Vector competence of Aedes albopictus populations for chikungunya virus is shaped by their demographic history.


Journal

Communications biology
ISSN: 2399-3642
Titre abrégé: Commun Biol
Pays: England
ID NLM: 101719179

Informations de publication

Date de publication:
24 06 2020
Historique:
received: 14 01 2020
accepted: 26 05 2020
entrez: 26 6 2020
pubmed: 26 6 2020
medline: 24 6 2021
Statut: epublish

Résumé

The mosquito Aedes albopictus is one of the most dangerous invasive species. Its worldwide spread has created health concerns as it is a major vector of arboviruses of public health significance such as chikungunya (CHIKV). Dynamics of different genetic backgrounds and admixture events may have impacted competence for CHIKV in adventive populations. Using microsatellites, we infer the genetic structure of populations across the expansion areas that we then associate with their competence for different CHIKV genotypes. Here we show that the demographic history of Ae. albopictus populations is a consequence of rapid complex patterns of historical lineage diversification and divergence that influenced their competence for CHIKV. The history of adventive populations is associated with CHIKV genotypes in a genotype-by-genotype interaction that impacts their vector competence. Thus, knowledge of the demographic history and vector competence of invasive mosquitoes is pivotal for assessing the risk of arbovirus outbreaks in newly colonized areas.

Identifiants

pubmed: 32581265
doi: 10.1038/s42003-020-1046-6
pii: 10.1038/s42003-020-1046-6
pmc: PMC7314749
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

326

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Auteurs

Anubis Vega-Rúa (A)

Laboratory of Vector Control Research, Institut Pasteur of Guadeloupe, 97139, Guadeloupe, France.

Michele Marconcini (M)

Department of Biology and Biotechnology, University of Pavia, Via Ferrata 9, 27100, Pavia, Italy.

Yoann Madec (Y)

Department of Infection and Epidemiology of Emerging Diseases, Institut Pasteur, 25-28 rue du Dr Roux, 75724, Paris, France.

Mosè Manni (M)

Department of Biology and Biotechnology, University of Pavia, Via Ferrata 9, 27100, Pavia, Italy.
Department of Genetic Medicine and Development, University of Geneva Medical School, 1 rue Michel-Servet 1211 Genève and Swiss Institute of Bioinformatics, Geneva, Switzerland.

Davide Carraretto (D)

Department of Biology and Biotechnology, University of Pavia, Via Ferrata 9, 27100, Pavia, Italy.

Ludvik Marcus Gomulski (LM)

Department of Biology and Biotechnology, University of Pavia, Via Ferrata 9, 27100, Pavia, Italy.

Giuliano Gasperi (G)

Department of Biology and Biotechnology, University of Pavia, Via Ferrata 9, 27100, Pavia, Italy. gasperi@unipv.it.

Anna-Bella Failloux (AB)

Department of Virology, Arboviruses and Insect Vectors Unit, Institut Pasteur, 25-28 rue du Dr Roux, 75724, Paris, France. anna-bella.failloux@pasteur.fr.

Anna Rodolfa Malacrida (AR)

Department of Biology and Biotechnology, University of Pavia, Via Ferrata 9, 27100, Pavia, Italy. malacrid@unipv.it.

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