Genomic characterization of pestiviruses isolated from bovine, ovine and caprine foetuses in Turkey: A potentially new genotype of Pestivirus I species.
5' Untranslated Regions
Abortion, Veterinary
/ virology
Animals
Cattle
Cattle Diseases
/ virology
Fetal Diseases
/ veterinary
Fetus
/ virology
Genome, Viral
Genomics
Genotype
Goat Diseases
/ virology
Goats
Pestivirus
/ classification
Pestivirus Infections
/ veterinary
Phylogeny
Sheep
Sheep Diseases
/ virology
Turkey
abortion
cattle
genetic characterization
goats
pestivirus
sheep
Journal
Transboundary and emerging diseases
ISSN: 1865-1682
Titre abrégé: Transbound Emerg Dis
Pays: Germany
ID NLM: 101319538
Informations de publication
Date de publication:
Mar 2021
Mar 2021
Historique:
revised:
10
06
2020
received:
24
02
2020
accepted:
11
06
2020
pubmed:
22
6
2020
medline:
8
6
2021
entrez:
22
6
2020
Statut:
ppublish
Résumé
This study was carried out to investigate the frequency and genetic diversity of pestiviruses in abortion cases in cattle and small ruminants in Turkey. During January 2012 and December 2017, a total of 2029 aborted foetuses (553 bovine foetuses, 1,388 sheep foetuses and 88 goat foetuses) were collected from different regions of Turkey. Real-time RT-PCR (RRT-PCR) assays were used to detect pestiviral RNA in aborted foetuses. To confirm the cause of abortion, pestivirus-positive foetuses were also examined for the presence of Brucella spp., Campylobacter spp., Chlamydophila abortus (C. abortus), akabane virus, bluetongue virus and Schmallenberg virus by molecular detection methods. Pestiviral RNA was detected in 61 (11%) of the 553 bovine foetuses, 124 (8.9%) of the 1,388 sheep foetuses and 3 (3.4%) of the 88 goat foetuses. Furthermore, C. abortus DNA was detected in 3 pestivirus-positive sheep foetuses, whereas other infectious agents were not detected in pestivirus-positive foetuses. Genetic characterization of the pestivirus RRT-PCR positive samples was conducted by sequencing 5' untranslated (5' UTR) and non-structural autoprotease (N
Substances chimiques
5' Untranslated Regions
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
417-426Informations de copyright
© 2020 Blackwell Verlag GmbH.
Références
Aras, Z., Sayin, Z., & Golen, G. S. (2017). Investigation of Chlamydophila abortus in abortion of cattle by PCR. Eurasian Journal of Veterinary Sciences, 33(2), 77-80. https://doi.org/10.15312/EurasianJVetSci.2017.140
Aslan, S., Yoldas, A., Yigin, A., Demirci, M., & Saglam, F. Y. (2016). Quantitative analysis of brucella spp in aborted bovine fetuses by real-time PCR. 17th International Congress on Infectious Diseases /. International Journal of Infectious Diseases, 45(1), 477. https://doi.org/10.1016/j.ijid.2016.02.1006
Becher, P., Meyers, G., Shannon, A. D., & Thiel, H. J. (1996). Cytopathogenicity of border disease virus is correlated with integration of cellular sequences into the viral genome. Journal of Virology, 70(5), 2992-2998. https://doi.org/10.1128/JVI.70.5.2992-2998.1996
Becher, P., Shannon, A. D., Tautz, N., & Thiel, H. J. (1994). Molecular characterization of border disease virus, a pestivirus from sheep. Virology, 198, 542-551. https://doi.org/10.1006/viro.1994.1065
Bilk, S., Schulze, C., Fischer, M., Beer, M., Hlinak, A., & Hoffmann, B. (2012). Organ distribution of Schmallenberg virus RNA in malformed newborns. Veterinary Microbiology, 159(1-2), 236-238. https://doi.org/10.1016/j.vetmic.2012.03.035
Borel, N., Frey, C. F., Gottstein, B., Hilbe, M., Pospischil, A., Franzoso, F. D., & Waldvogel, A. (2014). Laboratory diagnosis of ruminant abortion in Europe. The Veterinary Journal, 200(2), 218-229. https://doi.org/10.1016/j.tvjl.2014.03.015
Braun, U., Reichle, S. F., Reichert, C., Hässig, M., Stalder, H. P., Bachofen, C., & Peterhans, E. (2014). Sheep persistently infected with Border disease readily transmit virus to calves seronegative to BVD virus. Veterinary Microbiology, 168(1), 98-104. https://doi.org/10.1016/j.vetmic.2013.11.004
Bricker, B. J., & Halling, S. M. (1994). Differentiation of Brucella abortus bv. 1, 2, and 4, Brucella melitensis, Brucella ovis, and Brucella suis bv. 1 by PCR. Journal of Clinical Microbiology, 32(11), 2660-2666.
Bulut, H., Sozdutmaz, I., Pestil, Z., Abayli, H., Sait, A., & Cevik, A. (2018). High prevalence of bovine viral diarrhea virus-1 in sheep abortion samples with pestivirus infection in Turkey. Pakistan Veterinary Journal, 38(1), 71-75. https://doi.org/10.29261/pakvetj/2018.014
Buyuk, F., & Sahin, M. (2011). Investigation of Brucella Species from Various Samples of Aborted Cattle in Kars Province (Turkey) by Cultural and Molecular Methods and Epidemiological Analysis of Cases. Kafkas Universitesi Veteriner Fakultesi Dergisi, 17(5), 809-816. https://doi.org/10.9775/kvfd.2011.4509
Carman, S., van Dreumel, T., Ridpath, J., Hazlett, M., Alves, D., Dubovi, E. D., … Anderson, N. (1998). Severe acute bovine viral diarrhea in Ontario, 1993-1995. Journal of Veterinary Diagnostic Investigation, 10(1), 27-35. https://doi.org/10.1177/104063879801000106
Cowley, D. J., Clegg, T. A., Doherty, M. L., & More, S. J. (2012). Bovine viral diarrhoea virus seroprevalence and vaccination usage in dairy and beef herds in the Republic of Ireland. Irish Veterinary Journal, 65(1), 16. https://doi.org/10.1186/2046-0481-65-16
Decaro, N., Lucente, M. S., Mari, V., Sciarretta, R., Pinto, P., Buonavoglia, D., … Buonavoglia, C. (2012). Hobi-like pestivirus in aborted bovine fetuses. Journal of Clinical Microbiology, 50(2), 509-512. https://doi.org/10.1128/JCM.05887-11
Decaro, N., Mari, V., Pinto, P., Lucente, M. S., Sciarretta, R., Cirone, F., … Buonavoglia, C. (2012). Hobi-like pestivirus: Both biotypes isolated from a diseased animal. The Journal of General Virology, 93(9), 1976-1983. https://doi.org/10.1099/vir.0.044552-0
Deng, M., Ji, S., Fei, W., Raza, S., He, C., Chen, Y., … Guo, A. (2015). Prevalence study and genetic typing of bovine viral diarrhea virus (BVDV) in four bovine species in China. PLoS One, 10(4), e0121718. https://doi.org/10.1371/journal.pone.0121718
Desport, M., & Brownlie, J. (1991). Molecular characterisation of the coding region for the p125 from homologous BVDV biotypes. Archives of Virology. Supplementum, 3, 261-265. https://doi.org/10.1007/978-3-7091-9153-8_33
Dewulf, J., Laevens, H., Koenen, F., Mintiens, K., & De Kruif, A. (2001). An experimental infection with classical swine fever virus in pregnant sows: Transmission of the virus, course of the disease, antibody response and effect on gestation. Journal of veterinary medicine. B, Infectious diseases and veterinary public. Health, 48(8), 583-591. https://doi.org/10.1046/j.1439-0450.2001.00467.x
Erganis, O., Kaya, O., Hadimli, H. H., & Guler, L. (2002). Rapid diagnosis of ovine Brucella, Campylobacter and Salmonella infections from fetal stomach contents by coagglutination test. Small Ruminant Research, 45(2), 123-127. https://doi.org/10.1016/S0921-4488(02)00091-3
García-Pérez, A. L., Minguijón, E., Barandika, J. F., Aduriz, G., Povedano, I., Juste, R. A., & Hurtado, A. (2009). Detection of Border disease virus in fetuses, stillbirths, and newborn lambs from natural and experimental infections. Journal of Veterinary Diagnostic Investigation, 21(3), 331-337. https://doi.org/10.1177/104063870902100304
Gil, L. H. V. G., Ansari, I. H., Vassilev, V., Liang, D., Lai, V. C. H., Zhong, W., … Donis, R. O. (2006). The amino-terminal domain of bovine viral diarrhea virus Npro protein is necessary for alpha/beta interferon antagonism. Journal of Virology, 80(2), 900-911. https://doi.org/10.1128/JVI.80.2.900-911.2006
Gillespie, J. H., Barholomew, P. T., Thompson, R. G., & McEntee, K. (1967). The isolation of noncytopathic virus diarrhea virus from two aborted fetuses. Cornell Veterinarian, 57, 564-571.
Gómez-Romero, N., Basurto-Alcántara, F. J., Verdugo-Rodríguez, A., Lagunes-Quintanilla, R., Bauermann, F. V., & Ridpath, J. F. (2018). Detection of border disease virus in Mexican cattle. Transboundary and Emerging Diseases, 65(1), 267-271. https://doi.org/10.1111/tbed.12641
Greiser-Wilke, I., Haas, L., Dittmar, K., Liess, B., & Moennig, V. (1993). RNA insertions and gene duplications in the nonstructural protein p125 region of pestivirus strains and isolates in vitro and in vivo. Virology, 193(2), 977-980. https://doi.org/10.1006/viro.1993.1209
Grooms, D. L. (2004). Reproductive consequences of infection with bovine viral diarrhea virus. The Veterinary Clinics of North America. Food Animal Practice, 20(1), 5-19. https://doi.org/10.1016/j.cvfa.2003.11.006
Guler, L., Hadimli, H. H., Erganiş, O., Ateş, M., Ok, U., & Gunduz, K. (2006). Field evaluation of a PCR for the diagnosis of chlamydial abortion in sheep. The Veterinary Record, 159, 742-745. https://doi.org/10.1136/vr.159.22.742
Gur, S. (2008). A serologic investigation of blue tongue virus (BTV) in cattle, sheep and gazella subgutturosa subgutturosa in southeastern Turkey. Tropical Animal Health and Production, 40(3), 217-221. https://doi.org/10.1007/s11250-007-9083-4
Haligur, M., Hasircioglu, S., Ozmen, O., Kale, M., & Aydogan, A. (2014). Immunohistochemical evaluation of akabane virus infection in aborted and new-born calves. Veterinarni Medicina, 59(5), 230-238. https://doi.org/10.17221/7516-VETMED
Harasawa, R., & Giangaspero, M. (1998). A novel method for pestivirus genotyping based on palindromic nucleotide substitutions in the 5'-untranslated region. Journal of Virological Methods, 70(2), 225-230. https://doi.org/10.1016/s0166-0934(97)00180-8
Hofmann, M., Griot, C., Chaignat, V., Perler, L., & Thür, B. (2008). Bluetongue disease reaches Switzerland. Schweizer Archiv Für Tierheilkunde, 150(2), 49-56. https://doi.org/10.1024/0036-7281.150.2.49
Ica, T., Aydin, F., Gumussoy, K. S., Percin, D., Sumerkan, A. B., Ocak, F.,& Ciftci, A. (2012). Conventional and molecular biotyping of Brucella strains isolated from cattle, sheep and human. Ankara Universitesi Veteriner Fakultesi Dergisi, 59, 259-264.
Kadir, Y., Christine, F., Barbara, B.-W., Zeki, Y., Feray, A., Aykut, O., … Matthias, K. (2008). Genetic heterogeneity of bovine viral diarrhoea virus BVDV isolates from Turkey, Identification of a new subgroup in BVDV-1. Veterinary Microbiology, 130(3-4), 258-267. https://doi.org/10.1016/j.vetmic.2008.01.016
Kalender, H., Kilic, A., Eroksuz, H., Muz, A., Kilinc, U., & Tasdemir, B. (2013). Identification of Chlamydophila abortus infection in aborting ewes and goats in Eastern Turkey. Revuede Medecine Veterinaire, 164, 295-301.
Kawanishi, N., Tsuduku, S., Shimizu, H., Ohtani, Y., Kameyama, K.-I., Yamakawa, M., … Yamada, S. (2014). First isolation of border disease virus in Japan is from a pig farm with no ruminants. Veterinary Microbiology, 171(1-2), 210-214. https://doi.org/10.1016/j.vetmic.2014.03.032
Kilic, A., Kalender, H., & Muz, A. (2010). The Detection of Chlamydophila abortus from Aborted Bovine Fetuses Using PCR and Microbiological Culture. Firat University Veterinary Journal of Health Sciences, 24(3), 129-132.
Krametter-Froetscher, R., Duenser, M., Preyler, B., Theiner, A., Benetka, V., Moestl, K., & Baumgartner, W. (2010). Pestivirus infection in sheep and goats in West Austria. The Veterinary Journal, 186(3), 342-346. https://doi.org/10.1016/j.tvjl.2009.09.006
Kucukayan, U., Dakman, A., Ulker, U., & Mustak, K. (2007). Investigation of sheep sera and foetuses for the identification of abortifacient bacterial agents. Journal of Etlik Veterinary Microbiology, 18, 11-16.
La Rocca, S. A., & Sandvik, T. (2009). A short target real-time RT-PCR assay for detection of pestiviruses infecting cattle. Journal of Virological Methods, 161(1), 122-127. https://doi.org/10.1016/j.jviromet.2009.06.005
Liu, L., Xia, H., Wahlberg, N., Belák, S., & Baule, C. (2009). Phylogeny, classification and evolutionary insights into pestiviruses. Virology, 385(2), 351-357. https://doi.org/10.1016/j.virol.2008.12.004
Logan, J. M., Edwards, K. J., Saunders, N. A., & Stanley, J. (2001). Rapid identification of Campylobacter spp. by melting peak analysis of biprobes in real-time PCR. Journal of Clinical Microbiology, 39(6), 2227-2232. https://doi.org/10.1128/JCM.39.6.2227-2232.2001
Løken, T., & Bjerkas, I. (1991). Experimental pestivirus infections in pregnant goats. Journal of Comparative Pathology, 105(2), 123-140. https://doi.org/10.1016/S0021-9975(08)80068-0
MacLachlan, N. J., & Dubovi, E. J. (2011). Flaviviridae. In N. J. MacLachlan, & E. J. Dubovi (Eds.), Fenner’s Veterinary Virology, (4th ed.; pp. 467-481). London, UK: Academic Press.
Mari, V., Losurdo, M., Lucente, M. S., Lorusso, E., Elia, G., Martella, V., … Decaro, N. (2016). Multiplex real-time RT-PCR assay for bovine viral diarrhea virus type 1, type 2 and HoBi-like pestivirus. Journal of Virological Methods, 229, 1-7. https://doi.org/10.1016/j.jviromet.2015.12.003
Nettleton, P. F., Gilray, J. A., Russo, P., & Dlissi, E. (1998). Border disease of sheep and goats. Veterinary Research, 29(3-4), 327-340.
Oguzoglu, T. C., Koc, B. T., Coskun, N., Dogan, F., & Duran-Yelken, S. (2019). Endless variety for bovine virus diarrhea viruses: New members of a novel subgroup into Pestivirus A from Turkey. Tropical Animal Health and Production, 51(5), 1083-1087. https://doi.org/10.1007/s11250-018-01787-w
Oguzoglu, T. C., Muz, D., Yilmaz, V., Timurkan, M. O., Alkan, F., Akca, Y., & Burgu, I. (2012). Molecular characteristics of bovine virus diarrhoea virus 1 isolates from Turkey: Approaches for an eradication programme. Transboundary and Emerging Diseases, 59(4), 303-310. https://doi.org/10.1111/j.1865-1682.2011.01272.x
Oguzoglu, T. C., Tan, M. T., Toplu, N., Demir, A. B., Bilge-Dagalp, S., Karaoglu, T., … Greiser-Wilke, I. (2009). Border disease virus (BDV) infections of small ruminants in Turkey: A new BDV subgroup? Veterinary Microbiology, 135(3-4), 374-379. https://doi.org/10.1016/j.vetmic.2008.09.085
OIE (2018). Border Disease. Manual of Diagnostic Tests and Vaccines for Terrestrial Animals 2019 (pp. 1407-1419). Retrieved from https://www.oie.int/fileadmin/Home/eng/Health_standards/tahm/3.07.01_BORDER_DIS.pdf
Pantchev, A., Sting, R., Bauerfeind, R., Tyczka, J., & Sachse, K. (2010). Detection of all Chlamydophila and Chlamydia spp. of veterinary interest using species-specific real-time PCR assays. Comparative Immunology, Microbiology and Infectious Diseases, 33(6), 473-484. https://doi.org/10.1016/j.cimid.2009.08.002
Ridpath, J. F., Fulton, R. W., Kirkland, P. D., & Neill, J. D. (2010). Prevalence and antigenic differences observed between Bovine viral diarrhea virus subgenotypes isolated from cattle in Australia and feedlots in the southwestern United States. Journal of Veterinary Diagnostic Investigation, 22(2), 184-191. https://doi.org/10.1177/104063871002200203
Ruggli, N., Bird, B. H., Liu, L., Bauhofer, O., Tratschin, J. D., & Hofmann, M. A. (2005). N(pro) of classical swine fever virus is an antagonist of double-stranded RNA-mediated apoptosis and IFN-alpha/beta induction. Virology, 340(2), 265-276. https://doi.org/10.1016/j.virol.2005.06.033
Saglam, Y. S., Turkutanit, S. S., Tastan, R., Bozoglu, H., & Otlu, S. (1998). Etiological and pathological studies on bacterial abortions of sheeps and cattles in North-East Anatolia Region. Selcuk Universitesi Veteriner Bilimler Dergisi, 14(2), 133-145.
Scott, F. W., Kahrs, R. F., & Parsonson, I. M. (1972). A cytopathogenic strain of bovine viral diarrhea-mucosal disease virus isolated from a bovine fetus. Cornell Veterinarian, 62, 74-84.
Serrano, E., Colom-Cadena, A., Gilot-Fromont, E., Garel, M., Cabezón, O., Velarde, R., … Marco, I. (2015). Border disease virus: An exceptional driver of chamois populations among other threats. Frontiers in Microbiology, 6, 1307. https://doi.org/10.3389/fmicb.2015.01307
Sevik, M. (2017). Molecular and serological survey of Akabane virus infection in sheep in the Mediterranean Region of Turkey. Small Ruminant Research, 156, 1-6. https://doi.org/10.1016/j.smallrumres.2017.07.012
Smith, D. B., Meyers, G., Bukh, J., Gould, E. A., Monath, T., Scott Muerhoff, A., … Becher, P. (2017). Proposed revision to the taxonomy of the genus Pestivirus, family Flaviviridae. The Journal of General Virology, 98(8), 2106-2112. https://doi.org/10.1099/jgv.0.000873
Stram, Y., Kuznetzova, L., Guini, M., Rogel, A., Meirom, R., Chai, D., … Brenner, J. (2004). Detection and quantitation of akabane and aino viruses by multiplex real-time reverse-transcriptase PCR. Journal of Virological Methods, 116(2), 147-154. https://doi.org/10.1016/j.jviromet.2003.11.010
Sullivan, D. G., Chang, G. J., & Akkina, R. K. (1997). Genetic characterization of ruminant pestiviruses: Sequence analysis of viral genotypes isolated from sheep. Virus Research, 47, 19-29. https://doi.org/10.1016/S0168-1702(96)01402-5
Tamura, K., Stecher, G., Peterson, D., Filipski, A., & Kumar, S. (2013). MEGA6: Molecular evolutionary genetics analysis version 6.0. Molecular Biology and Evolution, 30(12), 2725-2729. https://doi.org/10.1093/molbev/mst197
Timurkan, M. O., & Aydın, H. (2019). Increased genetic diversity of BVDV strains circulating in Eastern Anatolia, Turkey: First detection of BVDV-3 in Turkey. Tropical Animal Health and Production, 51(7), 1953-1961. https://doi.org/10.1007/s11250-019-01901-6
Topliff, C. L., & Kelling, C. L. (1998). Virulence markers in the 5' untranslated region of genotype 2 bovine viral diarrhea virus isolates. Virology, 250(1), 164-172. https://doi.org/10.1006/viro.1998.9350
Toplu, N., Oguzoglu, T. C., & Albayrak, H. (2012). Dual infection of fetal and neonatal small ruminants with border disease virus and peste des petits ruminants virus (PPRV): Neuronal tropism of PPRV as a novel finding. Journal of Comparative Pathology, 146(4), 289-297. https://doi.org/10.1016/j.jcpa.2011.07.004
Tuncer-Goktuna, P., Alpay, G., Oner, E. B., & Yesilbag, K. (2017). Co-existence of bovine viral diarrhea and border disease viruses in a sheep flock suffering from abortus and diarrhea. Turkish Journal of Veterinary and Animal Sciences, 41(5), 590-597. https://doi.org/10.3906/vet-1701-3
Turkish Statistical Institute (2017). Animal production statistics, 2017. Retrieved from https://biruni.tuik.gov.tr/ilgosterge/?locale=tr
Tuzcu, M., Oruc, E., Tuzcu, N., Yoldas, A., & Yigin, A. (2010). Diagnosis of campylobacteriosis in the aborted bovine foetuses by pathological, immunohistochemical, microbiological and real time PCR. Kafkas Universitesi Veteriner Fakultesi Dergisi, 16(3), 509-514.
Vilcek, S., Herring, A. J., Herring, J. A., Nettleton, P. F., Lowings, J. P., & Paton, D. J. (1994). Pestiviruses isolated from pigs, cattle and sheep can be allocated into at least three genogroups using polymerase chain reaction and restriction endonuclease analysis. Archives of Virology, 136(3-4), 309-323. https://doi.org/10.1007/BF01321060
Vilcek, S., Nettleton, P. F., Paton, D. J., & Belák, S. (1997). Molecular characterization of ovine pestiviruses. The Journal of General Virology, 78(4), 725-735. https://doi.org/10.1099/0022-1317-78-4-725
Vilček, Š., Paton, D. J., Durkovic, B., Strojny, L., Ibata, G., Moussa, A., … Palfi, V. (2001). Bovine viral diarrhoea virus genotype 1 can be separated into at least eleven genetic groups. Archives of Virology, 146(1), 99-115. https://doi.org/10.1007/s007050170194
Yesilbag, K., Alpay, G., & Becher, P. (2017). Variability and global distribution of subgenotypes of bovine viral diarrhea virus. Viruses, 9(6), E128. https://doi.org/10.3390/v9060128
Yilmaz, H., Hoffmann, B., Turan, N., Cizmecigil, U. Y., Richt, J. A., & Van der Poel, W. H. (2014). Detection and partial sequencing of Schmallenberg virus in cattle and sheep in Turkey. Vector Borne and Zoonotic Diseases, 14(3), 223-225. https://doi.org/10.1089/vbz.2013.1451