A case of congenital toxoplasmosis-associated miscarriage with maternal infection four months prior to conception.
Congenital toxoplasmosis
Fetal death
Miscarriage
Preconception
Toxoplasma gondii
Journal
Parasitology international
ISSN: 1873-0329
Titre abrégé: Parasitol Int
Pays: Netherlands
ID NLM: 9708549
Informations de publication
Date de publication:
Dec 2020
Dec 2020
Historique:
received:
17
04
2020
revised:
18
06
2020
accepted:
20
06
2020
pubmed:
27
6
2020
medline:
17
4
2021
entrez:
27
6
2020
Statut:
ppublish
Résumé
We report a case of fatal congenital toxoplasmosis with maternal infection dated four months before pregnancy in the absence of any specific immunosuppressive condition. Ms. D. experienced submaxillary lymphadenitis in February 2018. The medical workup performed revealed an acute T. gondii infection. She became pregnant in June 2018 while she still had adenopathy. The second obstetrical ultrasound, performed at 16 weeks of pregnancy, revealed a fetal death. The research for T. gondii by PCR was positive in the products of conception. Diagnosis of toxoplasmosis should be discussed in case of miscarriage with lymphadenitis. As lymph nodes in T. gondii infection could be responsible for iterative release of parasites and fetal death, symptomatic toxoplasmosis should be treated in women of childbearing age.
Sections du résumé
BACKGROUND
BACKGROUND
We report a case of fatal congenital toxoplasmosis with maternal infection dated four months before pregnancy in the absence of any specific immunosuppressive condition.
CASE
METHODS
Ms. D. experienced submaxillary lymphadenitis in February 2018. The medical workup performed revealed an acute T. gondii infection. She became pregnant in June 2018 while she still had adenopathy. The second obstetrical ultrasound, performed at 16 weeks of pregnancy, revealed a fetal death. The research for T. gondii by PCR was positive in the products of conception.
CONCLUSION
CONCLUSIONS
Diagnosis of toxoplasmosis should be discussed in case of miscarriage with lymphadenitis. As lymph nodes in T. gondii infection could be responsible for iterative release of parasites and fetal death, symptomatic toxoplasmosis should be treated in women of childbearing age.
Identifiants
pubmed: 32589941
pii: S1383-5769(20)30115-X
doi: 10.1016/j.parint.2020.102165
pii:
doi:
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
102165Informations de copyright
Copyright © 2020 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors have no competing interests and no financial support or funding to declare.