A Clerodane Diterpene from


Journal

ACS infectious diseases
ISSN: 2373-8227
Titre abrégé: ACS Infect Dis
Pays: United States
ID NLM: 101654580

Informations de publication

Date de publication:
10 07 2020
Historique:
pubmed: 25 6 2020
medline: 24 6 2021
entrez: 25 6 2020
Statut: ppublish

Résumé

The rise of antibiotic resistance presents a significant healthcare challenge and precludes the use of many otherwise valuable antibiotics. One potential solution to this problem is the use of antibiotics in combination with resistance-modifying agents, compounds that act synergistically with existing antibiotics to resensitize previously resistant bacteria. In this study, 12(

Identifiants

pubmed: 32579326
doi: 10.1021/acsinfecdis.0c00307
pmc: PMC8183163
mid: NIHMS1709139
doi:

Substances chimiques

Anti-Bacterial Agents 0
Diterpenes, Clerodane 0
Oxacillin UH95VD7V76

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

1667-1673

Subventions

Organisme : NIDCR NIH HHS
ID : R01 DE022350
Pays : United States
Organisme : NIAID NIH HHS
ID : R21 AI136563
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM008602
Pays : United States

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Auteurs

Micah Dettweiler (M)

Emory University, Department of Dermatology, 615 Michael Street, Whitehead 105L, Atlanta, Georgia 30322, United States.

Roberta J Melander (RJ)

Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.

Gina Porras (G)

Emory University, Center for the Study of Human Health, 1557 Dickey Drive, Anthropology 306, Atlanta, Georgia 30322, United States.

Caitlin Risener (C)

Emory University, Molecular and Systems Pharmacology Program, 615 Michael Street, Whitehead 115, Atlanta, Georgia 30322, United States.

Lewis Marquez (L)

Emory University, Molecular and Systems Pharmacology Program, 615 Michael Street, Whitehead 115, Atlanta, Georgia 30322, United States.

Tharanga Samarakoon (T)

Emory University Herbarium, 1462 Clifton Road, Atlanta, Georgia 30322, United States.

Christian Melander (C)

Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.

Cassandra L Quave (CL)

Emory University, Department of Dermatology, 615 Michael Street, Whitehead 105L, Atlanta, Georgia 30322, United States.
Emory University, Center for the Study of Human Health, 1557 Dickey Drive, Anthropology 306, Atlanta, Georgia 30322, United States.
Emory University, Molecular and Systems Pharmacology Program, 615 Michael Street, Whitehead 115, Atlanta, Georgia 30322, United States.

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Classifications MeSH