Caffeic Acid Protects against Iron-Induced Cardiotoxicity by Suppressing Angiotensin-Converting Enzyme Activity and Modulating Lipid Spectrum, Gluconeogenesis and Nucleotide Hydrolyzing Enzyme Activities.


Journal

Biological trace element research
ISSN: 1559-0720
Titre abrégé: Biol Trace Elem Res
Pays: United States
ID NLM: 7911509

Informations de publication

Date de publication:
Mar 2021
Historique:
received: 31 03 2020
accepted: 28 05 2020
pubmed: 9 6 2020
medline: 22 6 2021
entrez: 8 6 2020
Statut: ppublish

Résumé

The protective effects of caffeic acid on angiotensin-converting enzyme (ACE) and purinergic enzyme activities, as well as gluconeogenesis was investigated in iron-induced cardiotoxicity. Cardiotoxicity was induced in heart tissues harvested from healthy male SD rats by 0.1 mM FeSO

Identifiants

pubmed: 32506180
doi: 10.1007/s12011-020-02227-3
pii: 10.1007/s12011-020-02227-3
doi:

Substances chimiques

Angiotensins 0
Antioxidants 0
Caffeic Acids 0
Lipids 0
Nucleotides 0
Iron E1UOL152H7
caffeic acid U2S3A33KVM

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1052-1061

Subventions

Organisme : Inyuvesi Yakwazulu-Natali
ID : 218087036
Organisme : National Department of Health (ZA)
ID : Grant Support for Women and Young Researchers

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Auteurs

Veronica F Salau (VF)

Department of Biochemistry, School of Life Sciences, University of KwaZulu-Natal, Westville Campus, Durban, 4000, South Africa.
Department of Biochemistry, Veritas University, Bwari, Abuja, Nigeria.

Ochuko L Erukainure (OL)

Department of Biochemistry, School of Life Sciences, University of KwaZulu-Natal, Westville Campus, Durban, 4000, South Africa.
Department of Pharmacology, University of the Free State, Bloemfontein, 9300, South Africa.

Md Shahidul Islam (MS)

Department of Biochemistry, School of Life Sciences, University of KwaZulu-Natal, Westville Campus, Durban, 4000, South Africa. islamd@ukzn.ac.za.

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Classifications MeSH