COVID-19 in Hospitalized Patients on Chronic Peritoneal Dialysis: A Case Series.
Adult
Aged
Betacoronavirus
/ genetics
COVID-19
Coronavirus Infections
/ complications
Electronic Health Records
/ statistics & numerical data
Female
Hospital Mortality
Hospitalization
/ statistics & numerical data
Humans
Kidney Failure, Chronic
/ complications
Male
Middle Aged
New York
/ epidemiology
Pandemics
Peritoneal Dialysis
/ adverse effects
Peritonitis
/ diagnosis
Pneumonia, Viral
/ complications
RNA, Viral
/ isolation & purification
SARS-CoV-2
Coronavirus disease 2019
End-stage kidney disease
Nephrology
Peritoneal dialysis
Journal
American journal of nephrology
ISSN: 1421-9670
Titre abrégé: Am J Nephrol
Pays: Switzerland
ID NLM: 8109361
Informations de publication
Date de publication:
2020
2020
Historique:
received:
24
06
2020
accepted:
10
07
2020
pubmed:
31
7
2020
medline:
2
9
2020
entrez:
31
7
2020
Statut:
ppublish
Résumé
The COVID-19 pandemic has affected the end-stage kidney disease (ESKD) population, with high mortality rates reported among patients on hemodialysis. However, the degree to which it has affected the peritoneal dialysis (PD) population in the United States has not yet been elucidated. In this report, we describe the clinical characteristics, presentations, clinical course, and outcomes of ESKD patients on PD hospitalized with COVID-19. We describe the characteristics, presentation, and outcomes of adult ESKD patients on chronic PD hospitalized with CO-VID-19 in our 13 major hospitals in the NY health system using descriptive statistical analysis. Of 419 hospitalized patients with ESKD, 11 were on chronic PD therapy (2.6%). Among those 11, 3 patients required mechanical ventilation, 2 of whom died. Of the entire cohort, 9 of the 11 patients (82%) were discharged alive. While fever was a common presentation, more than half of our patients also presented with diarrhea. Interestingly, 3 patients were diagnosed with culture-negative peritonitis during their hospitalization. Seven patients reported positive SARS-CoV-2 exposure from a member of their household. Hospitalized patients on PD with COVID-19 had a relatively mild course, and majority of them were discharged home.
Sections du résumé
BACKGROUND
The COVID-19 pandemic has affected the end-stage kidney disease (ESKD) population, with high mortality rates reported among patients on hemodialysis. However, the degree to which it has affected the peritoneal dialysis (PD) population in the United States has not yet been elucidated. In this report, we describe the clinical characteristics, presentations, clinical course, and outcomes of ESKD patients on PD hospitalized with COVID-19.
METHODS
We describe the characteristics, presentation, and outcomes of adult ESKD patients on chronic PD hospitalized with CO-VID-19 in our 13 major hospitals in the NY health system using descriptive statistical analysis.
RESULTS
Of 419 hospitalized patients with ESKD, 11 were on chronic PD therapy (2.6%). Among those 11, 3 patients required mechanical ventilation, 2 of whom died. Of the entire cohort, 9 of the 11 patients (82%) were discharged alive. While fever was a common presentation, more than half of our patients also presented with diarrhea. Interestingly, 3 patients were diagnosed with culture-negative peritonitis during their hospitalization. Seven patients reported positive SARS-CoV-2 exposure from a member of their household.
CONCLUSION
Hospitalized patients on PD with COVID-19 had a relatively mild course, and majority of them were discharged home.
Identifiants
pubmed: 32731215
pii: 000510259
doi: 10.1159/000510259
pmc: PMC7490491
doi:
Substances chimiques
RNA, Viral
0
Types de publication
Journal Article
Multicenter Study
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
669-674Subventions
Organisme : NIDDK NIH HHS
ID : R01 DK118017
Pays : United States
Investigateurs
Mersema Abate
(M)
Richard L Barnett
(RL)
Hugo Paz Andrade
(HP)
Alessandro Bellucci
(A)
Antonio G Corona
(AG)
Bessy Suyin Flores Chang
(BSF)
Mark Finger
(M)
Michael Gitman
(M)
Pravin C Singhal
(PC)
Hitesh H Shah
(HH)
Candice Halinski
(C)
Rimda Wanchoo
(R)
Azzour D Hazzan
(AD)
Shamir Hasan
(S)
Rushang Parikh
(R)
Purva Sharma
(P)
Susana Hong
(S)
Yuriy Khanin
(Y)
Airen Kuan
(A)
Varun Madireddy
(V)
Gayatri Nair
(G)
Vinay V Nair
(VV)
Abdulrahman Muzib
(A)
Daniel W Ross
(DW)
Vipulbhai Sakhiya
(V)
Richard Schwarz
(R)
Madhu C Bhaskaran
(MC)
Informations de copyright
© 2020 S. Karger AG, Basel.
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