Phantom bursting may underlie electrical bursting in single pancreatic β-cells.

Calcium / metabolism Glucose / metabolism Insulin / metabolism Insulin Secretion Insulin-Secreting Cells / metabolism Islets of Langerhans / metabolism Models, Biological
Electrical activity Fast-slow analysis Glycolytic oscillations Islet Oscillations

Journal

Journal of theoretical biology
ISSN: 1095-8541
Titre abrégé: J Theor Biol
Pays: England
ID NLM: 0376342

Informations de publication

Date de publication:
21 09 2020
Historique:
received: 06 01 2020
revised: 18 05 2020
accepted: 23 05 2020
pubmed: 9 6 2020
medline: 22 6 2021
entrez: 8 6 2020
Statut: ppublish

Résumé

Insulin is secreted by pancreatic β-cellsthat are electrically coupled into micro-organs called islets of Langerhans. The secretion is due to the influx of Ca

Identifiants

DOI: 10.1016/j.jtbi.2020.110346 PMID: 32505826
pubmed: 32505826
pii: S0022-5193(20)30201-0
doi: 10.1016/j.jtbi.2020.110346
pii:
doi:

Substances chimiques

Insulin 0
Glucose IY9XDZ35W2
Calcium SY7Q814VUP

Types de publication

Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

110346

Informations de copyright

Copyright © 2020 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Mehran Fazli (M)

Florida State University, Department of Mathematics, Tallahassee, FL, United States.

Theodore Vo (T)

Monash University, School of Mathematics, Clayton, Victoria, Australia.

Richard Bertram (R)

Florida State University, Department of Mathematics and Programs in Neuroscience and Molecular Biophysics, Tallahassee, FL, United States.

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Classifications MeSH

questionsmedicales.fr › Facteurs biologiques › Facteurs de la coagulation sanguine › Calcium › Phantom bursting may underlie electrical...
questionsmedicales.fr › Glucides › Sucres › Oses › Hexose › Glucose › Phantom bursting may underlie electrical...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Hormones peptidiques › Hormones pancréatiques › Insulines › Insuline › Phantom bursting may underlie electrical...
questionsmedicales.fr › Phénomènes physiologiques › Sécrétion d'insuline › Phantom bursting may underlie electrical...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules entéroendocrines › Cellules à insuline › Phantom bursting may underlie electrical...
questionsmedicales.fr › Système endocrine › Glandes endocrines › Ilots pancréatiques › Phantom bursting may underlie electrical...
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles biologiques › Phantom bursting may underlie electrical...