The Ingenuity of Bacterial Genomes.
bacterial evolution
chromosome organization
gene origins
genome dynamics
random genetic drift
Journal
Annual review of microbiology
ISSN: 1545-3251
Titre abrégé: Annu Rev Microbiol
Pays: United States
ID NLM: 0372370
Informations de publication
Date de publication:
08 09 2020
08 09 2020
Historique:
pubmed:
22
7
2020
medline:
23
7
2021
entrez:
22
7
2020
Statut:
ppublish
Résumé
The genomes of bacteria contain fewer genes and substantially less noncoding DNA than those of eukaryotes, and as a result, they have much less raw material to invent new traits. Yet, bacteria are vastly more taxonomically diverse, numerically abundant, and globally successful in colonizing new habitats compared to eukaryotes. Although bacterial genomes are generally considered to be optimized for efficient growth and rapid adaptation, nonadaptive processes have played a major role in shaping the size, contents, and compact organization of bacterial genomes and have allowed the establishment of deleterious traits that serve as the raw materials for genetic innovation.
Identifiants
pubmed: 32692614
doi: 10.1146/annurev-micro-020518-115822
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
815-834Subventions
Organisme : NIGMS NIH HHS
ID : R35 GM118038
Pays : United States