The Ingenuity of Bacterial Genomes.


Journal

Annual review of microbiology
ISSN: 1545-3251
Titre abrégé: Annu Rev Microbiol
Pays: United States
ID NLM: 0372370

Informations de publication

Date de publication:
08 09 2020
Historique:
pubmed: 22 7 2020
medline: 23 7 2021
entrez: 22 7 2020
Statut: ppublish

Résumé

The genomes of bacteria contain fewer genes and substantially less noncoding DNA than those of eukaryotes, and as a result, they have much less raw material to invent new traits. Yet, bacteria are vastly more taxonomically diverse, numerically abundant, and globally successful in colonizing new habitats compared to eukaryotes. Although bacterial genomes are generally considered to be optimized for efficient growth and rapid adaptation, nonadaptive processes have played a major role in shaping the size, contents, and compact organization of bacterial genomes and have allowed the establishment of deleterious traits that serve as the raw materials for genetic innovation.

Identifiants

pubmed: 32692614
doi: 10.1146/annurev-micro-020518-115822
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

815-834

Subventions

Organisme : NIGMS NIH HHS
ID : R35 GM118038
Pays : United States

Auteurs

Paul C Kirchberger (PC)

Department of Integrative Biology, University of Texas at Austin, Texas 78712, USA; email: pkirchberger@utexas.edu; marschmi@utexas.edu; howard.ochman@austin.utexas.edu.

Marian L Schmidt (ML)

Department of Integrative Biology, University of Texas at Austin, Texas 78712, USA; email: pkirchberger@utexas.edu; marschmi@utexas.edu; howard.ochman@austin.utexas.edu.

Howard Ochman (H)

Department of Integrative Biology, University of Texas at Austin, Texas 78712, USA; email: pkirchberger@utexas.edu; marschmi@utexas.edu; howard.ochman@austin.utexas.edu.

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Classifications MeSH