Cationic hydrogels prepared from regioselectively azidated (1→3)-α-d-glucan via crosslinking and amination: Physical and adsorption properties.

Adsorption Alkynes / chemistry Amination Azides / chemistry Borohydrides / chemistry Cations / chemistry Copper / chemistry Cross-Linking Reagents / chemistry Cycloaddition Reaction Glucans / chemical synthesis Glucosyltransferases / chemistry Hydrogels / chemistry Hydrogen-Ion Concentration Magnetic Resonance Spectroscopy Organisms, Genetically Modified Serum Albumin, Bovine / chemistry Spectroscopy, Fourier Transform Infrared Streptococcus salivarius / enzymology Sucrose / chemistry

(1→3)-α-d-glucan Azidation Cationic hydrogel CuAAC Glucosyltransferase Streptococcus salivarius

Journal

Carbohydrate polymers

ISSN: 1879-1344

Titre abrégé: Carbohydr Polym

Pays: England

ID NLM: 8307156

Informations de publication

Date de publication:
01 Oct 2020

Historique:

received: 10 04 2020

revised: 18 05 2020

accepted: 31 05 2020

entrez: 29 7 2020

pubmed: 29 7 2020

medline: 15 4 2021

Statut: ppublish

Résumé

Cationic hydrogels with amino groups were successfully prepared using (1→3)-α-d-glucan synthesized by glucosyltransferase J (GtfJ) cloned from Streptococcus salivarius through a three-step reaction: (i) Azido groups were regioselectively introduced at the C6 position of (1→3)-α-d-glucan by a bromination-azidation process (degree of substitution 0.94), (ii) Azido groups were partially crosslinked with 1,8-nonadiyne via a copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reaction, (iii) Azido groups that were unused for crosslinking were reduced to amino groups by sodium borohydride (NaBH

Identifiants

DOI: 10.1016/j.carbpol.2020.116543 PMID: 32718638

pubmed: 32718638

pii: S0144-8617(20)30717-7

doi: 10.1016/j.carbpol.2020.116543

pii:

doi:

Substances chimiques

Alkynes 0

Azides 0

Borohydrides 0

Cations 0

Cross-Linking Reagents 0

Glucans 0

Hydrogels 0

Serum Albumin, Bovine 27432CM55Q

Sucrose 57-50-1

Copper 789U1901C5

sodium borohydride 87L0B9CPPA

Glucosyltransferases EC 2.4.1.-

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

Pagination

116543

Cationic hydrogels prepared from regioselectively azidated (1→3)-α-d-glucan via crosslinking and amination: Physical and adsorption properties.

Journal

Informations de publication

Résumé

Identifiants

Substances chimiques

Types de publication

Langues

Sous-ensembles de citation

Pagination

Informations de copyright

Auteurs

Qinfeng He (Q)

Ryosuke Kusumi (R)

Satoshi Kimura (S)

Ung-Jin Kim (UJ)

Masahisa Wada (M)

Articles similaires

Initial pH determines the morphological characteristics and secondary metabolite production in Aspergillus terreus and Streptomyces rimosus cocultures.

Drug repurposing against fucosyltransferase-2 via docking, STD-NMR, and molecular dynamic simulation studies.

Stem cell-homing biomimetic hydrogel promotes the repair of osteoporotic bone defects through osteogenic and angiogenic coupling.

Microemulsion-based topical hydrogels containing lemongrass leaf essential oil (Cymbopogon citratus (DC.) Stapf) and mango seed kernel extract (Mangifera indica Linn) for acne treatment: Preparation and in-vitro evaluations.

Classifications MeSH