Dysautonomia secondary to third ventriculostomy successfully managed with midodrine.
drugs: CNS (not psychiatric)
neuroendocrinology
neurological injury
neurology (drugs and medicines)
neurosurgery
Journal
BMJ case reports
ISSN: 1757-790X
Titre abrégé: BMJ Case Rep
Pays: England
ID NLM: 101526291
Informations de publication
Date de publication:
17 Jun 2020
17 Jun 2020
Historique:
entrez:
20
6
2020
pubmed:
20
6
2020
medline:
10
2
2021
Statut:
epublish
Résumé
Hypothalamic lesions can compromise its essential regulatory roles resulting in critical disruption of temperature and blood pressure homoeostasis. We present the case of a 55-year-old woman who had been previously submitted to several neurosurgical procedures aimed at treating idiopathic hydrocephalus. She presented to our department with recurring episodes of hypothermia and wide blood pressure variations, which had been worsening over the last few years. After extensive complementary workup, which excluded new neurological lesions or endocrinological conditions, hypothalamic dysfunction was assumed to be the cause of this syndrome. She was successfully treated with midodrine and on-demand captopril, which resulted in adequate control of her blood pressure. This case highlights the rare and unpredictable consequences of damage to the hypothalamus, depicting the favourable result of a heretofore unpublished medical approach.
Identifiants
pubmed: 32554459
pii: 13/6/e232767
doi: 10.1136/bcr-2019-232767
pmc: PMC7304637
pii:
doi:
Substances chimiques
Midodrine
6YE7PBM15H
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
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