Augmented curation of clinical notes from a massive EHR system reveals symptoms of impending COVID-19 diagnosis.
Adult
Betacoronavirus
/ isolation & purification
COVID-19
COVID-19 Testing
Chills
/ epidemiology
Clinical Laboratory Techniques
/ methods
Coronavirus Infections
/ diagnosis
Diarrhea
/ virology
Dysgeusia
/ virology
Female
Fever
/ virology
Humans
Male
Middle Aged
Myalgia
/ virology
Olfaction Disorders
/ virology
Pandemics
Pneumonia, Viral
/ diagnosis
Polymerase Chain Reaction
SARS-CoV-2
COVID-19
SARS-CoV-2
artificial intelligence
electronic health record
human
human biology
infectious disease
machine learning
medicine
microbiology
neural networks
Journal
eLife
ISSN: 2050-084X
Titre abrégé: Elife
Pays: England
ID NLM: 101579614
Informations de publication
Date de publication:
07 07 2020
07 07 2020
Historique:
received:
24
04
2020
accepted:
06
07
2020
pubmed:
8
7
2020
medline:
22
8
2020
entrez:
8
7
2020
Statut:
epublish
Résumé
Understanding temporal dynamics of COVID-19 symptoms could provide fine-grained resolution to guide clinical decision-making. Here, we use deep neural networks over an institution-wide platform for the augmented curation of clinical notes from 77,167 patients subjected to COVID-19 PCR testing. By contrasting Electronic Health Record (EHR)-derived symptoms of COVID-19-positive (COVID
Identifiants
pubmed: 32633720
doi: 10.7554/eLife.58227
pii: 58227
pmc: PMC7410498
doi:
pii:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : National Institute of Allergy and Infectious Diseases
ID : AI110173
Pays : International
Organisme : National Institute of Allergy and Infectious Diseases
ID : AI120698
Pays : International
Organisme : NIAID NIH HHS
ID : R01 AI110173
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI120698
Pays : United States
Organisme : National Institute of Allergy and Infectious Diseases
ID : AI 110173
Pays : International
Informations de copyright
© 2020, Wagner et al.
Déclaration de conflit d'intérêts
TW, KM, SA, AV, SB, AP, MK, PA, ML, ZD, ES, HS, AA, RB, VS is an employee of nference and has financial interests in the company. FS, BP, JO, PB, RR, PV, ZT, SR, MM, WW, DC, GG, AW, WM, JH, AB has a Financial Conflict of Interest in technology used in the research and with Mayo Clinic may stand to gain financially from the successful outcome of the research. This research has been reviewed by the Mayo Clinic Conflict of Interest Review Board and is being conducted in compliance with Mayo Clinic Conflict of Interest policies.
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