Systemic Capillary Leak Syndrome Secondary to Coronavirus Disease 2019.
Abdominal Pain
/ etiology
Acidosis, Lactic
/ etiology
Acute Kidney Injury
/ etiology
COVID-19
/ complications
Capillary Leak Syndrome
/ etiology
Compartment Syndromes
/ etiology
Continuous Renal Replacement Therapy
Crystalloid Solutions
/ therapeutic use
Edema
/ etiology
Fasciotomy
Fatal Outcome
Fluid Therapy
Hematocrit
Humans
Hypoalbuminemia
/ etiology
Male
Middle Aged
Respiration, Artificial
Rhabdomyolysis
/ etiology
Shock
/ etiology
Tomography, X-Ray Computed
Vasoconstrictor Agents
/ therapeutic use
COVID-19
capillary leak
shock
systemic capillary leak syndrome
Journal
Chest
ISSN: 1931-3543
Titre abrégé: Chest
Pays: United States
ID NLM: 0231335
Informations de publication
Date de publication:
12 2020
12 2020
Historique:
received:
04
06
2020
revised:
09
06
2020
accepted:
12
06
2020
pubmed:
6
7
2020
medline:
19
12
2020
entrez:
6
7
2020
Statut:
ppublish
Résumé
Systemic capillary leak syndrome is a rare disorder characterized by dysfunctional inflammatory response, endothelial dysfunction, and extravasation of fluid from the vascular space to the interstitial space leading to shock, hemoconcentration, hypoalbuminemia, and subsequent organ failure. The condition may be idiopathic or secondary to an underlying cause, which can include viral infections. Here we describe a patient with acute coronavirus disease 2019 (COVID-19) infection who presented with hemoconcentration, shock, and hypoalbuminemia. The patient subsequently developed rhabdomyolysis and compartment syndrome of all four extremities, requiring fasciotomies. This is the first reported case of systemic capillary leak syndrome associated with COVID-19 infection. This case adds to the evolving spectrum of inflammatory effects associated with this viral infection.
Identifiants
pubmed: 32622823
pii: S0012-3692(20)31845-6
doi: 10.1016/j.chest.2020.06.049
pmc: PMC7332444
pii:
doi:
Substances chimiques
Crystalloid Solutions
0
Vasoconstrictor Agents
0
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
e267-e268Commentaires et corrections
Type : CommentIn
Type : CommentIn
Informations de copyright
Copyright © 2020 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.
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