseline demographics, comorbidities, treatment characteristics, and COVID-related symptomatology were also evaluated. Ten patients (15%) tested positive for COVID-19 (COVID+) (n = 9; 7 preoperatively and 2 postoperatively) or were presumed positive (n = 1), 40 (68%) patients tested negative, and 9 (15%) patients were not tested in the primary hospitalization. American Society of Anesthesiologists' scores were higher in the COVID+ group (d = -0.83; P = 0.04); however, the Charlson Comorbidity Index was similar between the study groups (d = -0.17; P = 0.63). Inpatient mortality was significantly increased in the COVID+ cohort (56% vs. 4%; odds ratio 30.0, 95% confidence interval 4.3-207; P = 0.001). Including the one presumed positive case in the COVID+ cohort increased this difference (60% vs. 2%; odds ratio 72.0, 95% confidence interval 7.9-754; P < 0.001). Hip fracture patients with concomitant COVID-19 infection had worse American Society of Anesthesiologists' scores but similar baseline comorbidities with significantly higher rates of inpatient mortality compared with those without concomitant COVID-19 infection. Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.

Identifiants

pubmed: 32482977
doi: 10.1097/BOT.0000000000001849
pmc: PMC7302077
pii: 00005131-202008000-00003
doi:

Types de publication

Evaluation Study Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

403-410

Références

BMJ. 2020 Mar 26;368:m1198
pubmed: 32217618
Intensive Care Med. 2020 May;46(5):846-848
pubmed: 32125452
J Bone Joint Surg Am. 2015 Aug 19;97(16):1333-9
pubmed: 26290084
Osteoporos Int. 2007 Dec;18(12):1583-93
pubmed: 17566814
J Bone Joint Surg Am. 2020 May 6;102(9):750-758
pubmed: 32379114
J Bone Joint Surg Am. 2020 Jun 3;102(11):946-950
pubmed: 32282412
Arthritis Rheumatol. 2017 Jun;69(6):1135-1143
pubmed: 28217930
J Orthop Trauma. 2020 Sep;34(9):469-475
pubmed: 32815833
Bone. 2016 May;86:119-30
pubmed: 26946132
Crit Care. 2017 Mar 21;21(1):67
pubmed: 28320449
J Bone Joint Surg Am. 2020 Jul 1;102(13):e69
pubmed: 32618917
PLoS Med. 2007 Oct 16;4(10):e296
pubmed: 17941714
Nature. 2020 Jun;582(7813):557-560
pubmed: 32340022
Anaesthesia. 2019 Mar;74(3):373-379
pubmed: 30648259
J Bone Joint Surg Am. 2017 Oct 18;99(20):e106
pubmed: 29040134
Lancet. 2020 Mar 28;395(10229):1033-1034
pubmed: 32192578
N Engl J Med. 2020 May 28;382(22):2163-2164
pubmed: 32283004
JAMA. 2020 May 12;323(18):1843-1844
pubmed: 32159775
BMJ. 2005 Dec 10;331(7529):1374
pubmed: 16299013
Korean J Radiol. 2020 Apr;21(4):494-500
pubmed: 32100485
Injury. 2020 Jun;51(6):1337-1342
pubmed: 32327234
J Clin Epidemiol. 1994 Nov;47(11):1245-51
pubmed: 7722560
J Bone Joint Surg Am. 2020 Jun 17;102(12):e58
pubmed: 32345864

Auteurs

Drake G LeBrun (DG)

Department of Orthopaedic Surgery, Hospital for Special Surgery, New York, NY.

Maxwell A Konnaris (MA)

HSS Research Institute, Hospital for Special Surgery, New York, NY.

Gregory C Ghahramani (GC)

HSS Research Institute, Hospital for Special Surgery, New York, NY.
Department of Physiology and Biophysics, Weill Cornell Medical College, New York, NY.

Ajay Premkumar (A)

Department of Orthopaedic Surgery, Hospital for Special Surgery, New York, NY.

Chris J DeFrancesco (CJ)

Department of Orthopaedic Surgery, Hospital for Special Surgery, New York, NY.

Jordan A Gruskay (JA)

Department of Orthopaedic Surgery, Hospital for Special Surgery, New York, NY.

Aleksey Dvorzhinskiy (A)

Department of Orthopaedic Surgery, Hospital for Special Surgery, New York, NY.

Milan S Sandhu (MS)

Weill Cornell Medical College, New York, NY.

Elan M Goldwyn (EM)

Department of Orthopaedic Surgery, Orthopaedic Trauma Service, NewYork Presbyterian Queens, Flushing, NY; and.

Christopher L Mendias (CL)

HSS Research Institute, Hospital for Special Surgery, New York, NY.
Department of Physiology and Biophysics, Weill Cornell Medical College, New York, NY.

William M Ricci (WM)

Department of Orthopaedic Surgery, Orthopaedic Trauma Service, Hospital for Special Surgery, New York, NY.

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