"Plug and Play" logic gate construction based on chemically triggered fluorescence switching of gold nanoparticles conjugated with Cy3-tagged aptamer.
Aptamers, Nucleotide
/ chemistry
Base Sequence
Carbocyanines
/ chemistry
Chloramphenicol
/ chemistry
DNA
/ chemistry
Edetic Acid
/ chemistry
Fluorescence
Fluorescence Resonance Energy Transfer
Fluorescent Dyes
/ chemistry
Gold
/ chemistry
Immobilized Nucleic Acids
/ chemistry
Limit of Detection
Logic
Mercury
/ chemistry
Metal Nanoparticles
/ chemistry
Nickel
/ chemistry
Aptamer
Chloramphenicol
Fluorescence resonance energy transfer
Gold nanoparticles
Molecular logic gate
Journal
Mikrochimica acta
ISSN: 1436-5073
Titre abrégé: Mikrochim Acta
Pays: Austria
ID NLM: 7808782
Informations de publication
Date de publication:
09 07 2020
09 07 2020
Historique:
received:
22
03
2020
accepted:
30
06
2020
entrez:
11
7
2020
pubmed:
11
7
2020
medline:
16
6
2021
Statut:
epublish
Résumé
Gold nanoparticles (AuNPs) conjugated with Cy3-tagged aptamer which can specifically recognize chloramphenicol (CAP) (referred to as AuNPs-AptCAP) are described. CAP can trigger the configuration change of CAP binding aptamer, and thus switching the fluorescence of AuNPs-AptCAP through changing the efficiency of the fluorescence resonance energy transfer (FRET) system with Cy3 as donors and AuNPs as recipients. AuNPs-AptCAP exhibits a linear range of CAP concentrations from 26.0 to 277 μg L
Identifiants
pubmed: 32647943
doi: 10.1007/s00604-020-04421-5
pii: 10.1007/s00604-020-04421-5
doi:
Substances chimiques
Aptamers, Nucleotide
0
Carbocyanines
0
Fluorescent Dyes
0
Immobilized Nucleic Acids
0
cyanine dye 3
0
Chloramphenicol
66974FR9Q1
Gold
7440-57-5
Nickel
7OV03QG267
DNA
9007-49-2
Edetic Acid
9G34HU7RV0
Mercury
FXS1BY2PGL
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
437Subventions
Organisme : Natural Science Foundation of Guangdong Province
ID : S2017A030313076
Pays : International
Organisme : Guangzhou Municipal Science and Technology Project
ID : 201803020026
Pays : International
Organisme : Shenzhen Technical Project
ID : JCYJ20170307140752183
Pays : International