Association of guideline publication and delays to treatment in pediatric status epilepticus.
Adolescent
Anticonvulsants
/ therapeutic use
Benzodiazepines
/ therapeutic use
Cerebral Palsy
/ epidemiology
Child
Child, Preschool
Developmental Disabilities
/ epidemiology
Emergency Medical Services
/ statistics & numerical data
Epilepsy
/ epidemiology
Evidence-Based Medicine
Female
Hospital Mortality
Hospitals, Pediatric
Humans
Infant
Infusions, Intravenous
Intellectual Disability
/ epidemiology
Intensive Care Units, Pediatric
Length of Stay
Male
Practice Guidelines as Topic
Professional Practice Gaps
/ statistics & numerical data
Retrospective Studies
Status Epilepticus
/ drug therapy
Time-to-Treatment
/ statistics & numerical data
Young Adult
Journal
Neurology
ISSN: 1526-632X
Titre abrégé: Neurology
Pays: United States
ID NLM: 0401060
Informations de publication
Date de publication:
01 09 2020
01 09 2020
Historique:
received:
24
10
2019
accepted:
04
03
2020
pubmed:
3
7
2020
medline:
27
10
2020
entrez:
3
7
2020
Statut:
ppublish
Résumé
To determine whether publication of evidence on delays in time to treatment shortens time to treatment in pediatric refractory convulsive status epilepticus (rSE), we compared time to treatment before (2011-2014) and after (2015-2019) publication of evidence of delays in treatment of rSE in the Pediatric Status Epilepticus Research Group (pSERG) as assessed by patient interviews and record review. We performed a retrospective analysis of a prospectively collected dataset from June 2011 to September 2019 on pediatric patients (1 month-21 years of age) with rSE. We studied 328 patients (56% male) with median (25th-75th percentile [p Publication of evidence on delays in time to treatment was not associated with improvements in time to treatment of rSE, although it was associated with an increase in the proportion of patients who received at least 1 BZD before hospital arrival.
Identifiants
pubmed: 32611646
pii: WNL.0000000000010174
doi: 10.1212/WNL.0000000000010174
pmc: PMC7538224
doi:
Substances chimiques
Anticonvulsants
0
Benzodiazepines
12794-10-4
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e1222-e1235Investigateurs
Seema Bansal
(S)
Sarah Kelley
(S)
Carl Stafstrom
(C)
Eric Kossoff
(E)
Christa Habela
(C)
Dalila Lewis
(D)
Tony Stanfield
(T)
Claudine Sculier
(C)
Arnold Sansevere
(A)
Kush Kapur
(K)
Melissa Sacco
(M)
Abby Duncan
(A)
Jordan McCoy
(J)
Kathryn DaSilva-Chiodo
(K)
Robert Faist
(R)
Daniel Santel
(D)
Victor LaFay
(V)
Peggy Clark
(P)
Sarah Borror
(S)
Andrea Debs
(A)
Caitlin Clohessy
(C)
Amanda Weber
(A)
Asri Yuliati
(A)
Aimee Luat
(A)
Azara Singh
(A)
Ashley Helseth
(A)
David Turner
(D)
Cecilia Fernandes
(C)
Linh Tran
(L)
Melissa McLean
(M)
Anuranjita Nayak
(A)
James J. Riviello
(JJ)
Kurt Hecox
(K)
Rupa Nallamothu
(R)
Rebecca Rehborg
(R)
David Goldstein
(D)
Erin Heinzen Cox
(EH)
Colin Malone
(C)
Olivia Thornburg
(O)
Zachary Grinspan
(Z)
Natasha Basma
(N)
Brian Appavu
(B)
Brian Burrows
(B)
Beata Dyar
(B)
Laura Mishler
(L)
Jacqueline Lee-Eng
(J)
Madison Streb
(M)
Cecil Hahn
(C)
Saptharishi (Rishi) Lalgudi Ganesan
(SL)
Linda Huh
(L)
Nela Martic
(N)
Jantzen Fan
(J)
Osama Al-Jawadi
(O)
Conrado DeGuzman
(C)
Meghan Boersma
(M)
Steven Wainstein
(S)
Nathan Dean
(N)
Adrian Bumbut
(A)
Katherine Sperberg
(K)
Renee Shellhaas
(R)
Guilia Benedetti
(G)
Garnett Smith
(G)
Stephanie Rau
(S)
Shannon Lester-Pelham
(S)
Olga Selioutski
(O)
Inna Hughes
(I)
Lurie Seltzer
(L)
Commentaires et corrections
Type : CommentIn
Type : CommentIn
Informations de copyright
Copyright © 2020 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology.
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