Simultaneous Pre-Concentration and HPLC-MS/MS Quantification of Phycotoxins and Cyanotoxins in Inland and Coastal Waters.
Strata™-X
cyanobacterial and algal toxins
environmental waters
multi-class method
single-cartridge SPE
Journal
International journal of environmental research and public health
ISSN: 1660-4601
Titre abrégé: Int J Environ Res Public Health
Pays: Switzerland
ID NLM: 101238455
Informations de publication
Date de publication:
03 07 2020
03 07 2020
Historique:
received:
04
06
2020
revised:
26
06
2020
accepted:
30
06
2020
entrez:
9
7
2020
pubmed:
9
7
2020
medline:
21
11
2020
Statut:
epublish
Résumé
The purpose of this study was to set up a sensitive method for the simultaneous determination of phycotoxins and cyanotoxins-Emerging pollutants with different structures and harmful properties (hepatotoxicity, neurotoxicity and cytotoxicity)-In environmental waters. Due to the low concentrations detected in these samples, a pre-concentration step is required and here it was performed in a single step with a commercial cartridge (Strata™-X), achieving enrichment factors up to 200 and satisfactory recovery (R = 70-118%) in different aqueous matrices. After solid-phase extraction (SPE), toxins were separated and quantified by High Performance Liquid Chromatography- Heated ElectroSpray Ionisation Tandem Mass Spectrometry (HPLC-HESI-MS/MS) in Multiple Reaction Monitoring (MRM) mode. An analytical evaluation of the proposed method was done based on the analytical figures of merit, such as precision and trueness, linearity, selectivity, and sensitivity, and it turned out to be a robust tool for the quantification of ng L
Identifiants
pubmed: 32635172
pii: ijerph17134782
doi: 10.3390/ijerph17134782
pmc: PMC7369962
pii:
doi:
Substances chimiques
Toxins, Biological
0
Water Pollutants, Chemical
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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