Mediastinal tumor resection in a patient with spinocerebellar degeneration.


Journal

Journal of cardiothoracic surgery
ISSN: 1749-8090
Titre abrégé: J Cardiothorac Surg
Pays: England
ID NLM: 101265113

Informations de publication

Date de publication:
29 Jul 2020
Historique:
received: 03 03 2020
accepted: 08 07 2020
entrez: 31 7 2020
pubmed: 31 7 2020
medline: 6 1 2021
Statut: epublish

Résumé

In spinocerebellar degeneration (SCD) patients, general and regional anesthesia may cause postoperative dysfunction of respiratory, nerve and muscle systems. We present the surgical case of thymoma developed in patient with SCD. A 47-year-old woman with spinocerebellar degeneration was admitted because of a well-defined mass measuring 48 × 31 mm in anterior mediastinum. She showed limb, truncal, ocular, and speech ataxia; hypotonia; areflexia; sensory disturbances; and muscle weakness. Her eastern cooperative oncology group performance status was 4. Surgical resection was performed via video-assisted thoracic surgery and under general anesthesia only without epidural analgesia. The mass was diagnosed as type B1 thymoma without capsular invasion (Masaoka stage I). The patients got a good postoperative course by cooperation with anesthesiologists and neurologists in perioperative managements. She has been well over 3 years of follow-up. In conclusion, careful surgical and anesthesia management is essential for providing an uneventful postoperative course in patients with SCD. Especially, selection of minimal invasive approach and avoid diaphragmatic nerve damage are the most important points in surgical procedures.

Sections du résumé

BACKGROUND BACKGROUND
In spinocerebellar degeneration (SCD) patients, general and regional anesthesia may cause postoperative dysfunction of respiratory, nerve and muscle systems. We present the surgical case of thymoma developed in patient with SCD.
CASE PRESENTATION METHODS
A 47-year-old woman with spinocerebellar degeneration was admitted because of a well-defined mass measuring 48 × 31 mm in anterior mediastinum. She showed limb, truncal, ocular, and speech ataxia; hypotonia; areflexia; sensory disturbances; and muscle weakness. Her eastern cooperative oncology group performance status was 4. Surgical resection was performed via video-assisted thoracic surgery and under general anesthesia only without epidural analgesia. The mass was diagnosed as type B1 thymoma without capsular invasion (Masaoka stage I). The patients got a good postoperative course by cooperation with anesthesiologists and neurologists in perioperative managements. She has been well over 3 years of follow-up.
CONCLUSIONS CONCLUSIONS
In conclusion, careful surgical and anesthesia management is essential for providing an uneventful postoperative course in patients with SCD. Especially, selection of minimal invasive approach and avoid diaphragmatic nerve damage are the most important points in surgical procedures.

Identifiants

pubmed: 32727532
doi: 10.1186/s13019-020-01218-8
pii: 10.1186/s13019-020-01218-8
pmc: PMC7389681
doi:

Substances chimiques

Analgesics, Opioid 0
Anesthetics, Intravenous 0
Neuromuscular Nondepolarizing Agents 0
Remifentanil P10582JYYK
Rocuronium WRE554RFEZ
Propofol YI7VU623SF

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

197

Références

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J Neurol. 2000 Oct;247(10):812-3
pubmed: 11127543
J Anaesthesiol Clin Pharmacol. 2011 Apr;27(2):249-52
pubmed: 21772692
Anesth Analg. 1997 Nov;85(5):1071-3
pubmed: 9356102
Can J Anaesth. 2007 Jun;54(6):467-70
pubmed: 17541076
Brain. 1997 Dec;120 ( Pt 12):2141-8
pubmed: 9448569
Anaesthesia. 1982 Jun;37(6):695-6
pubmed: 6211998
Ann Thorac Cardiovasc Surg. 2000 Apr;6(2):125-6
pubmed: 10870008

Auteurs

Eiyu Tsuboi (E)

Division of Chest Surgery, Department of Surgery, Toho University School of Medicine, 6-11-1 Omori-nishi, Ota-ku, Tokyo, 143-8541, Japan.

Yoko Azuma (Y)

Division of Chest Surgery, Department of Surgery, Toho University School of Medicine, 6-11-1 Omori-nishi, Ota-ku, Tokyo, 143-8541, Japan.

Takashi Makino (T)

Division of Chest Surgery, Department of Surgery, Toho University School of Medicine, 6-11-1 Omori-nishi, Ota-ku, Tokyo, 143-8541, Japan.

Takashi Terada (T)

Department of Anesthesiology, Toho University School of Medicine, Tokyo, Japan.

Hajime Otsuka (H)

Division of Chest Surgery, Department of Surgery, Toho University School of Medicine, 6-11-1 Omori-nishi, Ota-ku, Tokyo, 143-8541, Japan.

Atsushi Sano (A)

Division of Chest Surgery, Department of Surgery, Toho University School of Medicine, 6-11-1 Omori-nishi, Ota-ku, Tokyo, 143-8541, Japan.

Satoshi Koezuka (S)

Division of Chest Surgery, Department of Surgery, Toho University School of Medicine, 6-11-1 Omori-nishi, Ota-ku, Tokyo, 143-8541, Japan.

Takashi Sakai (T)

Division of Chest Surgery, Department of Surgery, Toho University School of Medicine, 6-11-1 Omori-nishi, Ota-ku, Tokyo, 143-8541, Japan.

Naobumi Tochigi (N)

Department of Surgical Pathology, Toho University School of Medicine, Tokyo, Japan.

Akira Iyoda (A)

Division of Chest Surgery, Department of Surgery, Toho University School of Medicine, 6-11-1 Omori-nishi, Ota-ku, Tokyo, 143-8541, Japan. aiyoda@med.toho-u.ac.jp.

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Classifications MeSH